Biotin + Folic Acid Pharmacology

Biotin + Folic Acid

About Biotin + Folic Acid
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Mechanism of Action of Biotin + Folic Acid
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Pharmacokinets of Biotin + Folic Acid
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Onset of Action for Biotin + Folic Acid
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Duration of Action for Biotin + Folic Acid
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Half Life of Biotin + Folic Acid
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Side Effects of Biotin + Folic Acid
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Contra-indications of Biotin + Folic Acid
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Special Precautions while taking Biotin + Folic Acid
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Pregnancy Related Information
May be used
Old Age Related Information
N/A
Breast Feeding Related Information
May be used
Children Related Information
N/A
Indications for Biotin + Folic Acid
As a dietary supplement
Interactions for Biotin + Folic Acid
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Typical Dosage for Biotin + Folic Acid
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Schedule of Biotin + Folic Acid
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Storage Requirements for Biotin + Folic Acid
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Effects of Missed Dosage of Biotin + Folic Acid
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Effects of Overdose of Biotin + Folic Acid
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Biotin

About Biotin
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Mechanism of Action of Biotin
Biotin excerts it`s pharmacological action by influencing metabolic reactions. It acts as a coenzyme for carbohydrate, fat, and protein metabolism. It is required for cell growth and production of fatty acids. It is required for healthy maintenance of hair, skin, sweat glands, nerve tissue, and bone marrow. It also helps in the transfer of carbon dioxide and in the maintenance of a steady blood sugar level.
Pharmacokinets of Biotin
Absorption: Well absorbed orally, Excretion: Extra drug is excreted unchanged in urine.
Onset of Action for Biotin
N/A
Duration of Action for Biotin
N/A
Half Life of Biotin
N/A
Side Effects of Biotin
N/A
Contra-indications of Biotin
Hypersensitivity of any biotin products.
Special Precautions while taking Biotin
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Biotin
1.Biotin deficiency
2 Alopecia
3.Brittle nails
4.Prevent diabetic neuropathy and lower blood glucose levels in diabetic patients
5.Seborrheic dermatitis
6.Dry skin.
Interactions for Biotin
N/A
Typical Dosage for Biotin
Oral: 30 to 70mcg daily. Increased up to 300mcg/day if required based on the severity of deficiency.
Pregnancy: 30mcg daily
Lactation: 35mcg daily
Prevent brittle nails: 2.5mg/day.
Schedule of Biotin
C1
Storage Requirements for Biotin
Store in a cool dry area in a well closed container. Protects from moisture, light and direct heat.
Effects of Missed Dosage of Biotin
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Biotin
Provide symptomatic treatment and supportive measures.

Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
N/A
Side Effects of Folic Acid
N/A
Contra-indications of Folic Acid
N/A
Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Home Delivery for Biotin + Folic Acid in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for biotin + folic acid and other medicines and health products. Home delivery services for biotin + folic acid may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take biotin + folic acid only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for biotin + folic acid before they complete the sale. You can get this information while placing the order for biotin + folic acid with the pharmacy.

Biotin + Folic Acid is a generic medicine name and there are several brands available for it. Some of the brands for biotin + folic acid might be better known than biotin + folic acid itself. If the pharmacy that's willing to deliver medicines to your home doesn't have biotin + folic acid in stock, you can ask for one of the branded alternatives for biotin + folic acid.