Arformoterol tartrate Pharmacology

Arformoterol tartrate

About Arformoterol tartrate
Long acting beta-adrenoceptor agonist
Mechanism of Action of Arformoterol tartrate
Brovana is a selective beta2-adrenergic bronchodilator. Beta2-receptors are the predominant adrenergic receptors in bronchial smooth muscle. They cause stimulation of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cyclic AMP). Increased intracellular cyclic AMP levels cause relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells.
Pharmacokinets of Arformoterol tartrate
Distribution:Protein binding- 52-65%
Metabolism:Hepatic
Elimination:Renal
Onset of Action for Arformoterol tartrate
N/A
Duration of Action for Arformoterol tartrate
N/A
Half Life of Arformoterol tartrate
26 hours
Side Effects of Arformoterol tartrate
1.Congestive heart failure
2.Cardiac arrhythmias
3.Agitation Cerebral infarction
4.Somnolence
5.Tremors
6.Skin rashes
7.Skin hypertrophy
8.Skin discolouration
9.Precipitation of herpes simplex or zoster infections
10.Glaucoma
11.Cystitis
12.Glycosuria
13.Hematuria
14.Gout
15.Leg cramps
16.Osteopenia
17.Exacerbation of collagen disorders.
Contra-indications of Arformoterol tartrate
Hypersensitivity.
Special Precautions while taking Arformoterol tartrate
1.Long-acting beta-2 adrenergic agonists may increase the risk of asthma-related death
2.Renal and heaptic impairment.
3.Hepatic Function Impairment
Pregnancy Related Information
Contraindicated
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Arformoterol tartrate
Broncho spasm in chronic obstructive pulmonary disease (COPD).
Interactions for Arformoterol tartrate
1.Adrenergic drugs:Arformoterol sympathomimetic effects may be potentiated. Avoid concurrent use.
2.Beta-blockers :Effects of both agents may be inhibited. Do not normally treat patients with COPD with beta-blockers. However, under certain circumstances (eg, prophylaxis after MI), there may be no acceptable alternatives. In this instance, cardioselective beta-blockers could be considered; administer them with caution.
3.MAOIs, drugs known to prolong the QTc interval, tricyclic antidepressants:Arformoterol may potentiate these agents, increasing the risk of cardiac arrhythmias. Use with extreme caution.
4.Methylxanthines , steroids:May potentiate the hypokalemic effect of arformoterol. Monitor the clinical response and adjust treatment as needed.
5.Nonpotassium-sparing diuretics (eg, loop or thiazide diuretics) :ECG changes and/or hypokalemia may be worsened by arformoterol. Use with caution and closely monitor the clinical response.

Typical Dosage for Arformoterol tartrate
Inhalation 15 mcg twice daily (morning and evening) by nebulization (max, 30 mcg/day).
Schedule of Arformoterol tartrate
N/A
Storage Requirements for Arformoterol tartrate
Store in the protective foil pouch between 36? and 46?F. Protect from light and excessive heat.
Effects of Missed Dosage of Arformoterol tartrate
N/A
Effects of Overdose of Arformoterol tartrate
Contact immediate medical attention
Signs and symptoms may include angina, hypertension or hypotension, tachycardia, with rates up to 200 beats/min, arrhythmias, nervousness, headache, tremor, dry mouth, palpitation, muscle cramps, nausea, dizziness, fatigue, malaise, hypokalemia, hyperglycemia, metabolic acidosis and insomnia. As with all inhaled sympathomimetic medications, cardiac arrest and even death may be associated with an overdose.

Home Delivery for Arformoterol tartrate in Your City

Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including arformoterol tartrate.

However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for arformoterol tartrate and other medicines and health products. Home delivery services for arformoterol tartrate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take arformoterol tartrate only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for arformoterol tartrate before they complete the sale. You can get this information while placing the order for arformoterol tartrate with the pharmacy.

Arformoterol tartrate is a generic medicine name and there are several brands available for it. Some of the brands for arformoterol tartrate might be better known than arformoterol tartrate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have arformoterol tartrate in stock, you can ask for one of the branded alternatives for arformoterol tartrate.