Amoxycillin Pharmacology


About Amoxycillin
Semisynthetic Broad spectrum beta-lactam antibiotic, An aminopenicillin Derivative.
Mechanism of Action of Amoxycillin
Amoxycillin is a bactericidal drug. It is a Beta lactum antibiotic. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. Amoxycillin is active against gram positive and gram negative bacteria except penicillinase producing once.
Pharmacokinets of Amoxycillin
Absorption .It is well absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: In significant metabolism. Excretion: It is excreted mainly through urine and small amount excreted
in breast milk
Onset of Action for Amoxycillin
60 -120 minutes
Duration of Action for Amoxycillin
6-8 hours
Half Life of Amoxycillin
60 minutes
Side Effects of Amoxycillin
2. Vomiting
4 Nausea
10.Super infections.
Contra-indications of Amoxycillin
Hypersensitivity to Amoxicillin and other Penicillins.
Special Precautions while taking Amoxycillin
2.Lymphatic leukaemia
3.HIV infections
4.Hepatic impairment
5.Renal impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Amoxycillin
1Urinary tract infections
3 Meningitis
5.Respiratory tract infections
7.Soft tissue infections
8.Otitis media
11.Biliarytract infections
16.Chlamydia infection
17.Paratyphoid fever
18.Dental infections
Interactions for Amoxycillin
Oral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Erythromycin, Tetracycline: Reduce efficacy.
Typical Dosage for Amoxycillin
ADULT: 250 - 500 mg three to four times daily.
In severe infections dose can be increased to 3 - 6 g daily depending on the severity of infection.
CHILDREN:125 - 250 mg three to four times a day depending on the severity of infection.
Schedule of Amoxycillin
Storage Requirements for Amoxycillin
It should store at temperature below 25 degree C. Keep away from moisture and heat. Keep out of the reach of children.
Effects of Missed Dosage of Amoxycillin
Take the dose as soon as noticed and if it is the time to the next dose then skip the missed dose
Effects of Overdose of Amoxycillin
Give supportive measures and symptomatic treatment. If the patient is conscious induce emesis or gastric lavage followed by charcoal administration. Haemodialysis can be done if needed.

Home Delivery for Amoxycillin in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including amoxycillin.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for amoxycillin and other medicines and health products. Home delivery services for amoxycillin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take amoxycillin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for amoxycillin before they complete the sale. You can get this information while placing the order for amoxycillin with the pharmacy.

Amoxycillin is a generic medicine name and there are several brands available for it. Some of the brands for amoxycillin might be better known than amoxycillin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amoxycillin in stock, you can ask for one of the branded alternatives for amoxycillin.