Lactitol Pharmacology

Lactitol

About Lactitol
It is an Osmotic laxative.
Mechanism of Action of Lactitol
In the colon it is broken down to short chain organic acids and acidify,this results in an increase in osmotic pressure in the colon, thereby causing an increase in the stool water content and stool volume which explains the laxative effect.
Pharmacokinets of Lactitol
Absorption: Lactitol is not significantly absorbed in the small intestine; only 0.5% to 2% of a dose is
partially absorbed as unchanged lactitol
Metabolism: Absorbed volatile fatty acids are either metabolized in the colon
Excretion: 6.5% excreted in the feces. Small amounts of unchanged lactitol appear in the urine (2% or less of a dose).
Onset of Action for Lactitol
24 to 48 hrs
Duration of Action for Lactitol
N/A
Half Life of Lactitol
N/A
Side Effects of Lactitol
1. Rectal irritation
2. Dangerous potassium loss.
3. Headache
4. Confusion
5. Rash
Contra-indications of Lactitol
1.Appendicitis
2.Abdominal pain or bleeding
3.Hypersensitivity to the drug
4.Galactosemia.
Special Precautions while taking Lactitol
1. Gastro intestinal problem
2. Cardio vascular problem
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Lactitol
1.Constipation relief
2.Chronic cholecystitis
3.Prevention of hepatic encephalopathy.
Interactions for Lactitol
1. Antacids tablet coating may dissolve too rapidly, irritating stomach or bowel.
2. Antihypertensives may cause dangerous low potassium level.
3. Diureticsm may cause dangerous low potassium level.
Typical Dosage for Lactitol
Adults: 15 to 30 mL (10 to 20 g lactulose) daily; may increase to 60 mL/day.
Older Children and Adolescents: 40 to 90 mL/day in divided doses to produce 2 to 3 soft stools/day
Infants: 2.5 to 10 mL/day in divided doses to produce 2 to 3 soft stools/day
Schedule of Lactitol
H
Storage Requirements for Lactitol
Store at room temperature (below 86?F). Do not freeze.
Effects of Missed Dosage of Lactitol
N/A
Effects of Overdose of Lactitol
N/A

Home Delivery for Lactitol in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including lactitol.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for lactitol and other medicines and health products. Home delivery services for lactitol may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take lactitol only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for lactitol before they complete the sale. You can get this information while placing the order for lactitol with the pharmacy.

Lactitol is a generic medicine name and there are several brands available for it. Some of the brands for lactitol might be better known than lactitol itself. If the pharmacy that's willing to deliver medicines to your home doesn't have lactitol in stock, you can ask for one of the branded alternatives for lactitol.