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- Pharmacology For Dextran + Hydroxypropyl Methyl Cellulose
Dextran + Hydroxypropyl Methyl Cellulose Pharmacology
Dextran + Hydroxypropyl Methyl Cellulose
About Dextran + Hydroxypropyl Methyl CelluloseN/AMechanism of Action of Dextran + Hydroxypropyl Methyl CelluloseN/APharmacokinets of Dextran + Hydroxypropyl Methyl CelluloseN/AOnset of Action for Dextran + Hydroxypropyl Methyl CelluloseN/ADuration of Action for Dextran + Hydroxypropyl Methyl CelluloseN/AHalf Life of Dextran + Hydroxypropyl Methyl CelluloseN/ASide Effects of Dextran + Hydroxypropyl Methyl CelluloseN/AContra-indications of Dextran + Hydroxypropyl Methyl CelluloseN/ASpecial Precautions while taking Dextran + Hydroxypropyl Methyl CelluloseN/APregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationMay be usedChildren Related InformationN/AIndications for Dextran + Hydroxypropyl Methyl CelluloseDry eyesInteractions for Dextran + Hydroxypropyl Methyl CelluloseN/ATypical Dosage for Dextran + Hydroxypropyl Methyl CelluloseInstil 1-2 drops into the affected eyeSchedule of Dextran + Hydroxypropyl Methyl CelluloseN/AStorage Requirements for Dextran + Hydroxypropyl Methyl CelluloseStore in a well closed container. Keep out of the reach of childrenEffects of Missed Dosage of Dextran + Hydroxypropyl Methyl CelluloseN/AEffects of Overdose of Dextran + Hydroxypropyl Methyl CelluloseN/ADextran
About DextranA group of long-chain Polysaccharides composed of glucose,Intravenous fluids, Plasma expanders (((substitutes for whole blood))) in severe shock.Mechanism of Action of DextranDextran is a plasma volume expander which reduces blood viscosity. It forms a coating on RBC and maintains their electronegative charge and prevents RBC sludging that occurs in shock. It improves microcirculation. They are both osmotically active, and too large to pass through the uninjured vessel wall. They possess antiplatelet and anti-fibrin activities. They bind to platelets, RBCs, and the lining of the vessel wall decreasing their ability to stick together and forming clots.Pharmacokinets of DextranAbsorption: Administered intravenously, Metabolism: Partially oxidized in the body, Excretion: Excreted through urine.Onset of Action for DextranN/ADuration of Action for DextranN/AHalf Life of DextranN/ASide Effects of Dextran1.Urticaria
2.Itching
3.Fever
4.Joint pain
5.Stomach pain
6.Nausea
7.Vomiting
8.Bronchospasm
9.Fall in BP
10.Pain and burning sensation at the injection site
11.Allergic reactions
12.Rashes
13.Stuffy nose
14.Tightness in the chest
15.Wheezing
16.Unusual swelling
17.Difficulty in passing urine
Contra-indications of Dextran1.Hypersensitivity to Dextran
2.Hypofibrinogenemia
3.Thrombocytopenia
4.Haemorrhage.
Special Precautions while taking DextranUse with caution in following conditions:
1.Closely monitor patient condition and vital parameters during Dextran administration 2.Bleeding disorders
3.Dehydration
4.Cardiac diseases
5.Renal impairment
6.Pulmonary oedema
7.Low sodium diet.
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Dextran1.Shock
2.Foetal distress syndrome
3.Cerebrovascular accident
4.Prevention of peritoneal adhesions.
Interactions for DextranN/ATypical Dosage for DextranI.V.: Dosage individualized based on patient`s requirements. Total dose should not exceed 20ml/kg/24 hours.
After micro vascular transplantation:
Adults: 25cc/hour postoperatively for five days.
Children: 8-10 cc/kg/24hrs
Schedule of DextranCStorage Requirements for DextranStore at a temperature range of 2 to 80C. Keep out of reach of children.Effects of Missed Dosage of DextranN/AEffects of Overdose of DextranProvide symptomatic treatment and supportive measures.Hydroxypropyl Methyl Cellulose
About Hydroxypropyl Methyl CelluloseA semisynthetic, inert, viscoelastic polymer, Ophthalmic lubricant ,Artificial tears.Mechanism of Action of Hydroxypropyl Methyl CelluloseHydroxy Propyl methylcellulose belongs to the group of medicines known as artificial tears. Artificial tears are used to treat the keratoconjunctivitis sicca (dryness) and irritation in the eye. They are also used to moisten contact lenses and in eye examinations. These moisten lenses and remove particulate matter that causes irritation.
The surface active properties of the Hydroxy Propyl methyl cellulose (vehicles) found in artificial tears solutions act to stabilize the tear film and increase tear viscosity to prevent tear evaporation and retard tear drainage. The vehicles found in bland lubricant artificial tear ointments also enhance the tear film and additionally have a prolonged duration of action in the eye versus artificial tear solutions.
It is used to relieve dryness and irritation caused by reduced tear flow. It helps prevent damage to the eye in certain eye diseases. Hydroxy Propyl methylcellulose may also be used to moisten hard contact lenses and artificial eyes. In addition, it may be used in certain eye examinations
Pharmacokinets of Hydroxypropyl Methyl CelluloseN/AOnset of Action for Hydroxypropyl Methyl CelluloseN/ADuration of Action for Hydroxypropyl Methyl CelluloseN/AHalf Life of Hydroxypropyl Methyl CelluloseN/ASide Effects of Hydroxypropyl Methyl Cellulose1.Eye irritation
2.Stickiness of eyelashes
3.Blurred vision
4.Redness of eyes
Contra-indications of Hydroxypropyl Methyl CelluloseN/ASpecial Precautions while taking Hydroxypropyl Methyl Cellulose1.Eye pain
2.Changes in vision
3.Continued redness or irritation of the eye
4.Excessive tearing or if symptoms continue for more than 3 days or become worse consult doctor.
Pregnancy Related InformationMay be usedOld Age Related InformationMay be usedBreast Feeding Related InformationMay be usedChildren Related InformationMay be used
NEONATES: may be used
Indications for Hydroxypropyl Methyl CelluloseAid in anterior surgical preparations:
1.Cataract surgery
2.Intraocular lens implantation
3.Diagnostic aid in Gonioscopy
4.In keratoplasty
5.Diagnostic aid in contact lens procedures
6.Artificial tear
7.Lubricant in ophthalmic preparations
8.Protectant in ophthalmic preparations
9.Moistening of daily wear soft lenses
Interactions for Hydroxypropyl Methyl CelluloseN/ATypical Dosage for Hydroxypropyl Methyl CelluloseDOSAGE: Hydroxy Propyl methylcellulose (HPMC) 0.3% is used
For dry eyes:
Adults and children-Instill 1 drop 3 -4 times a day. Dose is depending on the patient`s response
Schedule of Hydroxypropyl Methyl CelluloseN/AStorage Requirements for Hydroxypropyl Methyl CelluloseStore at room temperature. Keep in a tightly closed container. Keep out of the reach of childrenEffects of Missed Dosage of Hydroxypropyl Methyl CelluloseInstill the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Hydroxypropyl Methyl CelluloseGive supportive measures and symptomatic treatment. The exposed eye should be irrigated with copious amounts of water for at least 15 minutes.Home Delivery for Dextran + Hydroxypropyl Methyl Cellulose in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including dextran + hydroxypropyl methyl cellulose.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for dextran + hydroxypropyl methyl cellulose and other medicines and health products. Home delivery services for dextran + hydroxypropyl methyl cellulose may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take dextran + hydroxypropyl methyl cellulose only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for dextran + hydroxypropyl methyl cellulose before they complete the sale. You can get this information while placing the order for dextran + hydroxypropyl methyl cellulose with the pharmacy.
Dextran + Hydroxypropyl Methyl Cellulose is a generic medicine name and there are several brands available for it. Some of the brands for dextran + hydroxypropyl methyl cellulose might be better known than dextran + hydroxypropyl methyl cellulose itself. If the pharmacy that's willing to deliver medicines to your home doesn't have dextran + hydroxypropyl methyl cellulose in stock, you can ask for one of the branded alternatives for dextran + hydroxypropyl methyl cellulose.
