2.Distribution: Protein binding Very high (93%)
3.Metabolism:Extensively metabolized (gastrointestinal and hepatic)
4.Elimination: Excreted primarily as glucuronides via the kidney, Some unchanged drug is removed in the bile and faeces.
3.Severe liver disease
4.Use with monoamine oxidase inhibitors
2.History of epilepsy
6.History of mania
9.History of urinary retention
10.Concurrent electroconvulsive therapy
12.Unsafe for use in patients with porphyria
13.Avoid abrupt withdrawal
14.May cause drowsiness
15.Do not drive or operate machinery
16.Treatment for more than 2-3 wk is not recommended.
17.Avoid alcohole intake
2.Increased risk of serotonin syndrome when cyclobenzaprine was taken with the serotonergic drugs duloxetine or phenelzine.
3.Plasma concentration may be increased with the use of cimetidine, diltiazem, disulfiram, methylphenidate, ritonavir, and verapamil.
4.Side-effects are increased by adrenaline, amiodarone, general anesthetics, SSRIs, antihistamines, antimuscarinics, antipsychotics, anxiolytics and hypnotics, clozapine, disopyramide, diuretics, flecainide, moclobemide, moxifloxacin, nefopam, nicorandil, noradrenaline, phenothiazine, pimozide, procainamide, propafenone, quinidine, selegiline, sibutramine, sotalol, terfenadine, thioridazine, and tramadol.
5.Effects of adrenergic neurone blockers, clonidine, barbiturates, nitrates, and primidone are reduced
6.Effects of baclofen, opioid analgesics, and thyroid hormones are enhanced with concomitant use of cyclobenzaprine.
7.Carbamazepine and rifampicin may increase metabolism of cyclobenzaprine.
8.Effects may be antagonized by oestrogens.
9. Avoid use with brimonidine, entacapone, artemether with lumefantrine, or sibutramine.
CNS effects may be enhanced by other CNS depressants.
2.Overdose symptoms may include drowsiness, fast heartbeat, tremors or shaking, slurred speech, confusion, nausea, vomiting, hallucinations, chest pain, or seizure (convulsions).
Home Delivery for Cyclobenzaprine in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cyclobenzaprine.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cyclobenzaprine and other medicines and health products. Home delivery services for cyclobenzaprine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take cyclobenzaprine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cyclobenzaprine before they complete the sale. You can get this information while placing the order for cyclobenzaprine with the pharmacy.
Cyclobenzaprine is a generic medicine name and there are several brands available for it. Some of the brands for cyclobenzaprine might be better known than cyclobenzaprine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cyclobenzaprine in stock, you can ask for one of the branded alternatives for cyclobenzaprine.