Beclomethasone (Nasal) Pharmacology

Beclomethasone (Nasal)

About Beclomethasone (Nasal)
Potent glucocorticoid, Treat nasal symptoms and nasal polyps.
Mechanism of Action of Beclomethasone (Nasal)
Beclomathasone (nasal) exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows its migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gamma interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells.
5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Beclomethasone (Nasal)
N/A
Onset of Action for Beclomethasone (Nasal)
N/A
Duration of Action for Beclomethasone (Nasal)
N/A
Half Life of Beclomethasone (Nasal)
N/A
Side Effects of Beclomethasone (Nasal)
1.Lightheadedness
2.Headache
3.Sneezing
4.Nasal irritation
5.Stinging
6.Drying of nasal tissue
Contra-indications of Beclomethasone (Nasal)
Hypersensitivity to Beclomethasone
Special Precautions while taking Beclomethasone (Nasal)
1.Glaucoma
2.Herpes-type infection of the eye infection
3.Recent nasal surgery
4.Nasal sores
5.Liver disease
6.Tuberculosis
7.Underactive thyroid
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Beclomethasone (Nasal)
1.To reduce swelling and inflammation of nasal tissue
2.Nasal congestion
Interactions for Beclomethasone (Nasal)
N/A
Typical Dosage for Beclomethasone (Nasal)
Apply the nasal preparation as directed by the Physician.
Schedule of Beclomethasone (Nasal)
N/A
Storage Requirements for Beclomethasone (Nasal)
Store this medication at room temperature away from moisture and heat.
Effects of Missed Dosage of Beclomethasone (Nasal)
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Beclomethasone (Nasal)
Give supportive measures and symptomatic treatment.

Home Delivery for Beclomethasone (Nasal) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including beclomethasone (nasal).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for beclomethasone (nasal) and other medicines and health products. Home delivery services for beclomethasone (nasal) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take beclomethasone (nasal) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for beclomethasone (nasal) before they complete the sale. You can get this information while placing the order for beclomethasone (nasal) with the pharmacy.

Beclomethasone (Nasal) is a generic medicine name and there are several brands available for it. Some of the brands for beclomethasone (nasal) might be better known than beclomethasone (nasal) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have beclomethasone (nasal) in stock, you can ask for one of the branded alternatives for beclomethasone (nasal).