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- Pharmacology For Camylofin dihydrochloride + Diclofenac Sodium
Camylofin dihydrochloride + Diclofenac Sodium Pharmacology
Camylofin dihydrochloride + Diclofenac SodiumAbout Camylofin dihydrochloride + Diclofenac SodiumN/AMechanism of Action of Camylofin dihydrochloride + Diclofenac SodiumN/APharmacokinets of Camylofin dihydrochloride + Diclofenac SodiumN/AOnset of Action for Camylofin dihydrochloride + Diclofenac SodiumN/ADuration of Action for Camylofin dihydrochloride + Diclofenac SodiumN/AHalf Life of Camylofin dihydrochloride + Diclofenac SodiumN/ASide Effects of Camylofin dihydrochloride + Diclofenac SodiumN/AContra-indications of Camylofin dihydrochloride + Diclofenac SodiumN/ASpecial Precautions while taking Camylofin dihydrochloride + Diclofenac SodiumN/APregnancy Related InformationContraindicated;since Diclofenac sodium is contraindicated in pregnancyOld Age Related InformationN/ABreast Feeding Related InformationLactation: Contraindicated;since Diclofenac sodium is contraindicated in breast feeding.Children Related InformationN/AIndications for Camylofin dihydrochloride + Diclofenac Sodium1.Renal colic
Interactions for Camylofin dihydrochloride + Diclofenac SodiumN/ATypical Dosage for Camylofin dihydrochloride + Diclofenac SodiumAdults:1 tablet to be taken 3 times daily
Child:1 tablet to be taken 2 times daily
Schedule of Camylofin dihydrochloride + Diclofenac SodiumN/AStorage Requirements for Camylofin dihydrochloride + Diclofenac SodiumN/AEffects of Missed Dosage of Camylofin dihydrochloride + Diclofenac SodiumN/AEffects of Overdose of Camylofin dihydrochloride + Diclofenac SodiumN/A
Camylofin dihydrochlorideAbout Camylofin dihydrochlorideSynthetic anticholinergic, direct smooth muscle relaxant.Mechanism of Action of Camylofin dihydrochlorideCamylofin dihydrochloride is a potent antispasmodic and is useful in active phase of labor. It accelerates the rate of cervical dilatation and shortens the duration of active phase of first stage of labor significantly without any undesirable effects on the fetus. It has no effect on the second and third stage of labor and no effect on uterine activity.Pharmacokinets of Camylofin dihydrochlorideN/AOnset of Action for Camylofin dihydrochlorideN/ADuration of Action for Camylofin dihydrochlorideN/AHalf Life of Camylofin dihydrochlorideN/ASide Effects of Camylofin dihydrochloride1. Dryness of mouth
5. Transient tachycardia
Contra-indications of Camylofin dihydrochloride1.Glucoma
2.Urinary retention (adynamic bladder)
Special Precautions while taking Camylofin dihydrochloride1.Urinary retention
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Camylofin dihydrochloride1.Used as antispasmodic in biliary colic, renal and ureteric colic, dysmenorrhoea, peptic ulcer and chronic enterocolitis.Interactions for Camylofin dihydrochlorideN/ATypical Dosage for Camylofin dihydrochlorideAdult:
As antispasmodics: (IM or IV ) 0.285 to 0.857 mg / kg to be taken every 8 hours
Schedule of Camylofin dihydrochlorideN/AStorage Requirements for Camylofin dihydrochlorideN/AEffects of Missed Dosage of Camylofin dihydrochlorideThe doctor should be informed immediately if a dose is missedEffects of Overdose of Camylofin dihydrochlorideGive supportive measures and symptomatic treatment
Diclofenac SodiumAbout Diclofenac SodiumN/AMechanism of Action of Diclofenac SodiumDiclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (PGs). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake. .Pharmacokinets of Diclofenac SodiumAbsorption: Diclofenac sodium is rapidly absorbed after oral administration. It undergoes first pass metabolism and its bioavailability is 50 % only. Distribution: It is distributed in highly protein bound form. Metabolism: Diclofenac sodium is metabolised in the liver. Excretion: Drug and metabolites are primarily excreted in urine and some amount in the bile.Onset of Action for Diclofenac Sodium1- 4.5 hoursDuration of Action for Diclofenac SodiumHoursHalf Life of Diclofenac Sodium2 hoursSide Effects of Diclofenac Sodium1.Nausea
9.Ulceration of the stomach or intestine
Contra-indications of Diclofenac Sodium1.Hypersensitivity to Indomethacin and other Non steroidal anti inflammatory drugs(NSAID)
Special Precautions while taking Diclofenac Sodium1.Hepatic impairment
4.Blood clotting disorders
8.Cautioned against driving, operating or activities requiring concentration
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with caution
CHILDREN below 14: contraindicatedIndications for Diclofenac Sodium1.Ankylosing spondylitis
3.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints
5.For the relief of pain and inflammation in dental minor surgery and orthopedic
7.Juvenile chronic arthritis
Interactions for Diclofenac SodiumLithium & Digoxin : Blood levels of lithium and digoxin increased leading to enhanced efficacy and posible toxicity.
Diuretics : Inhibits diuretics but efficacy of potassium sparing diuretics enhanced.
Methotrexate : Toxicity enhanced.
Salicylates : Efficacy of salicylates reduced.
Cyclosporine : Increases nephrotoxicity of both agents.
Hydantoins : Increases serum levels resulting in toxicity.
Typical Dosage for Diclofenac SodiumAdult: 100 - 150 mg / day in 2 - 3 divided doses.
For the relief of pain, Migraine, Dysmenorrhoea: 150 mg / day in 3 divided doses.
Osteoarthritis: 50 mg 2 - 3 times daily
Rheumatoid arthritis: 150 - 200 mg / day in 3 - 4 divided doses.
Ankylosing spondylitis: 25 mg 4 times daily give an extra dose of 25 mg at bed time if necessary.
Children Juvenile rheumatoid arthritis: 0.5 - 2 mg / kg body weight / day in divided doses.
Maximum dose: 3 mg / kg body weight / day in divided doses
Schedule of Diclofenac SodiumHStorage Requirements for Diclofenac SodiumStore Diclofenac sodium at room temperature in a tightly closed light resistant container.Effects of Missed Dosage of Diclofenac SodiumTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Diclofenac SodiumGive supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal.
Home Delivery for Camylofin dihydrochloride + Diclofenac Sodium in Your City
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Camylofin dihydrochloride + Diclofenac Sodium is a generic medicine name and there are several brands available for it. Some of the brands for camylofin dihydrochloride + diclofenac sodium might be better known than camylofin dihydrochloride + diclofenac sodium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have camylofin dihydrochloride + diclofenac sodium in stock, you can ask for one of the branded alternatives for camylofin dihydrochloride + diclofenac sodium.