Betamethasone (Nasal) Pharmacology

Betamethasone (Nasal)

About Betamethasone (Nasal)
Glucocorticoid steroid, seasonal or perennial allergic and nonallergic (vasomotor) .
Mechanism of Action of Betamethasone (Nasal)
Betamethasone exerts it`s pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits phospholipase A2 and thus decreases the production of Prostaglandins, leukotriens (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-alpha, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemotaxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.Betamethasone can be given as a nasal spray to treat and prevent the inflammation that can occur in conditions such as allergies.
Pharmacokinets of Betamethasone (Nasal)
Onset of Action for Betamethasone (Nasal)
Duration of Action for Betamethasone (Nasal)
Half Life of Betamethasone (Nasal)
Side Effects of Betamethasone (Nasal)

3.Smell and taste disturbances
4.Irritation of the tissues in the nose
5.Dryness of the nose and throat
6.Local sensitivity reactions
Contra-indications of Betamethasone (Nasal)
1.Perforated ear drum
2.After nasal surgery
Special Precautions while taking Betamethasone (Nasal)
2.Herpes-type infection of the eye infection
3.Recent nasal surgery
4.Nasal sores
5.Liver disease
7.Underactive thyroid
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Children Related Information
Use with caution
Indications for Betamethasone (Nasal)
1.Otitis externa
2.Non-allergic rhinitis
Interactions for Betamethasone (Nasal)
Typical Dosage for Betamethasone (Nasal)
Appy the medicament as directed by the Physician
Schedule of Betamethasone (Nasal)
Storage Requirements for Betamethasone (Nasal)
Store this medication at room temperature away from moisture and heat.Keep out of the reach of children.
Effects of Missed Dosage of Betamethasone (Nasal)
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Betamethasone (Nasal)
Give supportive measures and symptomatic treatment.

Home Delivery for Betamethasone (Nasal) in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including betamethasone (nasal).

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for betamethasone (nasal) and other medicines and health products. Home delivery services for betamethasone (nasal) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take betamethasone (nasal) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for betamethasone (nasal) before they complete the sale. You can get this information while placing the order for betamethasone (nasal) with the pharmacy.

Betamethasone (Nasal) is a generic medicine name and there are several brands available for it. Some of the brands for betamethasone (nasal) might be better known than betamethasone (nasal) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have betamethasone (nasal) in stock, you can ask for one of the branded alternatives for betamethasone (nasal).