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- Generic Medicines
- Pharmacology For Cloxacillin
CloxacillinAbout CloxacillinIt is a Penicillinase resistant Penicillin, Penicillin derived antibiotic.Mechanism of Action of CloxacillinCloxacillin is a bactericidal drug. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. In addition to this it is not degraded by penicillinase enzyme and therefore it can be useful against penicillinase producing bacteria also.Pharmacokinets of CloxacillinAbsorption .It is readily absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: It does not undergo metabolism. Excretion: It is excreted mainly through urine and small amount excreted through breast milk.Onset of Action for Cloxacillin30-60 minutesDuration of Action for CloxacillinAbout 6 hoursHalf Life of Cloxacillin30 minutesSide Effects of Cloxacillin1.Anaphylaxis
Contra-indications of CloxacillinHypersensitive to Cloxacillin or other Penicillins.Special Precautions while taking Cloxacillin1.Heart failure
4 Bleeding tendencies
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Cloxacillin1.Urinary tract infections
2.Respiratory tract infections
Interactions for CloxacillinOral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Atenolol: Bio-availability of atenolol reduced.
Allopurinol: Increases risk of cloxacillin induced skin rash.
Probenecid: Increases blood levels.
Erythromycin & Tetracyclines: Reduce efficacy.
Clavulanic Acid: Synergy.
Food: Interferes with absorptionTypical Dosage for CloxacillinADULT
1 - 2 g daily in four divided dose depending on the severity of infection
50 - 100 mg/kg/day in four divided dose depending on the severity of infection
Schedule of CloxacillinHStorage Requirements for CloxacillinThe vial should be stored in room temperature away from heat and moisture. Keep out of the reach of childrenEffects of Missed Dosage of CloxacillinTake the dose as soon as noticed and if it is the time to the next dose then skip the missed doseEffects of Overdose of CloxacillinGive supportive measures and symptomatic treatment. Absorption of drug can be reduced by gastric lavage or induction of emesis
Home Delivery for Cloxacillin in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including cloxacillin.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for cloxacillin and other medicines and health products. Home delivery services for cloxacillin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take cloxacillin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for cloxacillin before they complete the sale. You can get this information while placing the order for cloxacillin with the pharmacy.
Cloxacillin is a generic medicine name and there are several brands available for it. Some of the brands for cloxacillin might be better known than cloxacillin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have cloxacillin in stock, you can ask for one of the branded alternatives for cloxacillin.