Camylofin dihydrochloride + Diclofenac Sodium Pharmacology

Camylofin dihydrochloride + Diclofenac Sodium

About Camylofin dihydrochloride + Diclofenac Sodium
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Mechanism of Action of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Pharmacokinets of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Onset of Action for Camylofin dihydrochloride + Diclofenac Sodium
N/A
Duration of Action for Camylofin dihydrochloride + Diclofenac Sodium
N/A
Half Life of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Side Effects of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Contra-indications of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Special Precautions while taking Camylofin dihydrochloride + Diclofenac Sodium
N/A
Pregnancy Related Information
Contraindicated;since Diclofenac sodium is contraindicated in pregnancy
Old Age Related Information
N/A
Breast Feeding Related Information
Lactation: Contraindicated;since Diclofenac sodium is contraindicated in breast feeding.
Children Related Information
N/A
Indications for Camylofin dihydrochloride + Diclofenac Sodium
1.Renal colic
2.Biliary colic
3.Intestinal colic
4.Primary dysmenorrhoea
Interactions for Camylofin dihydrochloride + Diclofenac Sodium
N/A
Typical Dosage for Camylofin dihydrochloride + Diclofenac Sodium
Adults:1 tablet to be taken 3 times daily
Child:1 tablet to be taken 2 times daily
Schedule of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Storage Requirements for Camylofin dihydrochloride + Diclofenac Sodium
N/A
Effects of Missed Dosage of Camylofin dihydrochloride + Diclofenac Sodium
N/A
Effects of Overdose of Camylofin dihydrochloride + Diclofenac Sodium
N/A

Camylofin dihydrochloride

About Camylofin dihydrochloride
Synthetic anticholinergic, direct smooth muscle relaxant.
Mechanism of Action of Camylofin dihydrochloride
Camylofin dihydrochloride is a potent antispasmodic and is useful in active phase of labor. It accelerates the rate of cervical dilatation and shortens the duration of active phase of first stage of labor significantly without any undesirable effects on the fetus. It has no effect on the second and third stage of labor and no effect on uterine activity.
Pharmacokinets of Camylofin dihydrochloride
N/A
Onset of Action for Camylofin dihydrochloride
N/A
Duration of Action for Camylofin dihydrochloride
N/A
Half Life of Camylofin dihydrochloride
N/A
Side Effects of Camylofin dihydrochloride
1. Dryness of mouth
2. Nausea
3. Vomiting
4. Drowsiness
5. Transient tachycardia
Contra-indications of Camylofin dihydrochloride
1.Glucoma
2.Urinary retention (adynamic bladder)
3.Mega colon
4.Gastrointestinal haemorrhage
5.Tachyarrythmia.
Special Precautions while taking Camylofin dihydrochloride
1.Urinary retention
2.Prostatic enlargement
3.Tachycardia
4.Cardiac insufficiency
5.Paralytic ileus
6.Ulcerative colitis
7.Pylonic stenosis
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Camylofin dihydrochloride
1.Used as antispasmodic in biliary colic, renal and ureteric colic, dysmenorrhoea, peptic ulcer and chronic enterocolitis.
Interactions for Camylofin dihydrochloride
N/A
Typical Dosage for Camylofin dihydrochloride
Adult:
As antispasmodics: (IM or IV ) 0.285 to 0.857 mg / kg to be taken every 8 hours
Schedule of Camylofin dihydrochloride
N/A
Storage Requirements for Camylofin dihydrochloride
N/A
Effects of Missed Dosage of Camylofin dihydrochloride
The doctor should be informed immediately if a dose is missed
Effects of Overdose of Camylofin dihydrochloride
Give supportive measures and symptomatic treatment

Diclofenac Sodium

About Diclofenac Sodium
N/A
Mechanism of Action of Diclofenac Sodium
Diclofenac possess analgesic, anti-inflammatory and antipyretic action. It inhibits the enzyme cyclo-oxygenase and there by inhibits the synthesis of Prostaglandins (PGs). It is more potent against cyclo-oxygenase-2 enzyme as compared to other NSAIDs like Indomethacin, Naproxen etc. It reduces intracellular concentrations of free arachidonic acid in leukocyte by altering its release or uptake. .
Pharmacokinets of Diclofenac Sodium
Absorption: Diclofenac sodium is rapidly absorbed after oral administration. It undergoes first pass metabolism and its bioavailability is 50 % only. Distribution: It is distributed in highly protein bound form. Metabolism: Diclofenac sodium is metabolised in the liver. Excretion: Drug and metabolites are primarily excreted in urine and some amount in the bile.
Onset of Action for Diclofenac Sodium
1- 4.5 hours
Duration of Action for Diclofenac Sodium
Hours
Half Life of Diclofenac Sodium
2 hours
Side Effects of Diclofenac Sodium
1.Nausea
2.Vomiting
3.Anorexia
4.Diarrhoea
5.Gastrointestinal bleeding
6.Abdominal distress
7.Constipation
8.Flatulence
9.Ulceration of the stomach or intestine
10.Dyspepsia
11.Headache
12.Dizziness
13. Rash
Contra-indications of Diclofenac Sodium
1.Hypersensitivity to Indomethacin and other Non steroidal anti inflammatory drugs(NSAID)
2.Peptic ulcer
3.Asthma
Special Precautions while taking Diclofenac Sodium
1.Hepatic impairment
2.Renal impairment
3.Hypertension
4.Blood clotting disorders
5.Gastrointestinal diseases
6.Proctitis
7.Asthma
8.Cautioned against driving, operating or activities requiring concentration
9.Avoid alcohol
10.Heart failure
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
CHILDREN below 14: contraindicated
Indications for Diclofenac Sodium
1.Ankylosing spondylitis
2.Acute gout
3.Joint disorders e.g. inflammatory disease in joints, crystal deposition in the joints
4.Osteoarthritis
5.For the relief of pain and inflammation in dental minor surgery and orthopedic
6.Dysmenorrhoea
7.Juvenile chronic arthritis
8.Migraine
Interactions for Diclofenac Sodium
Lithium & Digoxin : Blood levels of lithium and digoxin increased leading to enhanced efficacy and posible toxicity.
Diuretics : Inhibits diuretics but efficacy of potassium sparing diuretics enhanced.
Methotrexate : Toxicity enhanced.
Salicylates : Efficacy of salicylates reduced.
Cyclosporine : Increases nephrotoxicity of both agents.
Hydantoins : Increases serum levels resulting in toxicity.
Typical Dosage for Diclofenac Sodium
Adult: 100 - 150 mg / day in 2 - 3 divided doses.
For the relief of pain, Migraine, Dysmenorrhoea: 150 mg / day in 3 divided doses.
Osteoarthritis: 50 mg 2 - 3 times daily
Rheumatoid arthritis: 150 - 200 mg / day in 3 - 4 divided doses.
Ankylosing spondylitis: 25 mg 4 times daily give an extra dose of 25 mg at bed time if necessary.
Children Juvenile rheumatoid arthritis: 0.5 - 2 mg / kg body weight / day in divided doses.
Maximum dose: 3 mg / kg body weight / day in divided doses
Schedule of Diclofenac Sodium
H
Storage Requirements for Diclofenac Sodium
Store Diclofenac sodium at room temperature in a tightly closed light resistant container.
Effects of Missed Dosage of Diclofenac Sodium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Diclofenac Sodium
Give supportive measures and symptomatic treatment. Drug can be removed from the body by gastric lavage or by inducing emesis. Absorption of the drug can be reduced by administration of activated charcoal.

Home Delivery for Camylofin dihydrochloride + Diclofenac Sodium in Your City

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Camylofin dihydrochloride + Diclofenac Sodium is a generic medicine name and there are several brands available for it. Some of the brands for camylofin dihydrochloride + diclofenac sodium might be better known than camylofin dihydrochloride + diclofenac sodium itself. If the pharmacy that's willing to deliver medicines to your home doesn't have camylofin dihydrochloride + diclofenac sodium in stock, you can ask for one of the branded alternatives for camylofin dihydrochloride + diclofenac sodium.