Sodium fluoride Mouth Wash Pharmacology

Sodium fluoride Mouth Wash

About Sodium fluoride Mouth Wash
Topical teeth preparation, Fluorides, Prophylaxis of dental caries.
Mechanism of Action of Sodium fluoride Mouth Wash
Sodium fluoride increases osteoblast activity and increase bone volume. Adequate incorporation of fluoride into teeth hardens the outer layers of enamel and increases resistances to demineralization. (The bacteria that cause caries produce acid through the fermentation of carbohydrates, which can dissolve the carbonated hydroxyapatite mineral of teeth, a process called demineralization).
Sodium fluoride acts systemically (before tooth eruption) and topically (post eruption) by increasing tooth resistance to acid dissolution, by promoting remineralization, by inhibiting the cariogenic microbial process and by inhibiting bacterial enzymes. Incorporation of fluoride into apatite crystals reduces the dissolution of apatite during acid attacks. Fluoride interacts with hydroxyapatite to form the less acid soluble fluorhydroxyapatite. Fluorhydroxyapatite is more resistant to dissolution by the acids produced by bacteria found in plaque. Fluoride may also promote the remineralization of enamel in early caries. Finally fluoride may reduce oral concentrations of cariogenic bacteria or reduce the metabolism of bacteria in plaque.
Pharmacokinets of Sodium fluoride Mouth Wash
Pharmaco Kinetic
Absorption: Sodium fluoride is well absorbed after oral administration.
Distribution: It is widely distributed in body tissues and organs and concentrated mainly in the teeth and bone.
Excretion: It is excreted mainly in the urine. Small amount is also excreted in sweat, milk and intestinal secretions.
Onset of Action for Sodium fluoride Mouth Wash
N/A
Duration of Action for Sodium fluoride Mouth Wash
N/A
Half Life of Sodium fluoride Mouth Wash
N/A
Side Effects of Sodium fluoride Mouth Wash
1. Gastric distress
2. Staining of teeth
3. Eczema
4. Urticaria
5. Atopic dermatitis
Contra-indications of Sodium fluoride Mouth Wash
1. Hypersensitivity to Sodium fluoride
2. Fluoride content in water is more than 0.6 ppm
Special Precautions while taking Sodium fluoride Mouth Wash
Do not eat, drink or rinse mouth for 15 - 30 minutes after application.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Sodium fluoride Mouth Wash
1. Dental caries
Interactions for Sodium fluoride Mouth Wash
N/A
Typical Dosage for Sodium fluoride Mouth Wash
Adult: 3 - 4 mg / day
Oral solutions (Sodium fluoride 0.2%fluoride ion) Rinse the mouth with 10 ml of the solution once daily after thoroughly brushing teeth. Rinse for 1 minute then spit out.

Children:
0.25 - 1 mg / day depending up on the age of the patient, dose is adjusted.
6 months - 3 years: 0.25 mg / day
3 years - 6 years: 0.5 mg / day
6 - 16 years: 1 mg / day
Schedule of Sodium fluoride Mouth Wash
N/A
Storage Requirements for Sodium fluoride Mouth Wash
Store at 15 - 30 degree C in a tightly closed light resistant container. Keep out of the reach of children.
Effects of Missed Dosage of Sodium fluoride Mouth Wash
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Sodium fluoride Mouth Wash
Give supportive measures and symptomatic treatment.

Home Delivery for Sodium fluoride Mouth Wash in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sodium fluoride mouth wash and other medicines and health products. Home delivery services for sodium fluoride mouth wash may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sodium fluoride mouth wash only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sodium fluoride mouth wash before they complete the sale. You can get this information while placing the order for sodium fluoride mouth wash with the pharmacy.

Sodium fluoride Mouth Wash is a generic medicine name and there are several brands available for it. Some of the brands for sodium fluoride mouth wash might be better known than sodium fluoride mouth wash itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sodium fluoride mouth wash in stock, you can ask for one of the branded alternatives for sodium fluoride mouth wash.