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- Pharmacology For Clotrimazole + Lignocaine
Clotrimazole + Lignocaine Pharmacology
Clotrimazole + LignocaineAbout Clotrimazole + LignocaineN/AMechanism of Action of Clotrimazole + LignocaineIt binds to phospholipids in the fungal (inhibiting fungal sterol synthesis) cell membrane altering cell wall permeability resulting in loss of essential intracellular elements. It is broad spectrum anti-fungal agent that inhibits the growth of most fungi pathogens to man.
Lignocaine, which is a local anesthetic that helps to relieve pain caused by ear infections.
Pharmacokinets of Clotrimazole + LignocaineN/AOnset of Action for Clotrimazole + LignocaineN/ADuration of Action for Clotrimazole + LignocaineN/AHalf Life of Clotrimazole + LignocaineN/ASide Effects of Clotrimazole + LignocaineN/AContra-indications of Clotrimazole + LignocaineN/ASpecial Precautions while taking Clotrimazole + LignocaineN/APregnancy Related InformationMay be usedOld Age Related InformationN/ABreast Feeding Related InformationUse with caution,donot apply to nipples.Children Related InformationN/AIndications for Clotrimazole + LignocaineFungal infections of the middle ear and outer ear.Interactions for Clotrimazole + LignocaineN/ATypical Dosage for Clotrimazole + LignocaineN/ASchedule of Clotrimazole + LignocaineN/AStorage Requirements for Clotrimazole + LignocaineN/AEffects of Missed Dosage of Clotrimazole + LignocaineN/AEffects of Overdose of Clotrimazole + LignocaineN/A
ClotrimazoleAbout ClotrimazoleA broad-spectrum antifungal antibiotic, imidazole derivative, Oral Nonabsorbed Antifungal Agent.Mechanism of Action of ClotrimazoleClotrimazole is fungicidal or fungistatic depending on the drug concentrations. It inhibits the conversion of Lanosterol to 14 demethyl Lanosterol by inhibiting the cytochromeP450 enzyme 14 alpha demethylase and impair ergosterol synthesis which is an essential constituent of cell membrane. Inhibition of ergosterol synthesis will alter the membrane permeability of the susceptible fungus and kill or inhibit them.Pharmacokinets of ClotrimazoleAbsorption: Absorption is minimal after topical administration.Onset of Action for ClotrimazoleN/ADuration of Action for Clotrimazole3 hoursHalf Life of ClotrimazoleN/ASide Effects of Clotrimazole1.Stinging
Contra-indications of ClotrimazoleHypersensitivity to ClotrimazoleSpecial Precautions while taking Clotrimazole1.Avoid contact with eyes, nose and mouth.
2.Do not wear occlusive dress over the medicament.
Pregnancy Related InformationUse with caution.Old Age Related InformationUse with caution.Breast Feeding Related InformationUse with caution.Children Related InformationUse with caution.
NEONATES: contraindicatedIndications for Clotrimazole1.Tinea pedis
Interactions for ClotrimazolePolyene Antibiotics : Antagonises effects of polyene antibiotics.Typical Dosage for ClotrimazoleTopical: Clotrimazole cream, lotion and solution 1 % is used.
Clean and dry the affected area and apply the medicament with gentle massage 2 -3 times daily for 2 - 4 weeks.
Vaginal candidiasis: Insert 1 applicator full (vaginal cream 1%) intravaginally at night for 1 -2 weeks.
Vaginal tablets 100. 200 and 500mg tablet is available.
Vulvovaginal candidiasis: Insert 100mg tablet intravaginally at bed time for 7 consecutive days or 200 mg tablet for 3 consecutive days or 500 mg tablet for 1 day at night.
Oral lozenge 10 mg is available
Oropharyngeal candidiasis: 1 lozenge orally 5 times daily for 2 weeks
Prophylaxis of Oropharyngeal candidiasis: 1 lozenge is used 3 times daily
Gel: Insert with an applicator intravaginally at night for 1 - 2 weeks.
Powder (1% w/ w): dusted over the body parts as required
Schedule of ClotrimazoleHStorage Requirements for ClotrimazoleStore at room temperature (15 - 25 degree C). Protect from heat and moisture. Keep out of the reach of childrenEffects of Missed Dosage of ClotrimazoleApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ClotrimazoleGive supportive measures and symptomatic treatment.
LignocaineAbout LignocaineLincosamide antibiotic , Antibiotic.Mechanism of Action of LignocaineN/APharmacokinets of LignocaineN/AOnset of Action for LignocaineN/ADuration of Action for LignocaineN/AHalf Life of LignocaineN/ASide Effects of LignocaineN/AContra-indications of LignocaineN/ASpecial Precautions while taking LignocaineN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for LignocaineN/AInteractions for LignocaineN/ATypical Dosage for LignocaineN/ASchedule of LignocaineN/AStorage Requirements for LignocaineN/AEffects of Missed Dosage of LignocaineN/AEffects of Overdose of LignocaineN/A
Home Delivery for Clotrimazole + Lignocaine in Your City
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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for clotrimazole + lignocaine and other medicines and health products. Home delivery services for clotrimazole + lignocaine may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take clotrimazole + lignocaine only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for clotrimazole + lignocaine before they complete the sale. You can get this information while placing the order for clotrimazole + lignocaine with the pharmacy.
Clotrimazole + Lignocaine is a generic medicine name and there are several brands available for it. Some of the brands for clotrimazole + lignocaine might be better known than clotrimazole + lignocaine itself. If the pharmacy that's willing to deliver medicines to your home doesn't have clotrimazole + lignocaine in stock, you can ask for one of the branded alternatives for clotrimazole + lignocaine.