Clotrimazole + Lignocaine Pharmacology

Clotrimazole + Lignocaine

About Clotrimazole + Lignocaine
N/A
Mechanism of Action of Clotrimazole + Lignocaine
It binds to phospholipids in the fungal (inhibiting fungal sterol synthesis) cell membrane altering cell wall permeability resulting in loss of essential intracellular elements. It is broad spectrum anti-fungal agent that inhibits the growth of most fungi pathogens to man.
Lignocaine, which is a local anesthetic that helps to relieve pain caused by ear infections.
Pharmacokinets of Clotrimazole + Lignocaine
N/A
Onset of Action for Clotrimazole + Lignocaine
N/A
Duration of Action for Clotrimazole + Lignocaine
N/A
Half Life of Clotrimazole + Lignocaine
N/A
Side Effects of Clotrimazole + Lignocaine
N/A
Contra-indications of Clotrimazole + Lignocaine
N/A
Special Precautions while taking Clotrimazole + Lignocaine
N/A
Pregnancy Related Information
May be used
Old Age Related Information
N/A
Breast Feeding Related Information
Use with caution,donot apply to nipples.
Children Related Information
N/A
Indications for Clotrimazole + Lignocaine
Fungal infections of the middle ear and outer ear.
Interactions for Clotrimazole + Lignocaine
N/A
Typical Dosage for Clotrimazole + Lignocaine
N/A
Schedule of Clotrimazole + Lignocaine
N/A
Storage Requirements for Clotrimazole + Lignocaine
N/A
Effects of Missed Dosage of Clotrimazole + Lignocaine
N/A
Effects of Overdose of Clotrimazole + Lignocaine
N/A

Clotrimazole

About Clotrimazole
A broad-spectrum antifungal antibiotic, imidazole derivative, Oral Nonabsorbed Antifungal Agent.
Mechanism of Action of Clotrimazole
Clotrimazole is fungicidal or fungistatic depending on the drug concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis which is an essential constituent of cell membrane. Inhibition of ergosterol synthesis will alter the membrane permeability of the susceptible fungus and kill or inhibit them.
Pharmacokinets of Clotrimazole
Absorption: Absorption is minimal after topical administration.
Onset of Action for Clotrimazole
N/A
Duration of Action for Clotrimazole
3 hours
Half Life of Clotrimazole
N/A
Side Effects of Clotrimazole
1.Stinging
2.Erythema
3.Burning
4.Pruritis
5.Vesication
6.Desquamation
7.Urticaria
8.Burning
9.Peeling
10.Irritation
Contra-indications of Clotrimazole
Hypersensitivity to Clotrimazole
Special Precautions while taking Clotrimazole
1.Avoid contact with eyes, nose and mouth.
2.Do not wear occlusive dress over the medicament.
Pregnancy Related Information
Use with caution.
Old Age Related Information
Use with caution.
Breast Feeding Related Information
Use with caution.
Children Related Information
Use with caution.
NEONATES: contraindicated
Indications for Clotrimazole
1.Tinea pedis
2.Tinea cruris
3.Tinea versicolor
4.Tinea corporis
5.Cutaneous candidiasis
6.Vulvovaginal candidiasis
Interactions for Clotrimazole
Polyene Antibiotics : Antagonises effects of polyene antibiotics.
Typical Dosage for Clotrimazole
Topical: Clotrimazole cream, lotion and solution 1 % is used.
Clean and dry the affected area and apply the medicament with gentle massage 2 -3 times daily for 2 - 4 weeks.
Vaginal candidiasis: Insert 1 applicator full (vaginal cream 1%) intravaginally at night for 1 -2 weeks.
Vaginal tablets 100. 200 and 500mg tablet is available.
Vulvovaginal candidiasis: Insert 100mg tablet intravaginally at bed time for 7 consecutive days or 200 mg tablet for 3 consecutive days or 500 mg tablet for 1 day at night.
Oral lozenge 10 mg is available
Oropharyngeal candidiasis: 1 lozenge orally 5 times daily for 2 weeks
Prophylaxis of Oropharyngeal candidiasis: 1 lozenge is used 3 times daily
Gel: Insert with an applicator intravaginally at night for 1 - 2 weeks.
Powder (1% w/ w): dusted over the body parts as required
Schedule of Clotrimazole
H
Storage Requirements for Clotrimazole
Store at room temperature (15 - 25 degree C). Protect from heat and moisture. Keep out of the reach of children
Effects of Missed Dosage of Clotrimazole
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Clotrimazole
Give supportive measures and symptomatic treatment.

Lignocaine

About Lignocaine
Lincosamide antibiotic , Antibiotic.
Mechanism of Action of Lignocaine
N/A
Pharmacokinets of Lignocaine
N/A
Onset of Action for Lignocaine
N/A
Duration of Action for Lignocaine
N/A
Half Life of Lignocaine
N/A
Side Effects of Lignocaine
N/A
Contra-indications of Lignocaine
N/A
Special Precautions while taking Lignocaine
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Lignocaine
N/A
Interactions for Lignocaine
N/A
Typical Dosage for Lignocaine
N/A
Schedule of Lignocaine
N/A
Storage Requirements for Lignocaine
N/A
Effects of Missed Dosage of Lignocaine
N/A
Effects of Overdose of Lignocaine
N/A

Home Delivery for Clotrimazole + Lignocaine in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for clotrimazole + lignocaine and other medicines and health products. Home delivery services for clotrimazole + lignocaine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take clotrimazole + lignocaine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for clotrimazole + lignocaine before they complete the sale. You can get this information while placing the order for clotrimazole + lignocaine with the pharmacy.

Clotrimazole + Lignocaine is a generic medicine name and there are several brands available for it. Some of the brands for clotrimazole + lignocaine might be better known than clotrimazole + lignocaine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clotrimazole + lignocaine in stock, you can ask for one of the branded alternatives for clotrimazole + lignocaine.