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- Pharmacology For Vitamin B-Complex + Vitamin C + Zinc + Lactobacillus
Vitamin B-Complex + Vitamin C + Zinc + Lactobacillus Pharmacology
Vitamin B-Complex + Vitamin C + Zinc + LactobacillusAbout Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AMechanism of Action of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/APharmacokinets of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AOnset of Action for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/ADuration of Action for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AHalf Life of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/ASide Effects of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AContra-indications of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/ASpecial Precautions while taking Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AInteractions for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/ATypical Dosage for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/ASchedule of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AStorage Requirements for Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AEffects of Missed Dosage of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/AEffects of Overdose of Vitamin B-Complex + Vitamin C + Zinc + LactobacillusN/A
Vitamin B-ComplexAbout Vitamin B-ComplexVitamin B-complex are group of vitamins, which include Thiamine (B1),Riboflavin (B2),Niacin (B3),Pantothenic acid (B5),Pyridoxine (B6),Cyanocobalamin (B12),Folic acid and Biotin.
These vitamins are essential for the breakdown of carbohydrates into glucose (this provides energy for the body),the breakdown of fats and proteins (which aids the normal functioning of the nervous system),muscle tone in the stomach and intestinal tract,Skin,Hair,Eyes,Mouth and Liver
Mechanism of Action of Vitamin B-ComplexN/APharmacokinets of Vitamin B-ComplexN/AOnset of Action for Vitamin B-ComplexN/ADuration of Action for Vitamin B-ComplexN/AHalf Life of Vitamin B-ComplexN/ASide Effects of Vitamin B-Complex1.Drowsiness
5.Numbness of the skin
Contra-indications of Vitamin B-ComplexHypersensitivity to the ingredient of Vitamin B-complexSpecial Precautions while taking Vitamin B-Complex1.Pernecious anaemia
2.Patient receiving dialysisPregnancy Related InformationMay be used.Old Age Related InformationMay be used.Breast Feeding Related InformationMay be used.Children Related InformationMay be used.Indications for Vitamin B-Complex1.Vitamin deficiency states
2. As an adjuvant to antibiotic therapy
3. Combinations with lactobacillus are indicated in aphthous stomatitis, thrush.Interactions for Vitamin B-ComplexSulfinpyrazone: Uricosuric effect of sulfinpyrazone may be inhibited by niacin.
Levodopa: Pyridoxine reduces efficacy of levodopa. Avoid supplemental vitamins that contain greater then 5 mg pyridoxine in the daily dose.
Phenobarbital: Serum levels of Phenobarbital may be decreased if used concomitantly with pyridoxine.
Phenytoin: Pyridoxine decreases serum levels of phenytoin.
Dapsone: PABA antagonizes anti-malarial effect of dapsone.
Typical Dosage for Vitamin B-ComplexI tablet /daySchedule of Vitamin B-ComplexN/AStorage Requirements for Vitamin B-ComplexStore at room temperature. Keep out of the reach of children.Protect from heat, light and moisture.Effects of Missed Dosage of Vitamin B-ComplexTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin B-ComplexGive supportive measures and symptomatic treatment.
Vitamin CAbout Vitamin CWater soluble vitamin, antioxidant.Mechanism of Action of Vitamin CVitamin C exerts it`s action by influencing the biologic oxidations and reductions used in cellular respirations. It directly stimulates collagen synthesis and maintains intracellular connective tissue. It involves in various metabolic reactions such as 1).Hydroxylation of praline and lysine residues of protocollagen which is essential for formation and stabilization of collagen triple helix, 2).hydroxylation of carnitine, 3).Conversion of folic acid to folinic acid, 4).biosynthesis of adrenal steroids, catecholamines, oxytocin, and ADH, 5).Metabolism of cyclic nucleotides and prostaglandins. Vitamin C is important in resistance to infections.Pharmacokinets of Vitamin CAbsorption: Well absorbed orally.
Distribution: Widely distributed both extracellularly and intracellularly, It crosses the placenta and also distributed in to the breast milk.
Metabolism: Metabolized in the liver; partly oxidized in to active dehydroascorbic acid and inactive metabolites.
Excretion: Inactive metabolites and extra drug is excreted through urine.
Onset of Action for Vitamin CN/ADuration of Action for Vitamin CN/AHalf Life of Vitamin CN/ASide Effects of Vitamin C1. Discomfort at injection site
2. Acid urine
3. Renal calculi
Contra-indications of Vitamin CNo known contraindicationsSpecial Precautions while taking Vitamin C1. Renal impairment
2. Ingestion of large doses during pregnancy has resulted in scurvy in neonates
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationMay be usedIndications for Vitamin C1. Scurvy
2. Prophylaxis and treatment of vitamin C deficiency
3. As an antioxidant to maintain natural colour and flavour of food items
4. For acidification of urine
5. Capillary fragility
6. Dental caries
Interactions for Vitamin COral contraceptives and estrogens: Vitamin C increases serum levels of oestrogen resulting in adverse reactions .
Warfarin: The anticoagulant effects of warfarin is reduced.
Lab Tests: Large doses (>500 mg) of vitamin C may cause false negative urine glucose determinations. May result in false negative amine dependent stool occult blood tests.Typical Dosage for Vitamin COral:
Adults: 50 to 1000mg/day depending up on the requirement.
Pregnancy and lactation: 100 to 150mg/day
Children: 30 to 100mg/day.
Adults: 1000mg twice daily to thrice daily.
Children: 300mg to 1000mg daily.
Sub clinical scurvy:
Oral, S.C., I.M., or I.V.: 100 to 250mg once daily or twice daily depending up on the severity of the condition. Then give a maintenance dosage of 50mg/day.
Children: 100 to 300mg depending up on the severity. Then give a maintenance dose of 35mg/day.
Schedule of Vitamin CC1 (Oral)
C (Parenteral)Storage Requirements for Vitamin CStore in a cool dry area in a well closed container. Protects from moisture, light and direct heat.Effects of Missed Dosage of Vitamin CTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin CDiscontinue the therapy and provide symptomatic and supportive measures.
ZincAbout ZincTrance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.Mechanism of Action of ZincZinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.Pharmacokinets of ZincAbsorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.Onset of Action for ZincN/ADuration of Action for ZincN/AHalf Life of ZincN/ASide Effects of Zinc1. Nausea
3. Abdominal distress
4. Gastric ulceration
Contra-indications of ZincN/ASpecial Precautions while taking Zinc1.Don`t exceed prescribed dose
Pregnancy Related InformationUse with cautionOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Zinc1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
Interactions for ZincFluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.
Typical Dosage for ZincAdults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of ZincN/AStorage Requirements for ZincStore at a temperature below 30 degree CEffects of Missed Dosage of ZincTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ZincProvide symptomatic treatment and supportive measures
LactobacillusAbout LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatment
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