Gamma linolenic acid Pharmacology

Gamma linolenic acid

About Gamma linolenic acid

An essential Fatty acid(omega-6 family), A dietary supplement with antiinflammatory.

Mechanism of Action of Gamma linolenic acid

GLA is metabolized to the 20-carbon polyunsaturated fatty acid DGLA, which is cyclooxygenated to prostaglandin E1 (PGE1). PGE1 elicits biologic activities by binding to surface receptors on smooth muscle cells, increasing intracellular cAMP.
GLA, via conversion to PGE1, exhibits anti-inflammatory, antithrombotic, antiproliferative, and lipid-lowering potential. It also enhances smooth muscle relaxation and vasodilation. In addition, EFAs including GLA are important constituents of membrane phospholipids, including the mitochondrial membrane, where they enhance the integrity and the fluidity of the membrane. Studies have shown that GLA has a role in management of Dry eye, Atopic eczema and cyclical mastalgia (pre-menstrual breast pain).

Pharmacokinets of Gamma linolenic acid

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Onset of Action for Gamma linolenic acid

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Duration of Action for Gamma linolenic acid

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Half Life of Gamma linolenic acid

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Side Effects of Gamma linolenic acid

1.Upset stomach
2.Diarrhea
3.Soft stool
4.Bloating
5.Gas

Contra-indications of Gamma linolenic acid

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Special Precautions while taking Gamma linolenic acid

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Gamma linolenic acid

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Interactions for Gamma linolenic acid

1.Phenothiazines and anticonvulsants due to an increased incidence of seizures.
2.Even though no cases are known of interaction with anticoagulant medications, it may be prudent to closely monitor concomitant usage.
3.Gamma Linolenic acid is shown to reduce tremors from lithium use in manic depressives.

Typical Dosage for Gamma linolenic acid

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Schedule of Gamma linolenic acid

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Storage Requirements for Gamma linolenic acid

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Effects of Missed Dosage of Gamma linolenic acid

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Effects of Overdose of Gamma linolenic acid

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Home Delivery for Gamma linolenic acid in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including gamma linolenic acid.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for gamma linolenic acid and other medicines and health products. Home delivery services for gamma linolenic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take gamma linolenic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for gamma linolenic acid before they complete the sale. You can get this information while placing the order for gamma linolenic acid with the pharmacy.

Gamma linolenic acid is a generic medicine name and there are several brands available for it. Some of the brands for gamma linolenic acid might be better known than gamma linolenic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have gamma linolenic acid in stock, you can ask for one of the branded alternatives for gamma linolenic acid.