Chromium + Copper + Manganese + Zinc + Selenium Pharmacology

Chromium + Copper + Manganese + Zinc + Selenium

About Chromium + Copper + Manganese + Zinc + Selenium
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Mechanism of Action of Chromium + Copper + Manganese + Zinc + Selenium
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Pharmacokinets of Chromium + Copper + Manganese + Zinc + Selenium
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Onset of Action for Chromium + Copper + Manganese + Zinc + Selenium
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Duration of Action for Chromium + Copper + Manganese + Zinc + Selenium
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Half Life of Chromium + Copper + Manganese + Zinc + Selenium
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Side Effects of Chromium + Copper + Manganese + Zinc + Selenium
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Contra-indications of Chromium + Copper + Manganese + Zinc + Selenium
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Special Precautions while taking Chromium + Copper + Manganese + Zinc + Selenium
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Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Chromium + Copper + Manganese + Zinc + Selenium
1.Supplement to IV parenteral nutrition solution
2.Deficiency of trace elements
Interactions for Chromium + Copper + Manganese + Zinc + Selenium
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Typical Dosage for Chromium + Copper + Manganese + Zinc + Selenium
As directed by the Physician
Schedule of Chromium + Copper + Manganese + Zinc + Selenium
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Storage Requirements for Chromium + Copper + Manganese + Zinc + Selenium
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Effects of Missed Dosage of Chromium + Copper + Manganese + Zinc + Selenium
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Effects of Overdose of Chromium + Copper + Manganese + Zinc + Selenium
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Chromium

About Chromium
Chromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.

Mechanism of Action of Chromium
Chromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.
Pharmacokinets of Chromium
Absorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.
Onset of Action for Chromium
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Duration of Action for Chromium
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Half Life of Chromium
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Side Effects of Chromium
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Contra-indications of Chromium
1. Hypersensitivity to the drug.
Special Precautions while taking Chromium
1. Prolonged therapy with the drug
2.Hypoglycaemia
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Chromium
1.Type I diabetes mellitus
2.Type II diabetes mellitus
3.Obesity.
Interactions for Chromium
N/A
Typical Dosage for Chromium
Oral: 200 mcg daily; increases up to 1mg daily if required.
Schedule of Chromium
N/A
Storage Requirements for Chromium
Store in a well closed container at a cool dry place.
Effects of Missed Dosage of Chromium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Chromium
Give supportive measures and symptomatic treatment.

Copper

About Copper
Third most abundant essential trace mineral, A cofactor for many proteins, iron utilization enhancer, Copper deficiency.
Mechanism of Action of Copper
Copper is one of a relatively small group of metallic elements which are essential to human health. These elements, along with amino and fatty acids as well as vitamins, are required for normal metabolic processes.
Pharmacokinets of Copper
Absorption:It is orally well absorbed.
Onset of Action for Copper
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Duration of Action for Copper
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Half Life of Copper
N/A
Side Effects of Copper
1.Breathing problems
2.Chest pain
3.Skin hives
4.Rash
5.Swollen skin
6.Upset stomach
Contra-indications of Copper
Hypersensitivity to the drug
Special Precautions while taking Copper
1.Blood pressure
2.Heart or blood vessel disease
Pregnancy Related Information
use with caution
Old Age Related Information
N/A
Breast Feeding Related Information
use with caution
Children Related Information
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Indications for Copper
1. As a supplement for the prevention of cardiovascular disease, anemia, to enhance immunity, and to treat arthritis.
Interactions for Copper
N/A
Typical Dosage for Copper
As directed by the physician
Schedule of Copper
N/A
Storage Requirements for Copper
Store at 15 - 30 degree C. Protect from heat and light. Kept the container tightly closed after use. Keep out of the reach of children
Effects of Missed Dosage of Copper
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Copper
Give supportive measures and symptomatic treatment.

Manganese

About Manganese
Magnesium is essential for enzyme activity, calcium and potassium uptake, nerve transmission, bone formation and metabolism of carbohydrates and minerals. It is magnesium, not calcium, which helps form hard tooth enamel, resistant to decay. Like calcium and chloride, magnesium also plays a role in regulating the acid-alkaline balance in the body. High magnesium levels in drinking water have been linked to resistance to heart disease. Although it is found in many foods, including dairy products, nuts, vegetables, fish, meat and seafood, deficiencies are common in America due to soil depletion, poor absorption and lack of minerals in drinking water. A diet high in carbohydrates, oxalic acid in foods like raw spinach and phytic acid found in whole grains can cause deficiencies. An excellent source of usable magnesium is beef, chicken or fish broth. High amounts of zinc and vitamin D increase magnesium requirements. Magnesium deficiency can result in coronary heart disease, chronic weight loss, obesity, fatigue, epilepsy and impaired brain function. Chocolate cravings are a sign of magnesium deficiency.
Mechanism of Action of Manganese
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Pharmacokinets of Manganese
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Onset of Action for Manganese
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Duration of Action for Manganese
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Half Life of Manganese
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Side Effects of Manganese
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Contra-indications of Manganese
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Special Precautions while taking Manganese
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Manganese
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Interactions for Manganese
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Typical Dosage for Manganese
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Schedule of Manganese
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Storage Requirements for Manganese
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Effects of Missed Dosage of Manganese
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Effects of Overdose of Manganese
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Zinc

About Zinc
Trance metal, Dietary mineral, Nutritional supplement,Treatment of zinc deficiency,in wound healing.
Mechanism of Action of Zinc
Zinc acts as a cofactor for more than 70 different enzymes. Zinc dependent enzymes are involved in the metabolism of carbohydrates, lipids, and proteins. Zinc facilitates wound healing, normal growth rates, normal skin hydration and maintains senses of taste and smell. It provides normal growth and tissue repair. It also helps in development of cell mediated immunity.
Pharmacokinets of Zinc
Absorption: Poorly absorbed orally, Distribution: Zinc is distributed mainly in to skeletal muscle, skin, bone, pancreas, kidney, liver, retina, prostate, RBC, and WBC. Excretion: Excreted mainly through intestine; only 2% loss in the urine.
Onset of Action for Zinc
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Duration of Action for Zinc
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Half Life of Zinc
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Side Effects of Zinc
1. Nausea
2. Vomiting
3. Abdominal distress
4. Gastric ulceration
5. Rashes
Contra-indications of Zinc
N/A
Special Precautions while taking Zinc
1.Don`t exceed prescribed dose
2.Renal failure
3.Biliary obstruction

Pregnancy Related Information
Use with caution
Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc
1. Zinc deficiency
2. Acne vulgaris
3. Chronic skin ulcers
4. Adjunct to antimicrobials
5. Delayed wound healing
6. Alopecia
Interactions for Zinc
Fluoroquinolones, Tetracyclines: Decreased GI absorption and serum levels of some fluoroquinolone.
Pencillamine: Reduced absorption of zinc.
Iron: Reduced absorption of iron and vice versa.

Typical Dosage for Zinc
Adults: 25 to 50mg zinc daily or 1 to 2 tablets daily.
Children: 5mg/kg 1 to 3 times daily.
Schedule of Zinc
N/A
Storage Requirements for Zinc
Store at a temperature below 30 degree C
Effects of Missed Dosage of Zinc
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Zinc
Provide symptomatic treatment and supportive measures

Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
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Pharmacokinets of Selenium
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Onset of Action for Selenium
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Duration of Action for Selenium
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Half Life of Selenium
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Side Effects of Selenium
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Contra-indications of Selenium
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Special Precautions while taking Selenium
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Selenium
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Interactions for Selenium
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Typical Dosage for Selenium
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Schedule of Selenium
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Storage Requirements for Selenium
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Effects of Missed Dosage of Selenium
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Effects of Overdose of Selenium
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Home Delivery for Chromium + Copper + Manganese + Zinc + Selenium in Your City

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