Distribution- Widely distributed in the body.80-90% bound to the plasma proteins. It crosses the blood brain barrier.
Metabolism- It metabolized in the liver to its metabolites. Deacetylvinorelbine is its active metabolite and vinorelbine N-oxide is its inactive metabolite.
Excretion- Excreted via urine (18%, 11% as unchanged form) and bile.
3. Lowered resistance to infection
4. Bruising or unusual bleeding
7. Sore in mouth
8. Taste changes
10. Loss of appetite
11. Visual changes
12. Black, tarry stools
13. Blood in urine or in stool
14. Cough or hoarseness
17. Lower back or side pain
18. Painful or difficult urination
19. Pinpoint red spot on skin
20. Slurred speech
21. Swelling on leg or lower leg
22. Shortness of breath
23. Pulmonary fibrosis
32. Bone marrow suppression
34. Musle weakness
2. Pretreatment granulocyte count <1000 cells/mm3
Cautiously use in patients with :
1. Bone marrow suppression
2. Recent radiation therapy
3. Recent chemotherapy
4. Hepatic insufficiency
2. Breast cancer
3. Cervical cancer
4. Ovarian cancer (epithelial)
5. Testicular cancer
6. Hodkins disease
8. Squamous cell carcinoma
9. Cancer of head and neck
10. Renal cell cancer
11. Kaposis sarcoma
Mitomycin: Produce pulmonary reactions
30mg/metre square weekly over a period of 6- 10 minutes.
Home Delivery for Vinorelbine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including vinorelbine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for vinorelbine and other medicines and health products. Home delivery services for vinorelbine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take vinorelbine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for vinorelbine before they complete the sale. You can get this information while placing the order for vinorelbine with the pharmacy.
Vinorelbine is a generic medicine name and there are several brands available for it. Some of the brands for vinorelbine might be better known than vinorelbine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have vinorelbine in stock, you can ask for one of the branded alternatives for vinorelbine.