Sulpiride Pharmacology

Sulpiride

About Sulpiride
Synthetic Origin, D2 Antagonist.
Mechanism of Action of Sulpiride
Sulpride block both dopamine D1 and D2 receptors, Sulpiride is more selective and acts primarily as a dopamine D2 antagonist. Sulpiride appears to lack effects on norepinephrine, acetylcholine, serotonin, histamine, or gamma-aminobutyric acid (GABA) receptors.
Pharmacokinets of Sulpiride
Absorption: Absorbed after oral administration
Excretion: Excreted through urine
Onset of Action for Sulpiride
N/A
Duration of Action for Sulpiride
N/A
Half Life of Sulpiride
7 hrs
Side Effects of Sulpiride
1.Postural hypotension
2.Hyperprolactinaemia
3.Weight gain
4.Sedation
5.Insomnia
Contra-indications of Sulpiride
1.CNS depression
2.Pheochromocytoma
3.Porphyria
Special Precautions while taking Sulpiride
1.Impaired renal function
2.Hepatic
3.Parkinson's disease
4.CV disease
5.Severe resp disease
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindication
Children Related Information
Use with caution
Indications for Sulpiride
Schizophrenia
Interactions for Sulpiride
1.Concurrent use with lithium increases the risk of extrapyramidal side effects 2.Concurrent use with antacids or sucralfate may affect sulpiride absorption
3.Efficacy may be reduced by dopamine agonists
4.Increased postural hypotension if used with other antihypertensive drugs
Typical Dosage for Sulpiride
200 to 400 mg daily. Max: 800 mg daily
Child: >14 yr: 3-5 mg/kg daily
Schedule of Sulpiride
N/A
Storage Requirements for Sulpiride
Store below 25 degree celcius in a well closed container. Keep out of the reach of children.

Effects of Missed Dosage of Sulpiride
N/A
Effects of Overdose of Sulpiride
N/A

Home Delivery for Sulpiride in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including sulpiride.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for sulpiride and other medicines and health products. Home delivery services for sulpiride may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take sulpiride only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for sulpiride before they complete the sale. You can get this information while placing the order for sulpiride with the pharmacy.

Sulpiride is a generic medicine name and there are several brands available for it. Some of the brands for sulpiride might be better known than sulpiride itself. If the pharmacy that's willing to deliver medicines to your home doesn't have sulpiride in stock, you can ask for one of the branded alternatives for sulpiride.