Glucose Pharmacology

Glucose

About Glucose
Monosaccharide,Aldohexose, Nutritive,sweetner.
Mechanism of Action of Glucose
Glucose is a simple carbohydrate and is used as energy source in man. It is readily converted to fat which provides a rich store of energy in concentrated form. Glucose is also stored in the liver and muscles as glycogen. When a rapid raise in blood sugar is demanded by the body, glycogen is quickly converted to D-glucose. When the supply of glucose is insufficient, the body mobilises fat stores which are converted to acetate with production of energy by the same oxidative pathways employed in the combustion of glucose.
Glucose is also the source of glucuronic acid, with which many foreign substances and their metabolites come to form excretion products. It probably provides the basic substances required for the formation of hyaluronates and chrondroitin sulphates, the supporting structures of the organism. It can be converted to a pentose essential for the formation of nucleic acid by the cells.
Glucose solutions are used to replace water deficits and should be given when there is no loss of electrolytes. Dehydration usually occurs when the output is not matched with comparable input. Dehydration occurs in coma or dysphagia or in the aged who may not drink water in sufficient amounts.Glucose solutions can be given with bicarbonate, calcium and insulin for the emergency management of hyperkalaemia. They are also given after correction of hyperglycemia, during treatment of diabetic ketoacidosis.They must be accompanied by continuing insulin infusion
Pharmacokinets of Glucose
Absorption: Glucose is absorbed orally or intravenously. Metabolism: It is metabolized to carbon dioxide and water with release of energy.
Onset of Action for Glucose
N/A
Duration of Action for Glucose
N/A
Half Life of Glucose
N/A
Side Effects of Glucose
1.Fever
2.Infection at the site of injection
3.Venous thrombosis
4.Phlebitis
5.Extravasation
Contra-indications of Glucose
1. Diabetic coma
2. Blood sugar levels are excessively high
3. Anuria
4. Intracranial haemorrhage
5. Intraspinal haemorrhage
6. In patients with delirium who are already dehydrated.
7. Avoid use in ischaemic stroke.
8. Hypersensitivity to corn or corn products.
Special Precautions while taking Glucose
1.Diabetes mellitus
2.Severe undernutrition
3.Thiamine deficiency
4.Hypokalaemia
5.Hypophosphataemia
6.Hypomagnesaemia
7.Haemodilution
8.Sepsis and trauma
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Glucose
1.Fluid replacement therapy
2.Severe hypoglycemia resulting from Insulin therapy.
Interactions for Glucose
N/A
Typical Dosage for Glucose
The dose is variable and depends upon the indication, clinical condition, age, size and fluid, electrolyte and acid-base balance of the patient.
Adults
2 - 6 litres depending on severity of condition.
Children: the dose is the same as for adults.
Neonates and infants, the usual dose is 2 mL/kg of 10 - 25% glucose solution,
Schedule of Glucose
N/A
Storage Requirements for Glucose
Store below 25?C. Protect from light.
Effects of Missed Dosage of Glucose
N/A
Effects of Overdose of Glucose
Give supportive measures and symptomatic treatment.

Home Delivery for Glucose in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including glucose.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for glucose and other medicines and health products. Home delivery services for glucose may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take glucose only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for glucose before they complete the sale. You can get this information while placing the order for glucose with the pharmacy.

Glucose is a generic medicine name and there are several brands available for it. Some of the brands for glucose might be better known than glucose itself. If the pharmacy that's willing to deliver medicines to your home doesn't have glucose in stock, you can ask for one of the branded alternatives for glucose.