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- Pharmacology For Choline salicylate + Benzalkonium chloride
Choline salicylate + Benzalkonium chloride Pharmacology
Choline salicylate + Benzalkonium chlorideAbout Choline salicylate + Benzalkonium chlorideN/AMechanism of Action of Choline salicylate + Benzalkonium chlorideN/APharmacokinets of Choline salicylate + Benzalkonium chlorideN/AOnset of Action for Choline salicylate + Benzalkonium chlorideN/ADuration of Action for Choline salicylate + Benzalkonium chlorideN/AHalf Life of Choline salicylate + Benzalkonium chlorideN/ASide Effects of Choline salicylate + Benzalkonium chlorideN/AContra-indications of Choline salicylate + Benzalkonium chlorideN/ASpecial Precautions while taking Choline salicylate + Benzalkonium chlorideN/APregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicated; since Choline salicylate is contraindicated in breast feeding, the combination generic cannot be used in breast feeding motherChildren Related InformationN/AIndications for Choline salicylate + Benzalkonium chloride1.Mouth ulcers
Interactions for Choline salicylate + Benzalkonium chlorideN/ATypical Dosage for Choline salicylate + Benzalkonium chloridePut a drop on the tip of the finger and rub gently on to the affected areas, it may be repeated every 3-4 hours as requiredSchedule of Choline salicylate + Benzalkonium chlorideN/AStorage Requirements for Choline salicylate + Benzalkonium chlorideN/AEffects of Missed Dosage of Choline salicylate + Benzalkonium chlorideN/AEffects of Overdose of Choline salicylate + Benzalkonium chlorideN/A
Choline salicylateAbout Choline salicylateN/AMechanism of Action of Choline salicylateCholine salicylate has analgesic and anti-inflammatory action.
Peripheral action: It acts by inhibition of Prostaglandin (PGs) synthesis by blocking the activity of the precursor enzyme cyclo-oxygenase.
Anti-inflammatory action: It acts by inhibiting Prostaglandin (PGs) synthesis and their release at the site of injury. Prostaglandins cause tenderness and amplify the action of other algesics. Choline salicylate inhibits cyclo-oxygenase enzyme and antagonizes prostaglandin actions. It also inhibits other inflammatory mediators.
Pharmacokinets of Choline salicylateN/AOnset of Action for Choline salicylateN/ADuration of Action for Choline salicylateN/AHalf Life of Choline salicylateN/ASide Effects of Choline salicylate1.Salicylism
Contra-indications of Choline salicylate1.Hypersensitivity to Choline salicylate
2. Influenza in childrenSpecial Precautions while taking Choline salicylate1.Renal failure
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for Choline salicylate1.Pain
6.Juvenile rheumatoid arthritis
Interactions for Choline salicylateN/ATypical Dosage for Choline salicylateOral
Adults: 3g / day in single or in 2 divided doses.
Topical preparation: Apply the medicament to the affected area
Children: 1 - 2.25 g/ day in 2 divided doses
Below 3 years: Contraindicated
Schedule of Choline salicylateHStorage Requirements for Choline salicylateStore it at 15 -25 degree C in a tightly closed container .Protect away from heat and light. Keep out of the reach of children.Effects of Missed Dosage of Choline salicylateTake the missed dose as soon as noticed and if it is the time to take the next dose then skip the missed dose and continue the regular schedule. Do not double the dose.Effects of Overdose of Choline salicylateGive supportive measures and treatment.
Benzalkonium ChlorideAbout Benzalkonium ChlorideA nitrogenous cationic surfactant, Quaternary ammonium compound, Antiseptic,Disinfectant, A vaginal contraceptive spermicidal agent.Mechanism of Action of Benzalkonium ChlorideThe mechanism of bactericidal/microbicidal action is due to disruption of intermolecular interactions. This cause dissociation of cellular membrane bilayers, which compromises cellular permeability controls and induces leakage of cellular contents. Other biomolecular complexes within the bacterial cell can also undergo dissociation. It also inactivates the enzyme produced by different microorganisms. It also has spermicidal action. They work by damaging and killing sperm in the vagina. Therefore, the sperm are not able to travel from the vagina into the uterus and fallopian tubes, where fertilization usually takes place.Pharmacokinets of Benzalkonium ChlorideN/AOnset of Action for Benzalkonium ChlorideN/ADuration of Action for Benzalkonium ChlorideN/AHalf Life of Benzalkonium ChlorideN/ASide Effects of Benzalkonium Chloride1. Chills
6. Muscle aches
7. Sunburn-like skin rash
8. Cloudy or bloody urine
9. Increased frequency of urination
10. Pain in the bladder or lower abdomen
11. Pain on urination; thick
12. White or curd-like vaginal discharge-with use of cervical caps or diaphragms
13. Vaginal dryness
Contra-indications of Benzalkonium Chloride1. Hypersensitivity to the drug
2. Allergies, irritations, or infections of the genitals
3. Recent abortion
4. Sores on the genitals (sex organs)
5. Irritation of the vagina
Special Precautions while taking Benzalkonium ChlorideDiscontinue use if you have abnormal discharge or vaginal burning or itching.Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Benzalkonium Chloride1. Antisepsis of skin, mucous membranes, and wounds.
2. Preoperative preparation of the skin, surgeons` hand and arm soaks
3. Treatment of wounds
4. Preservation of ophthalmic solutions
5. Irrigations of the eye, body cavities, bladder, urethra
6. Vaginal douching.
Interactions for Benzalkonium ChlorideN/ATypical Dosage for Benzalkonium ChlorideVaginal suppositories dosage form (preventing pregnancy):
Adults and teenagers-
For use alone: One suppository inserted into the vagina at least ten minutes but not longer than four hours before each time you have sexual intercourse.
With a diaphragm: After the diaphragm with spermicide has been placed into the vagina, insert one suppository at least ten minutes, but not longer than four hours, before each time you have sexual intercourse. Also, insert another suppository before sexual intercourse if six hours have passed since you inserted the diaphragm
Schedule of Benzalkonium ChlorideN/AStorage Requirements for Benzalkonium ChlorideStore at controlled room temperature, away from light and excessive heat. Keep out of reach of children.Effects of Missed Dosage of Benzalkonium ChlorideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Benzalkonium ChlorideN/A
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