Rabies Immunoglobulin Pharmacology

Rabies Immunoglobulin

About Rabies Immunoglobulin
Passive immunizing agent,immunoglobulin, Rabies prophylaxis.
Mechanism of Action of Rabies Immunoglobulin
Rabies immunoglobulin (specific neutralizing antibodies against rabies virus) confers passive immunity against rabies.
Pharmacokinets of Rabies Immunoglobulin
Onset of Action for Rabies Immunoglobulin
Duration of Action for Rabies Immunoglobulin
Half Life of Rabies Immunoglobulin
Side Effects of Rabies Immunoglobulin
1. Pain and tenderness occur at the injection site
2. Headache
3. Fever
4. Chills
5. Flushing
6. Light headedness
7. Backache
8. Nausea
Contra-indications of Rabies Immunoglobulin
1. Hyper sensitivity to the drug
2. IgA deficiency or history of it
3. Anaphylactic reactions to plasma products should be considered

Special Precautions while taking Rabies Immunoglobulin
1. Repeated doses of the rabies immunoglobulin should not be administered once rabies vaccine treatment has been started, because this could prevent full development of the active immunity expected from the vaccine.
2. Use with caution in patients receiving human blood or plasma-derived medicinal products.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Rabies Immunoglobulin
1. Rabies infection of all category III exposures (single or multiple transdermal bites or scratches or contamination of mucous membrane with saliva), irrespective of the interval between exposure and beginning of treatment.
Interactions for Rabies Immunoglobulin
Typical Dosage for Rabies Immunoglobulin
Adults and children-
Post exposure-
Children and adults: 20 IU per kilogram body mass for Human rabies immunoglobulin (HRIG) or 40 IU/kg of body weight of Equine rabies immunoglobulin (ERIG) infiltrated in and around the wound as much as anatomically feasible but at a different anatomical site, as the vaccine. Administer the remainder of the dose by deep intramuscular injection at a site separate from that used for the vaccine. Ensure that the wound has been adequately infiltrated with immunoglobulin locally before suturing, if suturing is necessary.
Schedule of Rabies Immunoglobulin
Storage Requirements for Rabies Immunoglobulin
Store between 2?C and 8?C.Do not freeze. Protect from light. Keep out of reach of children.
Effects of Missed Dosage of Rabies Immunoglobulin
The doctor should be informed immediately if a dose is missed.
Effects of Overdose of Rabies Immunoglobulin
Give symptomatic and supportive treatment.

Home Delivery for Rabies Immunoglobulin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including rabies immunoglobulin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for rabies immunoglobulin and other medicines and health products. Home delivery services for rabies immunoglobulin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take rabies immunoglobulin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for rabies immunoglobulin before they complete the sale. You can get this information while placing the order for rabies immunoglobulin with the pharmacy.

Rabies Immunoglobulin is a generic medicine name and there are several brands available for it. Some of the brands for rabies immunoglobulin might be better known than rabies immunoglobulin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have rabies immunoglobulin in stock, you can ask for one of the branded alternatives for rabies immunoglobulin.