Quinapril Hydrochloride Pharmacology

Quinapril Hydrochloride

About Quinapril Hydrochloride
ACE Inhibitors, Antihypertensives
Mechanism of Action of Quinapril Hydrochloride
Quinapril is a competitive inhibitor of angiotensin-converting enzyme (ACE). It prevents conversion of angiotensin I to angiotensin II resulting in lower levels of angiotensin II which causes an increase in plasma renin activity and a reduction in aldosterone secretion.
Pharmacokinets of Quinapril Hydrochloride
Absorption: Absorbed after oral administration
Distribution: 97% bound to plasma proteins
Metabolism: Metabolised in the liver
Excretion: Excreted in the urine and faeces
Onset of Action for Quinapril Hydrochloride
I hr after oral administration
Duration of Action for Quinapril Hydrochloride
About 24 hrs
Half Life of Quinapril Hydrochloride
2 hrs
Side Effects of Quinapril Hydrochloride
4.Stomach upset
Contra-indications of Quinapril Hydrochloride
1.Aortic stenosis or outflow tract obstruction
2.Renovascular disease
3.Hypersensitivity to the component
Special Precautions while taking Quinapril Hydrochloride
1.Peripheral vascular diseases
2.Heart failure
3.Liver cirrhosis
Pregnancy Related Information
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Quinapril Hydrochloride
2.Heart failure
Interactions for Quinapril Hydrochloride
1.Additive hyperkalaemic effects with potassium-sparing diuretics, potassium supplements, other drugs that can cause hyperkalaemia
2.Increased risk of renal impairment and reduced antihypertensive effect when used with NSAIDs
3.Excessive hypotension with diuretics, other antihypertensives, alcohol
Typical Dosage for Quinapril Hydrochloride
Adult: Initially, 10 mg once daily. Maintenance: 20-40 mg daily as a single dose or in 2 divided doses.
Elderly: Initially, 2.5 mg daily
Heart failure
Adult: Initially, 2.5 mg daily. Maintenance: 10-20 mg daily as a single dose or in 2 divided doses. Max dose: 40 mg daily.
Schedule of Quinapril Hydrochloride
Storage Requirements for Quinapril Hydrochloride
Store below 30 degree celcius in a well closed container. Keep out of the reach of children.
Effects of Missed Dosage of Quinapril Hydrochloride
Effects of Overdose of Quinapril Hydrochloride

Home Delivery for Quinapril Hydrochloride in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including quinapril hydrochloride.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for quinapril hydrochloride and other medicines and health products. Home delivery services for quinapril hydrochloride may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take quinapril hydrochloride only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for quinapril hydrochloride before they complete the sale. You can get this information while placing the order for quinapril hydrochloride with the pharmacy.

Quinapril Hydrochloride is a generic medicine name and there are several brands available for it. Some of the brands for quinapril hydrochloride might be better known than quinapril hydrochloride itself. If the pharmacy that's willing to deliver medicines to your home doesn't have quinapril hydrochloride in stock, you can ask for one of the branded alternatives for quinapril hydrochloride.