Human Normal Immunoglobulin Pharmacology

Human Normal Immunoglobulin

About Human Normal Immunoglobulin
Protein(antibody) , passive immunizing agent, Immune globulin(Eg: hepatitis A ,measles prophylaxis),Hypogammaglobulinaemia.
Mechanism of Action of Human Normal Immunoglobulin
Normal immunoglobulin is an extract of human (donor) blood which contains antibodies to diseases e.g. hepatitis A, measles, mumps, and German measles (rubella)
Pharmacokinets of Human Normal Immunoglobulin
Onset of Action for Human Normal Immunoglobulin
Duration of Action for Human Normal Immunoglobulin
Half Life of Human Normal Immunoglobulin
Side Effects of Human Normal Immunoglobulin
1. Rash
2. Fever (pyrexia)
3. Chills
4. Itching (pruritis)
5. Redness around injection site
6. Hardening of skin around injection site
7. Increased heart rate (tachycardia)
8. Malaise
9. Pain and swelling at site of injection
Contra-indications of Human Normal Immunoglobulin
1. Hyper sensitivity to it
2. Vaccination with a live vaccine (e.g. oral polio, MMR) at the same time or in the previous 3 weeks
3. Immunoglobulin A (IgA) deficiency
4. Thrombocytopenia
5. Coagulation disorder
Special Precautions while taking Human Normal Immunoglobulin
Use with caution in patients with a history of prior systemic allergic reactions following the administration of human immunoglobulin preparations.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Human Normal Immunoglobulin
1. Preventing infection following burns injuries
2. Prevention of German measles following exposure in pregnancy
3. Prevention of Hepatitis A
4. Prevention of measles or reduction in measles symptoms following exposure in susceptible people
5. Reducing number and severity of infections in people with low levels of immunoglobulins in their blood
6. Agammaglobulinaemia/hypogammaglobulinaemia/dysgammaglobulinaemia
Interactions for Human Normal Immunoglobulin
Typical Dosage for Human Normal Immunoglobulin
Adults and children-
Hepatitis A
0.06 mL/kg bodyweight should be given for long term protection 0.03 mL/kg bodyweight for short term protection.
For prophylaxis long term, the injections should be given 5 monthly but serological checks should be made to assess if active immunity has developed.
The following doses of Normal Immunoglobulin are recommended for persons who plan to travel in areas where hepatitis A is common
Length of stay <3 months- 0.03 mL/kg bodyweight 3 months or longer - 0.06 mL/kg bodyweight (repeat every 4-6 months)
Institutional contacts- 0.06 mL/kg bodyweight.
Staff in institutions where hepatitis is endemic- A large dose (0.06 mL/kg bodyweight) should be given at the time of employment, and this should be repeated at six-monthly intervals if the risk persists.
Measles- 0.2 mL/kg bodyweight for prevention.
Poliomyelitis- 0.3 mL/kg bodyweight.
Hypogammaglobulinaemia- 0.6 mL/kg bodyweight at intervals of one month. An additional dose should be given during the first month of treatment
Schedule of Human Normal Immunoglobulin
Storage Requirements for Human Normal Immunoglobulin
Store at 2?C to 8?C (Refrigerate. Do not freeze). Protect from light
Effects of Missed Dosage of Human Normal Immunoglobulin
The doctor should be informed immediately if a dose is missed
Effects of Overdose of Human Normal Immunoglobulin
Give symptomatic and supportive treatment

Home Delivery for Human Normal Immunoglobulin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including human normal immunoglobulin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for human normal immunoglobulin and other medicines and health products. Home delivery services for human normal immunoglobulin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take human normal immunoglobulin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for human normal immunoglobulin before they complete the sale. You can get this information while placing the order for human normal immunoglobulin with the pharmacy.

Human Normal Immunoglobulin is a generic medicine name and there are several brands available for it. Some of the brands for human normal immunoglobulin might be better known than human normal immunoglobulin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have human normal immunoglobulin in stock, you can ask for one of the branded alternatives for human normal immunoglobulin.