Chromium Pharmacology


About Chromium
Chromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.

Mechanism of Action of Chromium
Chromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.
Pharmacokinets of Chromium
Absorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.
Onset of Action for Chromium
Duration of Action for Chromium
Half Life of Chromium
Side Effects of Chromium
Contra-indications of Chromium
1. Hypersensitivity to the drug.
Special Precautions while taking Chromium
1. Prolonged therapy with the drug
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Chromium
1.Type I diabetes mellitus
2.Type II diabetes mellitus
Interactions for Chromium
Typical Dosage for Chromium
Oral: 200 mcg daily; increases up to 1mg daily if required.
Schedule of Chromium
Storage Requirements for Chromium
Store in a well closed container at a cool dry place.
Effects of Missed Dosage of Chromium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Chromium
Give supportive measures and symptomatic treatment.

Home Delivery for Chromium in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including chromium.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for chromium and other medicines and health products. Home delivery services for chromium may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take chromium only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for chromium before they complete the sale. You can get this information while placing the order for chromium with the pharmacy.

Chromium is a generic medicine name and there are several brands available for it. Some of the brands for chromium might be better known than chromium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have chromium in stock, you can ask for one of the branded alternatives for chromium.