Selenium Sulphide Pharmacology

Selenium Sulphide

About Selenium Sulphide
Selenium compound, Antifungal,anti-dandruff,in seborrheic dermatitis.
Mechanism of Action of Selenium Sulphide
Topical Selenium sulfide produces antimitotic (cytostatic) action on cells of the epidermis and follicular epithelium and causes a reduction in the turnover of epidermal cells and reduces corneocyte production.
It also has local irritant, antibacterial and mild antifungal activity. Selenium sulfide is an antifungal agent often used in shampoos for the treatment of dandruff and Seborrheic dermatitis. Selenium sulfide inhibits the growth of P. ovale. It slows the growth of both hyperproliferative and normal cells in dandruff and Seborrheic dermatitis. Selenium sulfide decreases the rate of incorporation of radioactively labeled Thymidine into the DNA of dermal epithelial cells.
Selenium sulphide specifically destroys dermatophyte. It also causes a decrease in the production of cells in the top layer of skin, as well as the amount of natural oil sebum produced by the sebaceous glands in the skin. Selenium sulphide therefore kills the fungi responsible for causing this inflammation, as well as controls the itching and scaling associated with dandruff and Seborrheic dermatitis of the scalp.
Pharmacokinets of Selenium Sulphide
Absorption: Absorption through intact skin is negligible.
Onset of Action for Selenium Sulphide
N/A
Duration of Action for Selenium Sulphide
N/A
Half Life of Selenium Sulphide
N/A
Side Effects of Selenium Sulphide
1. Alopecia (Hair loss)
2. Irritation
3. Sensitisation
4. Hair discoloration
5. Oiliness or dryness of scalp and hair
Contra-indications of Selenium Sulphide
1. Hypersensitivity to Selenium sulphide
2. Broken skin or open wounds
3. Inflamed skin
Special Precautions while taking Selenium Sulphide
1. Avoid contact with eyes.
2. Gold, silver and other metallic jewellery should be removed prior to use.
3. This preparation should be thoroughly rinsed from the hair before dyeing, tinting or waving the hair. It should not be applied for a period of two days before or after any of these procedures
4. For external use only.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Selenium Sulphide
Scalp disorders
1. Dandruff
2. Seborrhoeic dermatitis
3. Tinea versicolor
Interactions for Selenium Sulphide
N/A
Typical Dosage for Selenium Sulphide
Topical: Selenium sulphide 2.5% lotion or shampoo is used.
Tinea versicolor: Apply once daily for 1 week.
Seborrheic dermatitis and dandruff: Apply twice weekly for 2 weeks then gradually decrease the dose like once weekly, every 2 weeks
Schedule of Selenium Sulphide
N/A
Storage Requirements for Selenium Sulphide
Store at cool place in a tightly closed container. Keep out of the reach of children.
Effects of Missed Dosage of Selenium Sulphide
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Selenium Sulphide
Give supportive measures and symptomatic treatment.

Home Delivery for Selenium Sulphide in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including selenium sulphide.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for selenium sulphide and other medicines and health products. Home delivery services for selenium sulphide may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take selenium sulphide only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for selenium sulphide before they complete the sale. You can get this information while placing the order for selenium sulphide with the pharmacy.

Selenium Sulphide is a generic medicine name and there are several brands available for it. Some of the brands for selenium sulphide might be better known than selenium sulphide itself. If the pharmacy that's willing to deliver medicines to your home doesn't have selenium sulphide in stock, you can ask for one of the branded alternatives for selenium sulphide.