- Medicine India
- Generic Medicines
- I
- Pharmacology For Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12
Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12 Pharmacology
Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12
About Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AMechanism of Action of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/APharmacokinets of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AOnset of Action for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/ADuration of Action for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AHalf Life of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/ASide Effects of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AContra-indications of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/ASpecial Precautions while taking Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AInteractions for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/ATypical Dosage for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/ASchedule of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AStorage Requirements for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AEffects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AEffects of Overdose of Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12N/AIron lll Hydroxide Polymaltose (IPC)
About Iron lll Hydroxide Polymaltose (IPC)It is a water soluble iron oxide, macro molecular complex of poly nuclear iron (III) hydroxide and partially hydrolysed dextrin (polymaltose).
Mechanism of Action of Iron lll Hydroxide Polymaltose (IPC)The absorption of ferric iron from IPC is controlled by a feedback mechanism. When IPC comes in contact with the iron binding sides at the mucosal surface, a physiological exchange is assumed to occur. IPC releases the required amount of ferric iron, which is actively transported into the mucosal cell by a carrier protein and from there released for binding to ferritin or transferrin.Pharmacokinets of Iron lll Hydroxide Polymaltose (IPC)N/AOnset of Action for Iron lll Hydroxide Polymaltose (IPC)N/ADuration of Action for Iron lll Hydroxide Polymaltose (IPC)N/AHalf Life of Iron lll Hydroxide Polymaltose (IPC)N/ASide Effects of Iron lll Hydroxide Polymaltose (IPC)There is a very low incidence of adverse effects. Occasionally gastrointestinal symptoms such as sensation of repletion, pressure in the epigastric reagion, nausea, constipation or diarrhoea can occur.Contra-indications of Iron lll Hydroxide Polymaltose (IPC)N/ASpecial Precautions while taking Iron lll Hydroxide Polymaltose (IPC)N/APregnancy Related InformationMay be used.Old Age Related InformationMay be used.Breast Feeding Related InformationMay be used.Children Related InformationN/AIndications for Iron lll Hydroxide Polymaltose (IPC)Treatment of latent iron deficiency and iron deficiency anaemia. Prevention of iron and folic acid deficiency before, during and after pregnancy. For prophylatic therapy of iron deficiency to cover the recommended daily dietary allowence during pregnancy and lactation.
Interactions for Iron lll Hydroxide Polymaltose (IPC)N/ATypical Dosage for Iron lll Hydroxide Polymaltose (IPC)Dosage and duration of therapy are dependent upon the extent of iron deficiency. It should be taken during or immediately after meals.Schedule of Iron lll Hydroxide Polymaltose (IPC)N/AStorage Requirements for Iron lll Hydroxide Polymaltose (IPC)Store at room temperature.Protect from heat and light.Keep out of the reach of children.Effects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC)Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Iron lll Hydroxide Polymaltose (IPC)Relatively non toxic. Provide symptomatic treatment and supportive measures.Folic Acid
About Folic AcidDietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.Mechanism of Action of Folic AcidFolic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.Pharmacokinets of Folic AcidAbsorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic AcidOral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic AcidOral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic AcidN/ASide Effects of Folic AcidN/AContra-indications of Folic AcidN/ASpecial Precautions while taking Folic Acid1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be usedIndications for Folic Acid1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic AcidOral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic AcidC1 (Oral)
C (Parenteral)
Storage Requirements for Folic AcidStore at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.Effects of Missed Dosage of Folic AcidTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Folic AcidRelatively non toxic. Provide symptomatic treatment and supportive measures.Vit B12
About Vit B12N/AMechanism of Action of Vit B12Vitamin B12 is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.Pharmacokinets of Vit B12Absorption: Absorbed irregularly after oral administration and absorption depends on Ca and intrinsic factor. It is also administered subcutaneously and intramuscularly.
Distribution: Distributed in to liver, bone marrow, and other tissues. It crosses the placenta and appears in breast milk.
Metabolism: It is metabolized in liver.
Excretion: In normal dosage it is reabsorbed from bile and a minute portion is excreted through urine but the extra drug is excreted through urine.
Onset of Action for Vit B12N/ADuration of Action for Vit B12N/AHalf Life of Vit B12N/ASide Effects of Vit B121. Anaphylaxis
2. Anaphylactoid reactions
3. Pain and burning sensation at injection site
4. Itching
5. Urticaria
6. Transient diarrhea
7. Peripheral vascular thrombosis
8. Pulmonary oedema
Contra-indications of Vit B121. Hypersensitivity to the drug
2. Leber`s disease
Special Precautions while taking Vit B121. Anemic patients with coexisting cardiac, pulmonary and hypertensive diseases.Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationUse with caution
NEONATES : Use with caution
Indications for Vit B121. Vitamin B12 deficiency
2. Pernicious Anaemia
3. Peripheral neuropathy (diabetic, alcoholic, and drug induced)
Interactions for Vit B12N/ATypical Dosage for Vit B12I.M., S.C.:
Pernicious Anaemia: 100mcg daily for 1 week followed by the same dose given on alternate days for 7 doses and then every 3 to 4days for another 3 weeks. This regimen should be followed by 100mcg monthly for life. Concurrently administer folic acid if required.
Vitamin B12 deficiency other than pernicious Anaemia: 30mcg daily for 5 to 10days depending up on the severity of the condition.
Maintenance dosage: 100 to 200mcg once monthly.
Children: 100mcg I.M. or S.C. over the course of 2 or more weeks.
Maintenance dosage: 60mcg monthly I.M. or S.C.
Schilling test flushing dose:
Adults and Children: 1000mcg I.M. in single dose
Recommended RDA (recommended dietary allowance) for Vitamin B12:
Infants up to 6months of age: 0.3mcg.
Children age 6 months to 1 year: 0.5mcg.
Children age 1 to 3: 0.7mcg.
Children age 4 to 6: 1mcg.
Children age 7 to 10: 1.4mcg.
Children age 11 to adult: 2mcg..
Pregnant women: 2.2mcg.
Breast feeding women: 2.6mcg.
Schedule of Vit B12CStorage Requirements for Vit B12Store at room temperature range of 15 to 30 degree C.in a light resistant well closed container in a dry place.Effects of Missed Dosage of Vit B12Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vit B12Not applicable. Even in large doses Vitamin B12 isn`t usually toxic.Home Delivery for Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12 in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including iron lll hydroxide polymaltose (ipc) + folic acid + vit b12.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 and other medicines and health products. Home delivery services for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 before they complete the sale. You can get this information while placing the order for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 with the pharmacy.
Iron lll Hydroxide Polymaltose (IPC) + Folic acid + Vit B12 is a generic medicine name and there are several brands available for it. Some of the brands for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 might be better known than iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron lll hydroxide polymaltose (ipc) + folic acid + vit b12 in stock, you can ask for one of the branded alternatives for iron lll hydroxide polymaltose (ipc) + folic acid + vit b12.
