Citicoline + Piracetam Pharmacology

Citicoline + Piracetam

About Citicoline + Piracetam
N/A
Mechanism of Action of Citicoline + Piracetam
N/A
Pharmacokinets of Citicoline + Piracetam
N/A
Onset of Action for Citicoline + Piracetam
N/A
Duration of Action for Citicoline + Piracetam
N/A
Half Life of Citicoline + Piracetam
N/A
Side Effects of Citicoline + Piracetam
N/A
Contra-indications of Citicoline + Piracetam
N/A
Special Precautions while taking Citicoline + Piracetam
N/A
Pregnancy Related Information
Contra indicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contra indicated
Children Related Information
Safety not established
Indications for Citicoline + Piracetam
1.Head injury
2.Cerebrovascular disorders
3.Parkinsonism
4.As a cognitive enhancer
5.Memory enhancement
Interactions for Citicoline + Piracetam
N/A
Typical Dosage for Citicoline + Piracetam
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Schedule of Citicoline + Piracetam
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Storage Requirements for Citicoline + Piracetam
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Effects of Missed Dosage of Citicoline + Piracetam
N/A
Effects of Overdose of Citicoline + Piracetam
N/A

Citicoline

About Citicoline
Nootropics,Cerebrovascular insult and insufficiancy
Mechanism of Action of Citicoline
Citicoline increases blood flow and O2 consumption in the brain. It is also involved in the biosynthesis of lecithin.Citicoline enhance the synthesis of phosphatidyl-choline in brain but could inhibit destructive process(activation of phospholipases)
Pharmacokinets of Citicoline
Absorption: Absorbed after oral administration
Distribution: Widely distributed in the body,cross the blood brain barrier
Metabolism: Metabolised in the liver
Excretion: Excreted through urine
Onset of Action for Citicoline
N/A
Duration of Action for Citicoline
N/A
Half Life of Citicoline
24 hrs
Side Effects of Citicoline
1.Insomnia
2.Headache
3.Diarrhea
4.High or low blood pressure
5.Nausea
6.Blurred vision
7.Chest pains
Contra-indications of Citicoline
Hypersensitivity to drug
Special Precautions while taking Citicoline
1.Hepatic problem
2.Kidney problem
3.Acute, severe & progressive disturbance of consciousness
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
N/A
Children Related Information
Use with caution
Indications for Citicoline
1.Parkinson?s disease
2.Head injury
3.Cerebral vascular disease
4.Alzheimer?s disease
5.Cerebral surgery or acute cerebral disturbance
6.Disturbance of consciousness following brain surgery
Interactions for Citicoline
Levo Dopa: Increases the effect of levodopa
Typical Dosage for Citicoline
Cerebrovascular disorders and head injury:
Oral: Adult: 200-600 mg daily in divided doses
Parenteral: Up to 1 g IM/IV daily
Parkinsonism:
Oral: 200-600 mg daily in divided doses
Parenteral: Up to 1 g IM/IV daily
Schedule of Citicoline
H
Storage Requirements for Citicoline
Store in a tightly closed container,below 25 dgree C. Keep out of the reach of children
Effects of Missed Dosage of Citicoline
N/A
Effects of Overdose of Citicoline
N/A

Piracetam

About Piracetam
Pyrrolidone derivative, a cyclic derivative of GABA, Nootropic,in cerebrovascular insults and insufficiency.
Mechanism of Action of Piracetam
Piracetam is a cyclic GABA derivative. It facilitates the movement of information between the brain`s 2 hemispheres via corpus callosum and improves the function of Acetylcholine via muscarinic receptors which are implicated in memory process. Piracetam is also called as Nootropics or cognition enhancer.
Piracetam improves the production of adenosine triphosphate (ATP) which is the energy storage and energy generating molecules within our cells. Piracetam increases the blood flow to the brain and promote cerebral metabolism. It increases brain`s use of glucose and oxygen. It also enhances protein synthesis in the brain.
Piracetam enhances the excitatory neurotransmitter NMDA glutamate receptor which is involved in learning and memory process.
Piracetam modulates calcium and potassium ion channels.
Pharmacokinets of Piracetam
Absorption: It is well absorbed after oral administration.
Excretion: It is excreted mainly through urine.
Onset of Action for Piracetam
30 - 60 minutes
Duration of Action for Piracetam
1 day
Half Life of Piracetam
4 - 5 hours
Side Effects of Piracetam
1. Nausea
2. Epigastric distress
3. Skin rash
4. Hyperkinesias
5. Nervousness
6. Depression
7. Diarrhoea
8. Sleep disturbances
9. Dizziness
10. Excitement
11. Insomnia
12. Somnolence
13. Weight gain
Contra-indications of Piracetam
N/A
Special Precautions while taking Piracetam
1. Hepatic impairment
2. Renal impairment
3. Cardiac impairment
4. Slowly withdraw the drug with caution
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
NEONATES : Contraindicated
Indications for Piracetam
1. Mental retardation and Dyslexia in children
2. Senile dementia and confusional states of old age
3. Cerebrovascular accidents
4. To reduce impairment of consciousness following brain surgery
Interactions for Piracetam
Oral anticoagulants: Increased prothrombin time.
Typical Dosage for Piracetam
Adults: Ischemic stroke: 12gm I.V./20 minutes, followed by 12gm I.V./day for 4 weeks or orally.
Post-stroke complications (aphasia/hemiplegia): 4.8gm/day for 8 weeks.
Age associated problems (memory lapses, vertigo, concentration gap): 2.4-4.8 gm/day for 12 weeks
Learning difficulties: 3 gm/day in 3 divided doses for 1 school year.
Children: 50 mg/kg body weight in 3 separate doses. Once the desired result has been obtained reduce the initial dose by half upto 6-8 weeks.
Schedule of Piracetam
H
Storage Requirements for Piracetam
Store below 25 degree C in tightly closed container moisture. Protect from moisture. Keep out of the reach of children.
Effects of Missed Dosage of Piracetam
Take the missed dose as soon as noticed. If it is the time for next dose then skip the missed dose and take that dose. Do not double the dose. Continue the regular schedule.
Effects of Overdose of Piracetam
Give supportive measures and symptomatic treatment. Drug can be removed from the body by forced diuresis. In renal insufficiency drug can be removed by dialysis.

Home Delivery for Citicoline + Piracetam in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for citicoline + piracetam and other medicines and health products. Home delivery services for citicoline + piracetam may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Citicoline + Piracetam is a generic medicine name and there are several brands available for it. Some of the brands for citicoline + piracetam might be better known than citicoline + piracetam itself. If the pharmacy that's willing to deliver medicines to your home doesn't have citicoline + piracetam in stock, you can ask for one of the branded alternatives for citicoline + piracetam.