Mometasone + Fusidic Acid Pharmacology

Mometasone + Fusidic Acid

About Mometasone + Fusidic Acid
N/A
Mechanism of Action of Mometasone + Fusidic Acid
N/A
Pharmacokinets of Mometasone + Fusidic Acid
N/A
Onset of Action for Mometasone + Fusidic Acid
N/A
Duration of Action for Mometasone + Fusidic Acid
N/A
Half Life of Mometasone + Fusidic Acid
N/A
Side Effects of Mometasone + Fusidic Acid
N/A
Contra-indications of Mometasone + Fusidic Acid
N/A
Special Precautions while taking Mometasone + Fusidic Acid
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution;Continuous treatment not recommended
Indications for Mometasone + Fusidic Acid
Treatment of eczematous dermatoses including atopic eczema, infantile eczema, discoid eczema, stasis eczema, contact eczema and seborrhoeic eczema when secondary bacterial infection is confirmed or suspected.
Interactions for Mometasone + Fusidic Acid
N/A
Typical Dosage for Mometasone + Fusidic Acid
N/A
Schedule of Mometasone + Fusidic Acid
N/A
Storage Requirements for Mometasone + Fusidic Acid
N/A
Effects of Missed Dosage of Mometasone + Fusidic Acid
N/A
Effects of Overdose of Mometasone + Fusidic Acid
N/A

Mometasone

About Mometasone
A glucocorticoid steroid, Anti psoriatic,anti asthma ,anti inflammatory.
Mechanism of Action of Mometasone
Mometasone is a topical medium potency glucocorticoid. The drug exerts its pharmacological action by penetrating and binding to cytoplasmic receptor protein and causes a structural change in steroid receptor complex. This structural change allows it`s migration in to the nucleus and then binding to specific sites on the DNA which leads to transcription of specific m-RNA and which ultimately regulates protein synthesis. It exerts highly selective glucocorticoid action. It stimulates the enzymes needed to decrease the inflammatory response.
The drug exerts anti-inflammatory and immunosuppressant actions as follows: - 1) Induce lipocortins in macrophages, endothelium, and fibroblasts which inhibits Phospholipase A2 and thus decreases the production of Prostaglandins, leukotrienes (LT), and platelet activating factor, 2) Causes negative regulation of genes for cytokines in macrophages, endothelial cells and lymphocytes and thus decreases the production of interleukins (IL-1, IL-2, IL-3, IL-6), TNF-a, GM-CSF (granulocyte macrophage colony stimulating factor), Gama interferon and suppresses fibroblast proliferation and T-lymphocyte functions and interferes chemo taxis. 3) Decreases the production of acute phase reactants from macrophages and endothelial cells and interferes complement function. 4) Decreases the production of ELAM-1(Endothelial leukocyte adhesion molecule-1) and ICAM-1(intracellular adhesion molecule-1) in endothelial cells. 5) Inhibit IgE mediated histamine and LT-C4 release from basophiles and the effects of antigen-antibody reaction is not mediated 6) Reduces the production of collagenase and stromolysin and thus prevents tissue destruction.
Pharmacokinets of Mometasone
Absorption: Mometasone is absorbed through intact skin after topical administration and the amount absorbed is depending on the type of inflammation, vehicle used, area of skin and the epidermal barrier. Absorption is increased in inflammation, occlusion and skin damage.
Onset of Action for Mometasone
N/A
Duration of Action for Mometasone
N/A
Half Life of Mometasone
N/A
Side Effects of Mometasone
1.Thinning of epidermis
2.Burning
3.Itching
4.Irritation
5.Atrophy (Dermal changes)
6.Telangiectasia
7.Striae
8.Hypopigmentation
9.Contact dermatitis
10.Perioral dermatitis
11.Cataract, Glaucoma, Corneal ulcers caused by application around eyelids and surrounding skin
12.Dry skin
13.Stinging
14.Tingling
Contra-indications of Mometasone
1.Hypersensitivity to Mometasone and other corticosteroids
2.Acne vulgaris
3.Acne Rosacea
5.Tuberculosis infection of the skin
6.Viral, fungal or bacterial primary infections
7.Ulcers
Special Precautions while taking Mometasone
1.Avoid the use of medicament if irritation or hypersensitivity occurs
2.Prolonged use
3.Psoriasis
4.Avoid contact with eyes
5.Avoid occlusive dressing
6.Not used more than 5 days on the face or in the children
7.Withdraw gradually after prolonged use
8.Use caution on areas where the skin creases, such as armpits, knees, and elbows
9.Avoid application on large surface area
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: contraindicated
Indications for Mometasone
1.Otitis externa
2 Eczema
3.Dermatoses (secondary infected)
4.Psoriasis
5.Neuro dermatitis
6.Intertrigo
7.Lichen planus
8.Anal and vulval pruritis
Interactions for Mometasone
N/A
Typical Dosage for Mometasone
Topical: Mometasone Furoate 0.1 % cream, ointment or lotion is used.
Clean the affected area and wash with warm water and then dry. Apply 2 - 3 times daily for 2 weeks with gentle massage.

Schedule of Mometasone
H
Storage Requirements for Mometasone
Store at room temperature. Protect from heat and light. Keep the container tightly closed. Keep out of the reach of children
Effects of Missed Dosage of Mometasone
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Mometasone
Give supportive measures and symptomatic treatment.

Fusidic acid

About Fusidic acid
A bacteriostatic Steroid Antibiotic, Systemic antibacterial, anti-infective.
Mechanism of Action of Fusidic acid
Fusidic acid is a bactericidal or bacteriostatic drug depending upon the concentration. It inhibits the transfer of aminoacid from aminoacyl sRNA to the protein. This will leads to inhibition of protein synthesis in the bacteria and prevent the growth of microbes.
Pharmacokinets of Fusidic acid
Absorption: It is very poorly absorbed after topical administration.
Onset of Action for Fusidic acid
NULL.
Duration of Action for Fusidic acid
NULL.
Half Life of Fusidic acid
N/A
Side Effects of Fusidic acid
1. Contact dermatitis
2. Irritation
3. Burning
4. Redness
5. Swelling
6. Rashes
Contra-indications of Fusidic acid
1. Hypersensitivity to Fusidic acid
Special Precautions while taking Fusidic acid
1. Avoid contact with eyes
2. If irritation occurs discard the use of medicament
3. Hepatic impairment
4. Monitor liver function test
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Contraindicated
Children Related Information
Use with caution
Indications for Fusidic acid
Primary and secondary skin infections
1. Impetigo
2. Erythrasma
3. Folliculitis
4. Sycosis barbae
5. Hidradenitis
Interactions for Fusidic acid
NULL.
Typical Dosage for Fusidic acid
Fusidic acid 2% cream or ointment .Clean and dry the affected area. Apply the drug as thin layer.2 - 4 times daily.
Schedule of Fusidic acid
N/A
Storage Requirements for Fusidic acid
Store in a cool dry place. Protect from heat and light. Keep out of the reach of children
Effects of Missed Dosage of Fusidic acid
Apply the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Fusidic acid
Give supportive measures and symptomatic treatment.

Home Delivery for Mometasone + Fusidic Acid in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for mometasone + fusidic acid and other medicines and health products. Home delivery services for mometasone + fusidic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take mometasone + fusidic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for mometasone + fusidic acid before they complete the sale. You can get this information while placing the order for mometasone + fusidic acid with the pharmacy.

Mometasone + Fusidic Acid is a generic medicine name and there are several brands available for it. Some of the brands for mometasone + fusidic acid might be better known than mometasone + fusidic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have mometasone + fusidic acid in stock, you can ask for one of the branded alternatives for mometasone + fusidic acid.