Rutin Pharmacology

Rutin

About Rutin

Glycoside between the flavonol quercetin and the disaccharide rutinose. Rutin may have antioxidant, anti-inflammatory, anticarcinogenic, antithrombotic,cytoprotective and vasoprotective activities.

Mechanism of Action of Rutin

1.Rutin inhibits platelet aggregation, as well as decreasing capillary permeability, making the blood thinner and improving circulation.
2.Rutin shows anti-inflammatory activity in some animal and in vitro models.
3.Rutin inhibits aldose reductase activit. Aldose reductase is an enzyme normally present in the eye and elsewhere in the body. It helps change glucose into the sugar alcohol sorbitol.
4.Rutin also strengthens the capillaries, and, therefore, can reduce the symptoms of haemophilia. It also may help to prevent a common, unpleasant-looking, venous edema of the legs; however, a double-blind clinical study on the effect of buckwheat tea containing rutin did not show a significant effect above placebo.
5.Rutin, as ferulic acid, can reduce the cytotoxicity of oxidized LDL cholesterol and lower the risk of heart disease.
6.There is also some evidence that rutin can be used to treat hemorrhoids, varicosis, and microangiopathy.
7.Rutin is also an antioxidant.

Pharmacokinets of Rutin

Absorption:Only about 17% of an ingested dose is absorbed
Metabolism:Hepatic

Onset of Action for Rutin

N/A

Duration of Action for Rutin

N/A

Half Life of Rutin

N/A

Side Effects of Rutin

1.Headache
2.Flushing
3.Rashes
4.Stomach upset

Contra-indications of Rutin

Rutin is contraindicated in those who are hypersensitive to any component of a rutincontaining product.

Special Precautions while taking Rutin

N/A

Pregnancy Related Information

Avoid use

Old Age Related Information

N/A

Breast Feeding Related Information

Avoid use

Children Related Information

N/A

Indications for Rutin

1.Combination,with trypsin, and bromelain for treatment of pain in osteoarhritis
2.Management of venous edema
3.To decrease capillary fragility
4.Cancer prevention

Interactions for Rutin

N/A

Typical Dosage for Rutin

For osteoarthritis: 2 tablets of a combination,which contains 100 mg of rutin, 48 mg of trypsin, and 90 mg of bromelain, 3 times daily.

Schedule of Rutin

N/A

Storage Requirements for Rutin

N/A

Effects of Missed Dosage of Rutin

N/A

Effects of Overdose of Rutin

N/A

Home Delivery for Rutin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including rutin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for rutin and other medicines and health products. Home delivery services for rutin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take rutin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for rutin before they complete the sale. You can get this information while placing the order for rutin with the pharmacy.

Rutin is a generic medicine name and there are several brands available for it. Some of the brands for rutin might be better known than rutin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have rutin in stock, you can ask for one of the branded alternatives for rutin.