Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2 Pharmacology

Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2

About Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Mechanism of Action of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Pharmacokinets of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Onset of Action for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Duration of Action for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Half Life of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Side Effects of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Contra-indications of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Special Precautions while taking Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Interactions for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Typical Dosage for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Schedule of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Storage Requirements for Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Effects of Missed Dosage of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A
Effects of Overdose of Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2
N/A

Iron (Ferric ammonium citrate)

About Iron (Ferric ammonium citrate)
An iron-containing salt,oral iron preparation, Antianemic,hematinic.
Mechanism of Action of Iron (Ferric ammonium citrate)
Ferric Ammonium Citrate contains between 16.5% and 18.5% of iron. It exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues. Ferric ammonium citrate is given by mouth as a source of iron for iron-deficiency anaemia.Ferric salts have not been preferred over ferrous salts as the ferric ion first requires reduction to ferrous form in the intestinal lumen. The bio-availability of iron from ferric salts is 3 to 4 times less than that of ferrous form.Ferric ammonium citrate (18% elemental iron) is the most commonly used ferric salts.
Pharmacokinets of Iron (Ferric ammonium citrate)
Absorption: Ferric is converted into Ferrous form and it is absorbed in ferrous form. It is poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Ferric ammonium citrate)
N/A
Duration of Action for Iron (Ferric ammonium citrate)
N/A
Half Life of Iron (Ferric ammonium citrate)
N/A
Side Effects of Iron (Ferric ammonium citrate)
1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations.
Contra-indications of Iron (Ferric ammonium citrate)
1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions
Special Precautions while taking Iron (Ferric ammonium citrate)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Ferric ammonium citrate)
1. Iron deficiency
2. Iron deficiency anaemia
Interactions for Iron (Ferric ammonium citrate)
N/A
Typical Dosage for Iron (Ferric ammonium citrate)
Adult: I capsule or 15ml twice daily after meals.
Children: 5 ml twice daily after meals.
Schedule of Iron (Ferric ammonium citrate)
H
Storage Requirements for Iron (Ferric ammonium citrate)
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Iron (Ferric ammonium citrate)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Ferric ammonium citrate)
Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

Iron (Liver extract)

About Iron (Liver extract)
Oral iron preparation, Antianemic,hematinic.
Mechanism of Action of Iron (Liver extract)
Liver extract and desiccated (dried) liver are given as iron supplements. Iron formulations exert haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Liver extract)
Absorption:It is completely absorbed after parenteral administration.
Onset of Action for Iron (Liver extract)
N/A
Duration of Action for Iron (Liver extract)
N/A
Half Life of Iron (Liver extract)
N/A
Side Effects of Iron (Liver extract)
1. Nausea
2. Epigasttric distress
3. Vomiting
4. Constipation
5. Diarrhoea
6. Black stools
7. Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Liver extract)
1. Haemolytic anaemia
2. Haemochromatosis
3. Haemosiderosis
4. Peptic ulcer
5. Regional enteritis
6. Ulcerative colitis
7. Those receiving repeated blood transfusions
Special Precautions while taking Iron (Liver extract)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Liver extract)
1.Severe Nutritional anaemia
2.Macrocytic anaemia
3.Megaloblastic anaemia
4.Hepatitis
5.Liver cirrhosis
Interactions for Iron (Liver extract)
N/A
Typical Dosage for Iron (Liver extract)
As directed by the Physician
Schedule of Iron (Liver extract)
N/A
Storage Requirements for Iron (Liver extract)
N/A
Effects of Missed Dosage of Iron (Liver extract)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Liver extract)
Give supportive measures and symptomatic treatment.

Vit B6

About Vit B6
Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.
Mechanism of Action of Vit B6
Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.
Pharmacokinets of Vit B6
Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver
Onset of Action for Vit B6
N/A
Duration of Action for Vit B6
N/A
Half Life of Vit B6
15-20 days
Side Effects of Vit B6
1. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia
Contra-indications of Vit B6
1. Hypersensitivity to Vitamin B6
Special Precautions while taking Vit B6
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Vit B6
1. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning
Interactions for Vit B6
Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.
Typical Dosage for Vit B6
Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.
Schedule of Vit B6
N/A
Storage Requirements for Vit B6
Store it at 15 - 30 degree C. Protect from moisture and heat.
Effects of Missed Dosage of Vit B6
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B6
Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.

Vit B5

About Vit B5
Vitamin , A water-soluble B complex vitamin.
Mechanism of Action of Vit B5
Pantothenic acid exerts it`s actions by influencing metabolic reactions. It is a component of coenzyme-A which functions in carbohydrate, fat, steroid and porphyrin metabolism by catalyzing acetate transfer reactions.
Pharmacokinets of Vit B5
Absorption: Well absorbed orally.
Distribution: Widely distributed in the body tissues, and appears in the breast milk.
Excretion: 70% excreted unchanged in urine and 30% in faeces.
Onset of Action for Vit B5
N/A
Duration of Action for Vit B5
N/A
Half Life of Vit B5
N/A
Side Effects of Vit B5
N/A
Contra-indications of Vit B5
N/A
Special Precautions while taking Vit B5
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Vit B5
1. Nutritional supplement in conjunction with other B vitamins
2. Post operative paralytic ileus.
Interactions for Vit B5
Tetracycline: Vitamin B5 should not be taken at the same time as the Tetracycline because it interferes with the absorption and effectiveness of this medication.
B vitamins should be taken at different times from tetracycline.
Typical Dosage for Vit B5
Oral: 50 to 100mg daily.
Schedule of Vit B5
C1
Storage Requirements for Vit B5
Store in a well closed container; in a cool place and protect from light.
Effects of Missed Dosage of Vit B5
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B5
Provide symptomatic treatment and supportive measures.

Vit B3

About Vit B3
N/A
Mechanism of Action of Vit B3
Niacin refers to Nicotinic acid as well as Nicotinamide which exerts it`s action by influencing metabolic reactions. It is converted in to coenzymes Ncotinamide adenine dinucleotide (NAD) and it`s phosphate Ncotinamide adenine dinucleotide phosphate (NADP) involved in oxidation reduction reactions. These pyridine nucleotides act as hydrogen acceptors in the electron transport chain in tissue respiration, glycolysis, and fat synthesis. Nicotinic acid in high doses has vasodilator effects and also improves lipid profile; reduces serum cholesterol, raises HDL level, lowers VLDL, and LDL levels.
Pharmacokinets of Vit B3
Absorption: Well absorbed orally, Distribution: Widely distributed in the body, and also secreted in to breast milk, Modest amounts are stored in liver, Metabolism: Metabolized in to active metabolites in liver, Excretion: Extra drug is excreted through urine.
Onset of Action for Vit B3
N/A
Duration of Action for Vit B3
N/A
Half Life of Vit B3
N/A
Side Effects of Vit B3
1. Flushing
2. Activation of peptic ulcer
3. Nausea
4. Vomiting
5. Diarrhoea
6. Headache
7. Rashes
8. Pruritus
9. Hypotension
10. Arrhythmias
11. Hepatic impairment
Contra-indications of Vit B3
1. Hypersensitivity to the drug
2. Hepatic impairment
3. Peptic ulcer
4. Severe hypotension
5. Arterial haemorrhage
Special Precautions while taking Vit B3
1.History of liver disease
2.Gall bladder diseases
3.Gout
4.Coronary artery diseases
5.Diabetes mellitus
6.When use along with Statins reduces the dosage of Statins
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Vit B3
1. Pellagra
2. Niacin deficiency
3. Hartnup disease
4. Hyperlipidaemia (only nicotinic acid
5. Peripheral vascular diseases (only nicotinic acid)
Interactions for Vit B3
Aspirin: May decrease the metabolic clearance of nicotinic acid
Sympathetic blocking agent: May cause added vasodilation and hypotension
Isoniazid: may deplete levels of niacin and cause deficiency.
Typical Dosage for Vit B3
Oral:
Pellagra: 200 to 500mg daily in divided doses
Prophylactically: 20 to 50mg daily.
Dietary supplement: 10 to 20mg daily
Peripheral vascular diseases (only nicotinic acid): 100 to 150mg three to five times daily. Alternatively 1000 to 2000g once daily at bed time.
Hyperlipidaemia (only nicotinic acid): 1.5 to 6g daily in two to four divided doses with or after meals.
Hartnup disease: 50 to 200mg daily in divided doses.
Schedule of Vit B3
C1
Storage Requirements for Vit B3
Store at controlled room temperature at a range of 15 to 30 degree C
Effects of Missed Dosage of Vit B3
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B3
Provide supportive measures and symptomatic treatment

Vit B2

About Vit B2
N/A
Mechanism of Action of Vit B2
Riboflavin exerts it`s action by influencing metabolic reactions. Riboflavin functions in the forms of flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) which are coenzymes for flavoproteins involved in many oxidation-reduction reactions. Both FMN and FAD play a vital metabolic role in numerous tissue respiration systems. Riboflavin also directly involves in maintaining erythrocyte integrity.
Pharmacokinets of Vit B2
Absorption: Well absorbed orally; bioavailability increases when administer along with food.
Distribution: Widely distributed in the tissues and limited amount is stored in the liver, spleen, kidneys, and heart. It crosses the placenta and also secreted in to the breast milk.
Metabolism: Phosphorylated in the intestine, liver and other tissues to FMN and metabolized in to FAD the liver.
Excretion: Larger doses are excreted unchanged in urine.
Onset of Action for Vit B2
N/A
Duration of Action for Vit B2
N/A
Half Life of Vit B2
66 to 84 minutes
Side Effects of Vit B2
1. Bright yellow urine with higher doses
Contra-indications of Vit B2
No known contraindications.
Special Precautions while taking Vit B2
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Vit B2
1. Ariboflavinosis
2. Arteriosclerosis
3. Hypertension
4. Obesity
5. Diabetis
6. Cholepathy
7. Glossitis
8. Stomatitis
9. Dermatitis of trunk and extremities
10. Other riboflavin deficiency symptoms
Interactions for Vit B2
Oral contraceptive:Dose of Riboflavin may need to be increased
Propantheline Bromide:Delays absorption rate of Riboflavin
Typical Dosage for Vit B2
Oral:
Adults: 20 to 40mg three times daily or depending up on the severity.
Children: 20mg daily.
Riboflavin deficiency:
Adults and children over 12 years: 5 to 30mg/day depending up on the severity .
Children (below 12years): 3 to 10mg/day depending up on the severity.
Schedule of Vit B2
C1
Storage Requirements for Vit B2
Store in a well closed container; in a cool place and protect from light.
Effects of Missed Dosage of Vit B2
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose
Effects of Overdose of Vit B2
Provide symptomatic treatment and supportive measures.

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Iron (Ferric ammonium citrate) + Iron (Liver extract) + Vit B6 + Vit B5 + Vit B3 + Vit B2 is a generic medicine name and there are several brands available for it. Some of the brands for iron (ferric ammonium citrate) + iron (liver extract) + vit b6 + vit b5 + vit b3 + vit b2 might be better known than iron (ferric ammonium citrate) + iron (liver extract) + vit b6 + vit b5 + vit b3 + vit b2 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron (ferric ammonium citrate) + iron (liver extract) + vit b6 + vit b5 + vit b3 + vit b2 in stock, you can ask for one of the branded alternatives for iron (ferric ammonium citrate) + iron (liver extract) + vit b6 + vit b5 + vit b3 + vit b2.