Distribution- Widely distributed in the body. Drug and its metabolites not bound to the plasma proteins
Metabolism- It is metabolized in the liver by the enzyme xanthine oxidase. Oxypurinol is its active metabolite
Excretion- Excreted via urine and feces (as unchanged and metabolites form)
4. Skin rash.
5. Painful urination.
6. Blood in the urine.
7. Irritation of the eyes.
8. Swelling of the lips or mouth.
10. Sore throat.
12. Loss of appetite.
13. Unexpected weight loss.
2. Acute gout.
2. Renal dysfunction.
3. Any work which require mental alertness such as driving and operating machine.
2. Secondary hyperuricaemia due to myeloid metaplasia, radiation, cancer chemotherapy, thiazide diuretics.
3. Prevention of uric acid nephropathy.
Oral hypoglycemic Agents: Enhanced activity.
Anticoagulants: Enhanced activity.
Thiopurines (Azothioprine & Mercaptopurine): Clinically significant increase in pharmacologic and toxic effects.
Uricosuric Agents (Probenecid): Enhance urinary excretion of Allopurinol.
Cyclophosphamide: Myelosuppressive effect of cyclophosphamide enhanced.
Thiazide Derivatives: Increase in hypersensitivity reactions to Allopurinol.
Ampicillin: Increase in ampicillin induced skin rash.
Salicylates: Enhance urinary excretion of allopurinol.
Initial dose: 100 - 200 mg daily
Maintenance dose: 200-800 mg daily
Home Delivery for Allopurinol in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including allopurinol.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for allopurinol and other medicines and health products. Home delivery services for allopurinol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take allopurinol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for allopurinol before they complete the sale. You can get this information while placing the order for allopurinol with the pharmacy.
Allopurinol is a generic medicine name and there are several brands available for it. Some of the brands for allopurinol might be better known than allopurinol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have allopurinol in stock, you can ask for one of the branded alternatives for allopurinol.