- Medicine India
- Generic Medicines
- V
- Pharmacology For Vitamin E + L-carnitine
Vitamin E + L-carnitine Pharmacology
Vitamin E + L-carnitine
About Vitamin E + L-carnitineN/AMechanism of Action of Vitamin E + L-carnitineN/APharmacokinets of Vitamin E + L-carnitineN/AOnset of Action for Vitamin E + L-carnitineN/ADuration of Action for Vitamin E + L-carnitineN/AHalf Life of Vitamin E + L-carnitineN/ASide Effects of Vitamin E + L-carnitineN/AContra-indications of Vitamin E + L-carnitineN/ASpecial Precautions while taking Vitamin E + L-carnitineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Vitamin E + L-carnitineN/AInteractions for Vitamin E + L-carnitineN/ATypical Dosage for Vitamin E + L-carnitineN/ASchedule of Vitamin E + L-carnitineN/AStorage Requirements for Vitamin E + L-carnitineN/AEffects of Missed Dosage of Vitamin E + L-carnitineN/AEffects of Overdose of Vitamin E + L-carnitineN/AVitamin E
About Vitamin EN/AMechanism of Action of Vitamin EVitamin E acts as an antioxidant and protecting unsaturated lipids in the cell membrane, coenzyme Q, vitamin A, vitamin C etc. from free radical oxidation damage and generation of toxic peroxidation products. It also decreases platelet aggregation.Pharmacokinets of Vitamin EAbsorption: Absorbed through lymph with the help of bile. Only 20 to 60% of vitamin from dietary sources is absorbed. As dose increases the fraction absorbed decreases.
Distribution: Widely distributed in a protein bound form and stored in adipose tissue.
Metabolism: Metabolized in liver by glucuronide conjugation.
Excretion: Excreted mainly through bile and also excreted through urine.
Onset of Action for Vitamin EN/ADuration of Action for Vitamin EN/AHalf Life of Vitamin EN/ASide Effects of Vitamin E1. Fatigue
2. Weakness
3. Headache
4. Nausea
5. Diarrhoea
6. Blurred vision
7. Flatulence
Contra-indications of Vitamin E1. Hypersensitivity to the drug
2. Should not administer intravenously
Special Precautions while taking Vitamin E1. Hepatic impairment
2. Gall bladder disease
3. Along with estrogens
Pregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Vitamin E1. Vitamin E deficiency
2. Intermittent claudication
3. Nocturnal muscle cramps
4. Coronary artery disease
5. Fibrocystic breast disease
6. Cystic fibrosis
7. In premature infants exposed to high concentration of oxygen
8. As antioxidant
Interactions for Vitamin EOral anticoagulants : Hypoprothrombinemic effect may be increased with possibility of bleeding.
Typical Dosage for Vitamin EOral:
Vitamin E deficiency:
Adults: 40 to 50mg/day or 60 to 75i.u. daily based on the severity of deficiency.
Children: 1 unit/kg/day.
Premature neonates: 5units daily.
Full term neonates: 5 units per liter of formula.
Intermittent claudication: 400mg/day for 12 to 18 weeks.
Nocturnal muscle cramps: 400mg/day for 8 to 12 weeks.
Coronary artery disease: 100 to 200mg/day for at least 2 years.
Fibrocystic breast disease: 600mg/day for at least 2years.
Cystic fibrosis: 100 to 200mg/day.
Children above 1 year: 100mg/day.
Children below 1year: 50mg/day.
Schedule of Vitamin EC1Storage Requirements for Vitamin EStore in a well closed container in a cool dry place. Protect from light.Effects of Missed Dosage of Vitamin ETake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Vitamin EProvide supportive measures and symptomatic treatment.L-carnitine
About L-carnitineDietary supplement, Amino acid derivative, Antioxidant.Mechanism of Action of L-carnitineCarnitine is an essential co-factor of fatty acid metabolism in the heart, liver, and skeletal muscle. It is normally synthesised in the liver, brain, and kidneys in sufficient quantities to meet human requirements. It is an antioxidant. It protects neurons from damage caused by super oxide radicals.Pharmacokinets of L-carnitineLevocarnitine is absorbed slowly and incompletely from the small intestine. Distribution: It is distributed mainly in free form. Metabolism: It undergoes minimal metabolism. Excretion: It is excreted mainly in urine and small amount through faeces.Onset of Action for L-carnitineN/ADuration of Action for L-carnitineN/AHalf Life of L-carnitineN/ASide Effects of L-carnitine1.Nausea
2.Vomiting
3.Diarrhoea
4.Abdominal cramps
Contra-indications of L-carnitineN/ASpecial Precautions while taking L-carnitine1.Severe renal impairment
2.Diabetic patients
Pregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for L-carnitine1.As antioxidant
2.Carnitine deficiency
Interactions for L-carnitineN/ATypical Dosage for L-carnitineOral
Adult: 100 - 200 mg/kg daily in 2 to 4 divided doses.
Children: 50 to 100 mg/kg daily in 2 to 4 divided doses
Parenteral (IV)
Adult: 50 to 100 mg/kg daily is given in 3 to 4 divided doses by slow intravenous injection over 2 to 3 minutes.
Schedule of L-carnitineHStorage Requirements for L-carnitineN/AEffects of Missed Dosage of L-carnitineN/AEffects of Overdose of L-carnitineN/AHome Delivery for Vitamin E + L-carnitine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including vitamin e + l-carnitine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for vitamin e + l-carnitine and other medicines and health products. Home delivery services for vitamin e + l-carnitine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take vitamin e + l-carnitine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for vitamin e + l-carnitine before they complete the sale. You can get this information while placing the order for vitamin e + l-carnitine with the pharmacy.
Vitamin E + L-carnitine is a generic medicine name and there are several brands available for it. Some of the brands for vitamin e + l-carnitine might be better known than vitamin e + l-carnitine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have vitamin e + l-carnitine in stock, you can ask for one of the branded alternatives for vitamin e + l-carnitine.
