Oseltamivir Pharmacology

Oseltamivir

About Oseltamivir
Antiviral,Neuraminidase inhibitor
Mechanism of Action of Oseltamivir
Oseltamivir is an ethyl ester prodrug requiring ester hydrolysis for conversion to active form oseltamivir carboxylate. Oseltamivir is a neuraminidase inhibitor, serving as a competitive inhibitor towards sialic acid, found on the surface proteins of normal host cells. By blocking the activity of the viral neuraminidase (NA) enzyme, oseltamivir prevents new viral particles from being released by infected cells.
Pharmacokinets of Oseltamivir
Absorption: Absorbed after oral administration
Distribution: Widely distributed
Metabolism: Metabolised in the liver
Excretion: Excreted through urine
Onset of Action for Oseltamivir
N/A
Duration of Action for Oseltamivir
N/A
Half Life of Oseltamivir
6 to 10 hrs
Side Effects of Oseltamivir
1.Nausea
2.Vomiting
3.Diarrhea
4.Bronchitis
5.Conjunctivitis
6.Dermatitis
7.Ear disorder
8.Sinusitis
Contra-indications of Oseltamivir
Hypersensitivity
Special Precautions while taking Oseltamivir
1.Renal impairment
2.Hepatic impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Oseltamivir
Treatment and prevention of infections due to influenza A and B viruses.
Interactions for Oseltamivir
Oseltamivir+Probenecid: Oseltamivir has its toxicity increased by probenecid.
Typical Dosage for Oseltamivir
Adult and Adolescents: 75 mg twice daily for 5 days
Children: 6 to 12 months: 3 mg/kg body weight twice daily for 5 days
Schedule of Oseltamivir
H
Storage Requirements for Oseltamivir
Store at 15 to 30 degree C in a tightly closed container.Keep out of the reach of children
Effects of Missed Dosage of Oseltamivir
N/A
Effects of Overdose of Oseltamivir
N/A

Home Delivery for Oseltamivir in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including oseltamivir.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for oseltamivir and other medicines and health products. Home delivery services for oseltamivir may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take oseltamivir only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for oseltamivir before they complete the sale. You can get this information while placing the order for oseltamivir with the pharmacy.

Oseltamivir is a generic medicine name and there are several brands available for it. Some of the brands for oseltamivir might be better known than oseltamivir itself. If the pharmacy that's willing to deliver medicines to your home doesn't have oseltamivir in stock, you can ask for one of the branded alternatives for oseltamivir.