Iron (Ferrous gluconate) Pharmacology

Iron (Ferrous gluconate)

About Iron (Ferrous gluconate)
Oral iron preparation, iron(II) salt of gluconic acid, Antianemic,hematinic.
Mechanism of Action of Iron (Ferrous gluconate)
Ferrous gluconate is used as a source of iron for iron-deficiency anaemia. It is given by mouth in doses of up to 1.8 g daily (equivalent to up to 210 mg of iron daily). Iron formulations exert haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Ferrous gluconate)
Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed. Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin. Metabolism: Iron liberated by destruction of haemoglobin is reused by the body. Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Ferrous gluconate)
N/A
Duration of Action for Iron (Ferrous gluconate)
N/A
Half Life of Iron (Ferrous gluconate)
N/A
Side Effects of Iron (Ferrous gluconate)
1.Nausea
2.Epigasttric distress
3.Vomiting
4.Constipation
5.Diarrhoea
6.Black stools
7.Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Ferrous gluconate)
1.Haemolytic anaemia unless iron deficiency anaemia is also present
2.Haemochromatosis
3.Haemosiderosis
4.Peptic ulcer
5.Regional enteritis
6.Ulcerative colitis
7.Those receiving repeated blood transfusions.
Special Precautions while taking Iron (Ferrous gluconate)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Ferrous gluconate)
1. Iron deficiency
2. Iron deficiency anaemia
Interactions for Iron (Ferrous gluconate)
N/A
Typical Dosage for Iron (Ferrous gluconate)
Oral:
Ferrous gluconate:
300 to 1200mg daily in three to four divided doses.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Schedule of Iron (Ferrous gluconate)
H
Storage Requirements for Iron (Ferrous gluconate)
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Iron (Ferrous gluconate)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Ferrous gluconate)
Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

Home Delivery for Iron (Ferrous gluconate) in Your City

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Iron (Ferrous gluconate) is a generic medicine name and there are several brands available for it. Some of the brands for iron (ferrous gluconate) might be better known than iron (ferrous gluconate) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have iron (ferrous gluconate) in stock, you can ask for one of the branded alternatives for iron (ferrous gluconate).