Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin Pharmacology

Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin

About Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Mechanism of Action of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Pharmacokinets of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Onset of Action for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Duration of Action for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Half Life of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Side Effects of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
1.Constipation
2.Diarrhea
3.Upset stomach may occur
4.Black stools
5.Rarely allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing
Contra-indications of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Special Precautions while taking Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
1.Allergic to any of its ingredients
2.Certain metabolic disorders (e.g., hemochromatosis, hemosiderosis)
3.Stomach/intestinal problems (e.g., ulcers, colitis), vitamin B12 deficiency (pernicious anemia)
Pregnancy Related Information
Use with cution
Old Age Related Information
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Breast Feeding Related Information
Use with cution
Children Related Information
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Indications for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
1.It is used to treat or prevent a lack of these nutrients which may occur in certain health conditions (e.g., anemia, pregnancy, poor diet, surgery recovery)
2.Treatment of iron deficiency anaemia
Interactions for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
This can decrease the absorption of other drugs such as bisphosphonates (for example, alendronate), levodopa, penicillamine, quinolone antibiotics (for example, ciprofloxacin, levofloxacin), thyroid medications (for example, levothyroxine), and tetracycline antibiotics (for example, doxycycline, minocycline)
Typical Dosage for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
This medication is best taken on an empty stomach 1 hour before or 2 hours after meals.
Schedule of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
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Storage Requirements for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Properly discard this product when it is expired or no longer needed.
Effects of Missed Dosage of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Effects of Overdose of Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years. Keep this product out of reach of children. If overdose does occur, seek immediate medical attention.

Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
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Side Effects of Folic Acid
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Contra-indications of Folic Acid
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Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Zinc Ascorbate

About Zinc Ascorbate
Zinc ascorbate is an antioxidant mineral and an immune booster.
Mechanism of Action of Zinc Ascorbate
While the antioxidant activity of ascobic acid, also known as Vitamin C, is enhanced when zinc is present, zinc itself plays an important role in our immune system and other metabolic processes. Zinc ascorbate can also be better absorbed than the inorganic zinc salts. It also has greater tissue retention and is gentler on the system. Our body does contain a large number of zinc deposits in bones and muscles, but these are not readily available for use in cell growth. Under conditions where zinc is readily available, it is subject to high turnover rates, leading to deficiency if supply is not supplmented.
Pharmacokinets of Zinc Ascorbate
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Onset of Action for Zinc Ascorbate
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Duration of Action for Zinc Ascorbate
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Half Life of Zinc Ascorbate
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Side Effects of Zinc Ascorbate
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Contra-indications of Zinc Ascorbate
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Special Precautions while taking Zinc Ascorbate
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Pregnancy Related Information
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Old Age Related Information
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Breast Feeding Related Information
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Children Related Information
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Indications for Zinc Ascorbate
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Interactions for Zinc Ascorbate
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Typical Dosage for Zinc Ascorbate
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Schedule of Zinc Ascorbate
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Storage Requirements for Zinc Ascorbate
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Effects of Missed Dosage of Zinc Ascorbate
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Effects of Overdose of Zinc Ascorbate
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Iron (Carbonyl Iron)

About Iron (Carbonyl Iron)
A highly pure, nontoxic Iron(a minimum 98% iron content), Iron dietary supplement and to treat iron deficiency.
Mechanism of Action of Iron (Carbonyl Iron)
Iron formulations exerts haematinic action by being an essential constituent of haemoglobin. It is necessary for the oxidative process of living tissues.
Pharmacokinets of Iron (Carbonyl Iron)
Absorption: Absorbed orally in ferrous form and poorly absorbed in healthy individuals (about 10%) but in patients suffering from iron deficiency anaemia up to 60% dose is absorbed.
Distribution: Transported in a transferrin bound form in to bone marrow for incorporation in to haemoglobin.
Metabolism: Iron liberated by destruction of haemoglobin is reused by the body.
Excretion: Excretion of iron is minimal. Loss usually occurs in nails, faeces, urine, hair, sweat, and bile.
Onset of Action for Iron (Carbonyl Iron)
4 days
Duration of Action for Iron (Carbonyl Iron)
2 to 4 months
Half Life of Iron (Carbonyl Iron)
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Side Effects of Iron (Carbonyl Iron)
1. Nausea
2. Epigasttric distress
3. Vomiting
4. Constipation
5. Diarrhoea
6. Black stools
7. Temporary staining of teeth with liquid formulations
Contra-indications of Iron (Carbonyl Iron)
1. Haemolytic anaemia unless iron deficiency anaemia is also present
2. Haemochromatosis
3. Haemosiderosis
4. Peptic ulcer
5. Regional enteritis
6. Ulcerative colitis
7. Those receiving repeated blood transfusions
Special Precautions while taking Iron (Carbonyl Iron)
1. Prolonged use
2. Minimise gastrointestinal discomfort by taking along with meals and gradually increasing the recommended dosage
3. Discontinue if intolerance occurs
4. Higher doses are required for geriatric patients
Pregnancy Related Information
May be used
Old Age Related Information
Use with caution
Breast Feeding Related Information
May be used
Children Related Information
Use with caution
Indications for Iron (Carbonyl Iron)
1. Iron deficiency
2. Iron deficiency during pregnancy and lactation
3. Iron deficiency in infants and children
Interactions for Iron (Carbonyl Iron)
(Oral Iron): Antacids: GI absorption of iron reduced.
Ascorbic acid: GI absorption of iron enhanced.
Chloramphenicol: Serum iron levels may be increased.
Cimetidine: GI absorption may be reduced.
Levodopa: Decreased levodopa serum levels.
Methyldopa: May result in decreased efficacy of methyldopa.
Quinolones: GI absorption of quinolones decreased.
Penicillamine: Marked reduction in GI absorption of penicillamine.
Tetracyclines: Decrease in the absorption of both tetracyclines and iron salts.
Food: Eggs and milk inhibit iron absorption. Administration of calcium and iron supplementation with food reduces ferrous sulfate absorption by one-third. If combined iron and calcium supplementation required then calcium carbonate should be used and the supplementation taken between meals.
Typical Dosage for Iron (Carbonyl Iron)
Oral:
Ferrous fumarate:
Adults: Starts with 50 to 100mg 2 to 3 times daily. Adjust the dosage based on patient`s response.
Children: 4 to 6mg/kg daily in three divided doses.
Ferrous sulphate:
Adults: 100 to 300mg; twice daily. Increases the dosage based on patient`s response if required up to 300mg 4 times daily.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Ferrous gluconate:
300 to 1200mg daily in three to four divided doses.
Children (age 2 to 12): 3mg/kg/day in three to four divided doses
Children (age 6months to 2years): 3 to 6mg/kg/day in three to four divided doses
Infants: 10 to 25mg/day in three to four divided doses.
Schedule of Iron (Carbonyl Iron)
H
Storage Requirements for Iron (Carbonyl Iron)
Store in a well closed container in a cool dry place. Protect from light.
Effects of Missed Dosage of Iron (Carbonyl Iron)
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Iron (Carbonyl Iron)
Treatment includes immediate support of airway, respiration, and circulation. In conscious patients induce emesis with ipecac; if not empty stomach by gastric lavage. Follow emesis with lavage, using a 1% sodium bicarbonate solution to convert iron to less irritating poorly absorbed form. Take abdominal X-ray to determine presence of excess iron. Deferoxamine may be used for systemic chelation if serum levels of iron exceed 350mg/dl.

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Special Precautions while taking
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Home Delivery for Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin in Your City

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Folic Acid + Zinc Ascorbate + Iron (Carbonyl Iron) + Adenosyl Cobalamin is a generic medicine name and there are several brands available for it. Some of the brands for folic acid + zinc ascorbate + iron (carbonyl iron) + adenosyl cobalamin might be better known than folic acid + zinc ascorbate + iron (carbonyl iron) + adenosyl cobalamin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have folic acid + zinc ascorbate + iron (carbonyl iron) + adenosyl cobalamin in stock, you can ask for one of the branded alternatives for folic acid + zinc ascorbate + iron (carbonyl iron) + adenosyl cobalamin.