Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6 Pharmacology

Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6

About Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Mechanism of Action of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Pharmacokinets of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Onset of Action for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Duration of Action for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Half Life of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Side Effects of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Contra-indications of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Special Precautions while taking Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Interactions for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Typical Dosage for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Schedule of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Storage Requirements for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Effects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A
Effects of Overdose of Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6
N/A

Iron lll Hydroxide Polymaltose (IPC)

About Iron lll Hydroxide Polymaltose (IPC)
It is a water soluble iron oxide, macro molecular complex of poly nuclear iron (III) hydroxide and partially hydrolysed dextrin (polymaltose).
Mechanism of Action of Iron lll Hydroxide Polymaltose (IPC)
The absorption of ferric iron from IPC is controlled by a feedback mechanism. When IPC comes in contact with the iron binding sides at the mucosal surface, a physiological exchange is assumed to occur. IPC releases the required amount of ferric iron, which is actively transported into the mucosal cell by a carrier protein and from there released for binding to ferritin or transferrin.
Pharmacokinets of Iron lll Hydroxide Polymaltose (IPC)
N/A
Onset of Action for Iron lll Hydroxide Polymaltose (IPC)
N/A
Duration of Action for Iron lll Hydroxide Polymaltose (IPC)
N/A
Half Life of Iron lll Hydroxide Polymaltose (IPC)
N/A
Side Effects of Iron lll Hydroxide Polymaltose (IPC)
There is a very low incidence of adverse effects. Occasionally gastrointestinal symptoms such as sensation of repletion, pressure in the epigastric reagion, nausea, constipation or diarrhoea can occur.
Contra-indications of Iron lll Hydroxide Polymaltose (IPC)
N/A
Special Precautions while taking Iron lll Hydroxide Polymaltose (IPC)
N/A
Pregnancy Related Information
May be used.
Old Age Related Information
May be used.
Breast Feeding Related Information
May be used.
Children Related Information
N/A
Indications for Iron lll Hydroxide Polymaltose (IPC)
Treatment of latent iron deficiency and iron deficiency anaemia. Prevention of iron and folic acid deficiency before, during and after pregnancy. For prophylatic therapy of iron deficiency to cover the recommended daily dietary allowence during pregnancy and lactation.
Interactions for Iron lll Hydroxide Polymaltose (IPC)
N/A
Typical Dosage for Iron lll Hydroxide Polymaltose (IPC)
Dosage and duration of therapy are dependent upon the extent of iron deficiency. It should be taken during or immediately after meals.
Schedule of Iron lll Hydroxide Polymaltose (IPC)
N/A
Storage Requirements for Iron lll Hydroxide Polymaltose (IPC)
Store at room temperature.Protect from heat and light.Keep out of the reach of children.
Effects of Missed Dosage of Iron lll Hydroxide Polymaltose (IPC)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron lll Hydroxide Polymaltose (IPC)
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Vit B12

About Vit B12
N/A
Mechanism of Action of Vit B12
Vitamin B12 is an essential constituent for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Vitamin B12 is converted in to coenzyme B12 in the tissues which is essential for conversion of methyl-malonate to succinate and synthesis of methionine from homocystine. It is also associated with fat and carbohydrate metabolism and protein synthesis. Cells characterized by rapid division such as epithelial cells, bone marrow, and myeloid cells appear to have greatest requirement of Cyanocobalamin.
Pharmacokinets of Vit B12
Absorption: Absorbed irregularly after oral administration and absorption depends on Ca and intrinsic factor. It is also administered subcutaneously and intramuscularly.
Distribution: Distributed in to liver, bone marrow, and other tissues. It crosses the placenta and appears in breast milk.
Metabolism: It is metabolized in liver.
Excretion: In normal dosage it is reabsorbed from bile and a minute portion is excreted through urine but the extra drug is excreted through urine.
Onset of Action for Vit B12
N/A
Duration of Action for Vit B12
N/A
Half Life of Vit B12
N/A
Side Effects of Vit B12
1. Anaphylaxis
2. Anaphylactoid reactions
3. Pain and burning sensation at injection site
4. Itching
5. Urticaria
6. Transient diarrhea
7. Peripheral vascular thrombosis
8. Pulmonary oedema
Contra-indications of Vit B12
1. Hypersensitivity to the drug
2. Leber`s disease
Special Precautions while taking Vit B12
1. Anemic patients with coexisting cardiac, pulmonary and hypertensive diseases.
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
NEONATES : Use with caution
Indications for Vit B12
1. Vitamin B12 deficiency
2. Pernicious Anaemia
3. Peripheral neuropathy (diabetic, alcoholic, and drug induced)
Interactions for Vit B12
N/A
Typical Dosage for Vit B12
I.M., S.C.:
Pernicious Anaemia: 100mcg daily for 1 week followed by the same dose given on alternate days for 7 doses and then every 3 to 4days for another 3 weeks. This regimen should be followed by 100mcg monthly for life. Concurrently administer folic acid if required.
Vitamin B12 deficiency other than pernicious Anaemia: 30mcg daily for 5 to 10days depending up on the severity of the condition.
Maintenance dosage: 100 to 200mcg once monthly.
Children: 100mcg I.M. or S.C. over the course of 2 or more weeks.
Maintenance dosage: 60mcg monthly I.M. or S.C.
Schilling test flushing dose:
Adults and Children: 1000mcg I.M. in single dose
Recommended RDA (recommended dietary allowance) for Vitamin B12:
Infants up to 6months of age: 0.3mcg.
Children age 6 months to 1 year: 0.5mcg.
Children age 1 to 3: 0.7mcg.
Children age 4 to 6: 1mcg.
Children age 7 to 10: 1.4mcg.
Children age 11 to adult: 2mcg..
Pregnant women: 2.2mcg.
Breast feeding women: 2.6mcg.
Schedule of Vit B12
C
Storage Requirements for Vit B12
Store at room temperature range of 15 to 30 degree C.in a light resistant well closed container in a dry place.
Effects of Missed Dosage of Vit B12
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B12
Not applicable. Even in large doses Vitamin B12 isn`t usually toxic.

Vit B6

About Vit B6
Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.
Mechanism of Action of Vit B6
Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.
Pharmacokinets of Vit B6
Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver
Onset of Action for Vit B6
N/A
Duration of Action for Vit B6
N/A
Half Life of Vit B6
15-20 days
Side Effects of Vit B6
1. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia
Contra-indications of Vit B6
1. Hypersensitivity to Vitamin B6
Special Precautions while taking Vit B6
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Vit B6
1. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning
Interactions for Vit B6
Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.
Typical Dosage for Vit B6
Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.
Schedule of Vit B6
N/A
Storage Requirements for Vit B6
Store it at 15 - 30 degree C. Protect from moisture and heat.
Effects of Missed Dosage of Vit B6
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B6
Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.

Home Delivery for Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6 in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 and other medicines and health products. Home delivery services for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 before they complete the sale. You can get this information while placing the order for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 with the pharmacy.

Iron lll Hydroxide Polymaltose (IPC) + Vit B12 + Vit B6 is a generic medicine name and there are several brands available for it. Some of the brands for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 might be better known than iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6 in stock, you can ask for one of the branded alternatives for iron lll hydroxide polymaltose (ipc) + vit b12 + vit b6.