Flutamide Pharmacology


About Flutamide
Non steroidal antiandrogen, Antineoplastic Agent,in Female hirsutism.
Mechanism of Action of Flutamide
Drug has a structural similarity to the male hormone testosterone. Thus it binds to the receptors of testosterone present on the prostate cancer cells. This prevents the attachment and action of testosterone on the cancer cells. Due to the absence of testosterone, cancer cells cannot grow and death of it occurs
Pharmacokinets of Flutamide
Absorption- Well absorbed after oral administration
Distribution- Drug concentrates to the prostate gland and cancer cells produced by it.
94-96% bound to the plasma proteins
Excretion- Excreted via urine
Onset of Action for Flutamide
Duration of Action for Flutamide
Plasma half-life 6 hours
Half Life of Flutamide
Side Effects of Flutamide
1. Hot flashes
2. Breast tenderness
3. Decrease in sexual desire
4. Decrease in appetite
5. Sensitivity to sunlight
6. Diarrhea
7. Depression
8. Nervousness
9. Skin rash
10. Swelling of the feet or hands
11. Shortness of breath
12. Weakness
13. Fast heartbeat
14. Leucopenia
15. Thrompocytopenia
16. Hepatitis
17. Gynecomastia
Contra-indications of Flutamide
1. Hyper sensitivity to the drug
2. Hepatic impairment
3. Chronic depression
4. History of thromboembolism
Special Precautions while taking Flutamide
Monitor patient`s liver functions regularly
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Flutamide
Prostate cancer (metastatic)
Interactions for Flutamide
Typical Dosage for Flutamide
250mg, 3 times daily
Schedule of Flutamide
Storage Requirements for Flutamide
Stored at room temperature. Protect from light and excessive heat. Keep out of reach of children
Effects of Missed Dosage of Flutamide
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Flutamide
Give symptomatic and supportive treatment

Home Delivery for Flutamide in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including flutamide.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for flutamide and other medicines and health products. Home delivery services for flutamide may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take flutamide only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for flutamide before they complete the sale. You can get this information while placing the order for flutamide with the pharmacy.

Flutamide is a generic medicine name and there are several brands available for it. Some of the brands for flutamide might be better known than flutamide itself. If the pharmacy that's willing to deliver medicines to your home doesn't have flutamide in stock, you can ask for one of the branded alternatives for flutamide.