Co Enzyme Q10 Pharmacology

Co Enzyme Q10

About Co Enzyme Q10
1,4-benzoquinone derivative, oil-soluble vitamin-like substance, Enzyme cofactors, powerful antioxidant
Mechanism of Action of Co Enzyme Q10
Coenzyme Q10 is vital for the proper transfer of electrons within the mitochondrial oxidative respiratory chain there it passes reducing equivalents to acceptors such as Coenzyme Q: cytochrome c - oxidoreductase:
CoQH2+ 2 FeIII-cytochrome c ? CoQ + 2 FeII-cytochrome c. main function of this transport is adenosine triphosphate production. Coenzyme Q10 also increases adenosine triphosphate levels by preventing the loss of the adenine nucleotide pool from cardiac cells. Coenzyme Q10 has activity as an antioxidant scavenger and an indirect stabilizer of calcium channels to decrease calcium overload. It also inhibits the oxidation of LDL-cholesterol. LDL-cholesterol oxidation is believed to play a significant role in the pathogenesis of atherosclerosis.
Pharmacokinets of Co Enzyme Q10
Absorption- Poorly absorbed after oral administration. Excretion- Excreted through bile and feces
Onset of Action for Co Enzyme Q10
Duration of Action for Co Enzyme Q10
Half Life of Co Enzyme Q10
Side Effects of Co Enzyme Q10
1. Nausea
2. Vomiting
3. Stomach upset
4. Heartburn
5. Diarrhea
6. Loss of appetite
7. Skin itching
8. Rash
9. Insomnia
10. Headache
11. Dizziness
12. Irritability
13. Increased light sensitivity of the eyes
14. Fatigue
15. Flu-like symptoms
Contra-indications of Co Enzyme Q10
Special Precautions while taking Co Enzyme Q10
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Co Enzyme Q10
1. Dietary supplement
2. Antioxidant
3. Migraine headaches
4. Parkinson`s Disease
5. Mitochondrial Encephalomyopathies
6. Migraine
7. CHF
8. Hypertension
9. Diabetes
10. Cancer
Interactions for Co Enzyme Q10
Typical Dosage for Co Enzyme Q10
Mitochondrial cytopathies: 150 mg per day or 2 mg per kg per day with titration up to 3,000 mg per day in some patients
Parkinson`s disease: 300 to 1,200 mg per day in four divided doses
Cardiovascular problems: 50 to 200 mg per day
Migraine 100 to 200 mg per day
Schedule of Co Enzyme Q10
Storage Requirements for Co Enzyme Q10
Keep tightly closed in a dry place. Do not expose to excessive heat.
Effects of Missed Dosage of Co Enzyme Q10
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.Do not double the dose.Continue the regular schedule.
Effects of Overdose of Co Enzyme Q10
Give supportive measures and symptomatic treatment.

Home Delivery for Co Enzyme Q10 in Your City

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Please be aware that you should take co enzyme q10 only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for co enzyme q10 before they complete the sale. You can get this information while placing the order for co enzyme q10 with the pharmacy.

Co Enzyme Q10 is a generic medicine name and there are several brands available for it. Some of the brands for co enzyme q10 might be better known than co enzyme q10 itself. If the pharmacy that's willing to deliver medicines to your home doesn't have co enzyme q10 in stock, you can ask for one of the branded alternatives for co enzyme q10.