Paliperidone Pharmacology
Paliperidone
Distribution: Protein binding: 74%.
Metabolism: Hepatic via CYP2D6 and 3A4.
Excretion:. Excreted in urine (80%) and faeces (11%).
2.Extrapyramidal disorder, including involuntary movements, tremors and muscle stiffness
3.Tardive diskinesia
4.Hyperprolactinemia
5.Tachycardia
6.Headache
7.Somnolence
8.Orthostatic hypotension
9.AV block
10.Bundle branch block
2.Avoid use in patients with Congenital long-QT syndrome or history of cardiac arrhythmia.
3.May cause Oesophageal dysmotility and aspiration; caution in patients at risk of Pneumonia.
4.Increased risk of tardive dyskinesia in the elderly, especially women.
5.Monitor glucose control in patients with or with risk factors for diabetes or other disorders of glucose regulation.
6.Monitor for mental status changes, fever, muscle rigidity and/or autonomic instability.
7.May cause Orthostatic hypotension, impaired core body temperature, significant wt gain and/or sedation.
8.Monitor for behaviour changes or suicidal ideation.
9.Patients with Breast cancer or other prolactin-dependent tumors, Renal impairment or at risk of seizures.
10.May mask toxicity of other drugs or conditions e.g. Intestinal obstruction, Reye's syndrome, brain tumor.
11.Safety and efficacy have not been established in children <18 yr.
2.Severe depression
3.Anxiety
4.Obsessive thoughts
2.May reduce the therapeutic effect of anti-Parkinson`s agents (dopamine agonist).
3.Serum levels may be reduced by carbamazepine.
4.Concurrent use may increase toxicity of other CNS depressants.
5.Serum levels may be increased by itraconazole.
6.Lithium may increase neurotoxic effects of paliperidone.
Home Delivery for Paliperidone in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including paliperidone.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for paliperidone and other medicines and health products. Home delivery services for paliperidone may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take paliperidone only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for paliperidone before they complete the sale. You can get this information while placing the order for paliperidone with the pharmacy.
Paliperidone is a generic medicine name and there are several brands available for it. Some of the brands for paliperidone might be better known than paliperidone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have paliperidone in stock, you can ask for one of the branded alternatives for paliperidone.
