Mebeverine Pharmacology


About Mebeverine
Reserpine derivative, antimuscarinic, a musculotropic antispasmodic, Motility stimulant.
Mechanism of Action of Mebeverine
Mebeverine has a direct relaxant effect on smooth muscle. This will inhibits gastrointestinal propulsive motility and gastric acid secretion.
Pharmacokinets of Mebeverine
Absorption: It is well absorbed after oral administration.
Metabolism: Mebeverine is rapidly and extensively undergoes hydrolysis and forms Veratric acid
Excretion: Metabolites are excreted mainly in urine
Onset of Action for Mebeverine
Duration of Action for Mebeverine
Half Life of Mebeverine
1.1 hours
Side Effects of Mebeverine
1.Gastrointestinal disturbances
2.Heart burn
Contra-indications of Mebeverine
1.Hypersensitivity to Mebeverine
Special Precautions while taking Mebeverine
1.Hepatic impairment
2.Renal impairment
3.Heart failure
4.Ischemic heart disease
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Indications for Mebeverine
1.Irritable bowel syndrome
Interactions for Mebeverine
Typical Dosage for Mebeverine
Adult: 405 mg / day in 3- divided doses to be taken 20 minutes before meals. Dose can be gradually reduced after 1 week if sufficient response is obtained.
Children above 10 years: 405 mg / day in 3- divided doses to be taken 20 minutes before meals. Dose can be gradually reduced after 1 week if sufficient response is obtained.
Children below 10 years: contraindicated.
Schedule of Mebeverine
Storage Requirements for Mebeverine
Store in a cool dry place. Protect from heat and light.
Keep out of the reach of children
Effects of Missed Dosage of Mebeverine
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Mebeverine
Give supportive measures and symptomatic treatment.

Home Delivery for Mebeverine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including mebeverine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for mebeverine and other medicines and health products. Home delivery services for mebeverine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take mebeverine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for mebeverine before they complete the sale. You can get this information while placing the order for mebeverine with the pharmacy.

Mebeverine is a generic medicine name and there are several brands available for it. Some of the brands for mebeverine might be better known than mebeverine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have mebeverine in stock, you can ask for one of the branded alternatives for mebeverine.