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- Pharmacology For Mometasone + Salicylic Acid
Mometasone + Salicylic Acid Pharmacology
Mometasone + Salicylic Acid
About Mometasone + Salicylic AcidN/AMechanism of Action of Mometasone + Salicylic AcidN/APharmacokinets of Mometasone + Salicylic AcidN/AOnset of Action for Mometasone + Salicylic AcidN/ADuration of Action for Mometasone + Salicylic AcidN/AHalf Life of Mometasone + Salicylic AcidN/ASide Effects of Mometasone + Salicylic AcidN/AContra-indications of Mometasone + Salicylic AcidN/ASpecial Precautions while taking Mometasone + Salicylic AcidN/APregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES:Contra indicatedIndications for Mometasone + Salicylic Acid1.Psoariasis
2.Eczema
3.Dry,scaly,inflamed skin conditions
Interactions for Mometasone + Salicylic AcidN/ATypical Dosage for Mometasone + Salicylic AcidApply the medicament twice daily to the affected part.Schedule of Mometasone + Salicylic AcidN/AStorage Requirements for Mometasone + Salicylic AcidN/AEffects of Missed Dosage of Mometasone + Salicylic AcidN/AEffects of Overdose of Mometasone + Salicylic AcidN/AMometasone
About MometasoneA glucocorticoid steroid, Anti psoriatic,anti asthma ,anti inflammatory.Mechanism of Action of MometasoneMometasone is a topical medium potency glucocorticoid. The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of MometasoneAbsorption: Mometasone is absorbed through intact skin after topical administration and the amount absorbed is depending on the type of inflammation, vehicle used, area of skin and the epidermal barrier. Absorption is increased in inflammation, occlusion and skin damage.Onset of Action for MometasoneN/ADuration of Action for MometasoneN/AHalf Life of MometasoneN/ASide Effects of Mometasone1.Thinning of epidermis
2.Burning
3.Itching
4.Irritation
5.Atrophy (Dermal changes)
6.Telangiectasia
7.Striae
8.Hypopigmentation
9.Contact dermatitis
10.Perioral dermatitis
11.Cataract, Glaucoma, Corneal ulcers caused by application around eyelids and surrounding skin
12.Dry skin
13.Stinging
14.TinglingContra-indications of Mometasone1.Hypersensitivity to Mometasone and other corticosteroids
2.Acne vulgaris
3.Acne Rosacea
5.Tuberculosis infection of the skin
6.Viral, fungal or bacterial primary infections
7.UlcersSpecial Precautions while taking Mometasone1.Avoid the use of medicament if irritation or hypersensitivity occurs
2.Prolonged use
3.Psoriasis
4.Avoid contact with eyes
5.Avoid occlusive dressing
6.Not used more than 5 days on the face or in the children
7.Withdraw gradually after prolonged use
8.Use caution on areas where the skin creases, such as armpits, knees, and elbows
9.Avoid application on large surface areaPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: contraindicated
Indications for Mometasone1.Otitis externa
2 Eczema
3.Dermatoses (secondary infected)
4.Psoriasis
5.Neuro dermatitis
6.Intertrigo
7.Lichen planus
8.Anal and vulval pruritisInteractions for MometasoneN/ATypical Dosage for MometasoneTopical: Mometasone Furoate 0.1 % cream, ointment or lotion is used.
Clean the affected area and wash with warm water and then dry. Apply 2 - 3 times daily for 2 weeks with gentle massage.
Schedule of MometasoneHStorage Requirements for MometasoneStore at room temperature. Protect from heat and light. Keep the container tightly closed. Keep out of the reach of childrenEffects of Missed Dosage of MometasoneApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of MometasoneGive supportive measures and symptomatic treatment.
Salicylic Acid
About Salicylic AcidA beta hydroxy acid, Keratolytic, Topical Skin Product(Anti Acne).Mechanism of Action of Salicylic AcidIt is a keratolytic agent. It encourages exfoliation of the skin and opening up of the plugged follicles, which helps re-establish the normal skin- cell replacement cycle. For milder acne, salicylic acid helps unclog pores to resolve and prevent lesions.Pharmacokinets of Salicylic AcidN/AOnset of Action for Salicylic AcidN/ADuration of Action for Salicylic AcidN/AHalf Life of Salicylic AcidN/ASide Effects of Salicylic Acid1.Allergic reaction
2.Hives
3.Difficulty breathing
4.Swelling of your face, lips, tongue, or throat.
Contra-indications of Salicylic Acid1.Hypersensitivity to Salicylic acidSpecial Precautions while taking Salicylic Acid1.Avoid contact with eyes, mouth, or nose.
2.Like many other topical acne treatments, salicylic acid must be used continuously, even after acne lesions have.Pregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Salicylic Acid1.Treats skin irritation and inflammation caused by burns, insect bites, fungal infections, and eczema.Interactions for Salicylic AcidN/ATypical Dosage for Salicylic AcidUse this medication twice daily Schedule of Salicylic AcidN/AStorage Requirements for Salicylic AcidStore in a cool dry place. Protect from heat and light. Keep out of the reach of childrenEffects of Missed Dosage of Salicylic AcidApply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of Salicylic AcidGive supportive measures and symptomatic treatment.Home Delivery for Mometasone + Salicylic Acid in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including mometasone + salicylic acid.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for mometasone + salicylic acid and other medicines and health products. Home delivery services for mometasone + salicylic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take mometasone + salicylic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for mometasone + salicylic acid before they complete the sale. You can get this information while placing the order for mometasone + salicylic acid with the pharmacy.
Mometasone + Salicylic Acid is a generic medicine name and there are several brands available for it. Some of the brands for mometasone + salicylic acid might be better known than mometasone + salicylic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have mometasone + salicylic acid in stock, you can ask for one of the branded alternatives for mometasone + salicylic acid.
