Epalrestat Pharmacology


About Epalrestat
Aldose reductase inhibitor
Mechanism of Action of Epalrestat
Epalrestat is an aldose reductase inhibitor.Aldose reductase reduses glucose to sorbitol. Epalrestat inhibited high glucose-mediated neutrophil?endothelial cell adhesion and expression of endothelial adhesion molecules not only through inhibition of a PKC-dependent pathway, but also through increased endothelial NO production.
Long-term treatment with epalrestat is well tolerated and can effectively delay the progression of diabetic neuropathy and ameliorate the associated symptoms of the disease, particularly in subjects with good glycemic control and limited microangiopathy
Pharmacokinets of Epalrestat
Onset of Action for Epalrestat
Duration of Action for Epalrestat
Half Life of Epalrestat
Side Effects of Epalrestat
1.Hepatic disfunction
2.Nausea and vomiting
3.Gastric discomfort
Contra-indications of Epalrestat
Special Precautions while taking Epalrestat
Pregnancy Related Information
Old Age Related Information
Breast Feeding Related Information
Children Related Information
Indications for Epalrestat
Diabetic neuropathy
Interactions for Epalrestat
Typical Dosage for Epalrestat
50 mg 3 times/day may improve motor and sensory nerve conduction velocity and subjective neuropathy symptoms.
Schedule of Epalrestat
Storage Requirements for Epalrestat
Effects of Missed Dosage of Epalrestat
Effects of Overdose of Epalrestat

Home Delivery for Epalrestat in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including epalrestat.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for epalrestat and other medicines and health products. Home delivery services for epalrestat may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take epalrestat only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for epalrestat before they complete the sale. You can get this information while placing the order for epalrestat with the pharmacy.

Epalrestat is a generic medicine name and there are several brands available for it. Some of the brands for epalrestat might be better known than epalrestat itself. If the pharmacy that's willing to deliver medicines to your home doesn't have epalrestat in stock, you can ask for one of the branded alternatives for epalrestat.