Cilnidipine Pharmacology

Cilnidipine

About Cilnidipine
Dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects.
Mechanism of Action of Cilnidipine
Cilnidipine is a dihydropyridine calcium-channel blocker. It inhibits cellular influx of calcium, thus causing vasodilatation. It has greater selectivity for vascular smooth muscle. It has little or no action at the SA or AV nodes and -ve inotropic activity is rarely seen at therapeutic doses.
Pharmacokinets of Cilnidipine
Metabolism:Hepatic
Onset of Action for Cilnidipine
N/A
Duration of Action for Cilnidipine
N/A
Half Life of Cilnidipine
N/A
Side Effects of Cilnidipine
1.Dizziness
2.Flushing
3.Headache
4.Hypotension
5.Peripheral oedema
6.Tachycardia
7.Palpitations
8.GI disturbances
9.Increased micturition frequency
10.Lethargy
11.Eye pain
12.Depression
13.Ischaemic chest pain
14.Cerebral or myocardial ischaemia
15.Transient blindness
16.Rashes
17.Fever
18.Abnormal liver function
19.Gingival hyperplasia
20Myalgia
21.Tremor
22.Impotence.

Contra-indications of Cilnidipine
1.Cardiogenic shock
2.Recent MI or acute unstable angina
3.Severe aortic stenosis
4.Hyper sensitivity
Special Precautions while taking Cilnidipine
1.Hypotension
2.Poor cardiac reserve
3.Heart failure
4.Sudden withdrawal may exacerbate angina
5.Discontinue in patients who experience ischemic pain following administration
Pregnancy Related Information
Use with caution
Old Age Related Information
N/A
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Cilnidipine
Hypertension with or without cardiac failure.
Interactions for Cilnidipine
1.Other antihypertensives
2.Aldesleukin
3.Antipsychotics that cause hypotension
4.May modify insulin and glucose responses
5.Quinidine
6.Carbamazepine
7.Phenytoin
8.Rifampicin
9.Cimetidine
10.Erythromycin.
Typical Dosage for Cilnidipine
Adult: 5-10 mg once daily, increase to 20 mg once daily if necessary.
Schedule of Cilnidipine
N/A
Storage Requirements for Cilnidipine
N/A
Effects of Missed Dosage of Cilnidipine
N/A
Effects of Overdose of Cilnidipine
N/A

Home Delivery for Cilnidipine in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cilnidipine.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cilnidipine and other medicines and health products. Home delivery services for cilnidipine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take cilnidipine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cilnidipine before they complete the sale. You can get this information while placing the order for cilnidipine with the pharmacy.

Cilnidipine is a generic medicine name and there are several brands available for it. Some of the brands for cilnidipine might be better known than cilnidipine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cilnidipine in stock, you can ask for one of the branded alternatives for cilnidipine.