Gatifloxacin + Prednisolone (Eye preparation) Pharmacology

Gatifloxacin + Prednisolone (Eye preparation)

About Gatifloxacin + Prednisolone (Eye preparation)

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Mechanism of Action of Gatifloxacin + Prednisolone (Eye preparation)

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Pharmacokinets of Gatifloxacin + Prednisolone (Eye preparation)

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Onset of Action for Gatifloxacin + Prednisolone (Eye preparation)

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Duration of Action for Gatifloxacin + Prednisolone (Eye preparation)

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Half Life of Gatifloxacin + Prednisolone (Eye preparation)

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Side Effects of Gatifloxacin + Prednisolone (Eye preparation)

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Contra-indications of Gatifloxacin + Prednisolone (Eye preparation)

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Special Precautions while taking Gatifloxacin + Prednisolone (Eye preparation)

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Pregnancy Related Information

Contraindicated

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Contraindicated

Indications for Gatifloxacin + Prednisolone (Eye preparation)

Indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists.

Interactions for Gatifloxacin + Prednisolone (Eye preparation)

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Typical Dosage for Gatifloxacin + Prednisolone (Eye preparation)

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Schedule of Gatifloxacin + Prednisolone (Eye preparation)

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Storage Requirements for Gatifloxacin + Prednisolone (Eye preparation)

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Effects of Missed Dosage of Gatifloxacin + Prednisolone (Eye preparation)

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Effects of Overdose of Gatifloxacin + Prednisolone (Eye preparation)

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Gatifloxacin

About Gatifloxacin

Fourth-generation fluoroquinolone, DNA Gyrase Inhibitor,Topoisomerase I Inhibitor, Antibiotic.

Mechanism of Action of Gatifloxacin

Gatifloxacin acts by inhibiting the enzyme DNA gyrase (Topoisomerase 2) and Topoisomerase 4.DNA gyrase helps in the formation of a highly condensed three dimensional structure of the DNA by its nicking and closing activity and also by introducing negative supercoil in to the DNA double helix. Gatifloxacin inhibits DNA gyrase which results in abnormal linkage between opened DNA and gyrase and negative supercoiling is impaired. This will inhibits transcription of DNA in to RNA and subsequent protein synthesis in microorganisms.

Pharmacokinets of Gatifloxacin

Absorption: Gatifloxacin is well absorbed after oral administration. Distribution: It is distributed widely in the body. Metabolism: It undergoes limited metabolism. Excretion: Drug is excreted mainly through urine.

Onset of Action for Gatifloxacin

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Duration of Action for Gatifloxacin

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Half Life of Gatifloxacin

8 hour

Side Effects of Gatifloxacin

1.Nausea
2.Vomiting
3.Diarrhoea
4.Abdominal discomfort
5.Vaginitis
6.Dizziness
7.Headache

Contra-indications of Gatifloxacin

Hypersensitivity to Gatifloxacin and other Fluoroquinolones

Special Precautions while taking Gatifloxacin

1.Hepatic impairment
2.Renal impairment
3.Epilepsy
4.Concomitant use of antiarrhythmic drugs
5.Caution while driving the vehicle or operating machine or involved in any hazardous activities.
6.Avoid long exposure to sunlight.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Contraindicated

Children Related Information

Contraindicated
NEONATES: contraindicated

Indications for Gatifloxacin

1.Pneumonia
2.Bronchitis
3.Sinusitis
4.Urinary tract infections
5.Pyelonephritis
6.Skin and skin structure infections
7.Gonorrhoea.

Interactions for Gatifloxacin

Probenicid : Systemic exposure to gatifloxacin is increased following concomitant administration of gatifloxacin and probenicid.
Ferrous sulphate /Antacid : Systemic exposure is reduced when gatifloxacin is given concomitantly with Ferrous sulphate or with antacids containing aluminium or magnesium salts.

Typical Dosage for Gatifloxacin

Adults: 400 mg once daily for 1 - 2 week
Dose is determined on the basis of severity of the infection and type of infecting organism
Bronchitis: 400 mg once daily for 5 days
Sinusitis: 400 mg once daily for 10 days
Pneumonia: 400 mg once daily for 1 - 2 week
Skin and skin structure infections, Complicated UTI, Pyelonephritis: 400 mg once daily for 7 - 10 days
Uncomplicated UTI: 200 mg / day for 3 days
Gonorrhoea: 400 mg as a single dose.

Schedule of Gatifloxacin

Storage Requirements for Gatifloxacin

Store at room temperature in a tightly closed container.

Effects of Missed Dosage of Gatifloxacin

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose.

Effects of Overdose of Gatifloxacin

Give supportive measures and symptomatic treatment.

About

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Home Delivery for Gatifloxacin + Prednisolone (Eye preparation) in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for gatifloxacin + prednisolone (eye preparation) and other medicines and health products. Home delivery services for gatifloxacin + prednisolone (eye preparation) may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

Please be aware that you should take gatifloxacin + prednisolone (eye preparation) only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for gatifloxacin + prednisolone (eye preparation) before they complete the sale. You can get this information while placing the order for gatifloxacin + prednisolone (eye preparation) with the pharmacy.

Gatifloxacin + Prednisolone (Eye preparation) is a generic medicine name and there are several brands available for it. Some of the brands for gatifloxacin + prednisolone (eye preparation) might be better known than gatifloxacin + prednisolone (eye preparation) itself. If the pharmacy that's willing to deliver medicines to your home doesn't have gatifloxacin + prednisolone (eye preparation) in stock, you can ask for one of the branded alternatives for gatifloxacin + prednisolone (eye preparation).