Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone Pharmacology

Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

About Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Mechanism of Action of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Pharmacokinets of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Onset of Action for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Duration of Action for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Half Life of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Side Effects of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Contra-indications of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Special Precautions while taking Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

1.Acidity
2.Indigestion
3.Heart Burn
4.Flatulence

Interactions for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Typical Dosage for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Schedule of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Storage Requirements for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Effects of Missed Dosage of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Effects of Overdose of Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone

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Calcium

About Calcium

Calcium is necessary for cardiac function, muscle contraction, nervous activity, coagulation of blood and for maintaining structural integrity of cell membranes.
Plasma concentration of calcium is kept in normal range by three endocrine factors which control metabolism of calcium. These are (a) Parathyroid hormone, (b) Calcitonin, (c) Vitamin D. Calcium in plasma is bound to albumin, is complexed with anions (e.g. phosphate) and as diffusible ionic calcium. The physiological effects are exerted by ionic calcium. The predominant source of calcium is dairy products and the daily intake varies from 200 - 2500 mg. Adequate calcium intake is particularly important during periods of bone growth in childhood and adolescence and during pregnancy and lactation.
Patients with advanced renal insufficiency exhibit phosphate retention and some degree of hyperphosphataemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy and soft tissue calcification. Calcium acetate, when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the faeces.
Deficiency signs and symptoms: Osteoporosis, pathological fractures, brittle nails and hair.

Mechanism of Action of Calcium

Calcium is essential for maintaining the functional integrity of nervous, muscular, and skeletal system. It controls excitability of nerves and muscles and regulates permeability of cell membrane. It also regulates cell adhesion and maintains integrity of cell membrane. Calcium acts as intracellular messenger for hormones, autacoids, and transmitters. It is required for excitation-contraction coupling in all types of muscle and excitation-secretion coupling in exocrine and endocrine glands. It is essential for release of transmitters from nerve endings and other release reactions. It is also essential for impulse generation in heart and determines level of automaticity and
A-V conduction. Calcium is also required for blood-coagulation.

Pharmacokinets of Calcium

Absorption: Actively absorbed from gastrointestinal tract in an ionized form; and vitamin D in it`s active form is required for calcium absorption, Distribution: Distributed mainly in to skeletal tissue (99%) and 1% is distributed equally between the intracellular and extra cellular fluid. CSF levels are about half of the serum calcium levels, Metabolism: Not significantly metabolized in the body, Excretion: Excreted mainly through faeces and a small amount is excreted through urine.

Onset of Action for Calcium

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Duration of Action for Calcium

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Half Life of Calcium

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Side Effects of Calcium

1.Constipation
2.Bloating
3.Excess gas
4.Anorexia
5.Nausea
6.Vomiting
7.Abdominal pain
8.Thirst
9.Hypercalcaemia
10.Polyuria
11.Dry mouth
12.Delirium
13.Confusion

Contra-indications of Calcium

1.Renal calculi
2.Hypophosphataemia
3.Hypercalcaemia
4.Ventricular fibrillation.

Special Precautions while taking Calcium

1.Renal impairment
2.Cardiac diseases
3.Sarcoidosis
4.Cor pulmonale
5.Respiratory acidosis
6.Respiratory failure
7.End stage renal failure
8.Hypoparathyroid patients
9.Digitalized patients
10.Prolonged use of therapeutic amounts.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

May be used

Children Related Information

Use with caution

Indications for Calcium

1.Hypocalcaemia
2.Calcium and vitamin D deficiency
3.Calcium deficiency during pregnancy and lactation
4.Rickets
5.Prevention of osteoporosis in postmenopausal women
6.Chronic renal failure.

Interactions for Calcium

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Typical Dosage for Calcium

Oral: 500mg to 2g daily in two to four divided doses.
Hypocalcaemia:
Adults: 1g daily. Increases to 2g daily if required.
Prevention of osteoporosis: 1 to 1.5g daily.
Children: 45 to 65mg/kg daily.
Neonates: 50 to 150mg/kg and should not exceed 1g.

Schedule of Calcium

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Storage Requirements for Calcium

Store in a well closed container in a cool and dry place. Protect from light.

Effects of Missed Dosage of Calcium

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Calcium

Remove calcium from stomach by induced emesis and gastric lavage. Provide symptomatic treatment and supportive measures.

Magnesium Trisilicate

About Magnesium Trisilicate

Mineral, Magnesium compound, Antacid.

Mechanism of Action of Magnesium Trisilicate

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Pharmacokinets of Magnesium Trisilicate

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Onset of Action for Magnesium Trisilicate

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Duration of Action for Magnesium Trisilicate

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Half Life of Magnesium Trisilicate

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Side Effects of Magnesium Trisilicate

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Contra-indications of Magnesium Trisilicate

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Special Precautions while taking Magnesium Trisilicate

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Pregnancy Related Information

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Old Age Related Information

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Breast Feeding Related Information

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Children Related Information

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Indications for Magnesium Trisilicate

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Interactions for Magnesium Trisilicate

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Typical Dosage for Magnesium Trisilicate

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Schedule of Magnesium Trisilicate

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Storage Requirements for Magnesium Trisilicate

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Effects of Missed Dosage of Magnesium Trisilicate

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Effects of Overdose of Magnesium Trisilicate

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Magnesium Hydroxide

About Magnesium Hydroxide

Mineral, Magnesium compound, Antacid and laxative.

Mechanism of Action of Magnesium Hydroxide

It neutralize the gastric acid (where the hydroxide ions from the Mg(OH)2 combine with acidic H+ ions produced in the form of hydrochloric acid by parietal cells in the stomach). This relieves the hyperacidity problems in the stomach.

Pharmacokinets of Magnesium Hydroxide

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Onset of Action for Magnesium Hydroxide

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Duration of Action for Magnesium Hydroxide

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Half Life of Magnesium Hydroxide

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Side Effects of Magnesium Hydroxide

1. Stomach cramps
2. Upset stomach
3. Vomiting
4. Diarrhea
5. Black/tarry stools
6. Rectal bleeding.
7. Constipation
8. Loss of appetite
9. Unusual tiredness
10. Muscle weakness
11. Hypermagnesaemia
12. Renal failure

Contra-indications of Magnesium Hydroxide

1. Hypersensitivity to the drug
2. Kidney disease
3. Stomach/abdominal pain
4. Nausea
5. Vomiting

Special Precautions while taking Magnesium Hydroxide

1. Colostomy
2. Dehydration
3. Diarrhea
4. Intestinal problems like colitis
5.Do not take any other medication within 1 to 2 hours of taking this medication.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Less than 6 Years : Contraindicated

Indications for Magnesium Hydroxide

1. Constipation
2. Peptic ulcer
3. Hiatal hernia

Interactions for Magnesium Hydroxide

N/A

Typical Dosage for Magnesium Hydroxide

Oral-
Adult-
Antacid:
Tab-500mg to 1.5g daily.
Liquid-5-15ml daily.
Laxative:
Tab-2.4-4.8g daily.
Liquid -30-60ml daily.

Schedule of Magnesium Hydroxide

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Storage Requirements for Magnesium Hydroxide

Store it at room temperature (15-30 degree C) and away from excess heat and moisture.

Effects of Missed Dosage of Magnesium Hydroxide

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Magnesium Hydroxide

Give symptomatic and supportive treatment.

Simethicone

About Simethicone

Oral anti-foaming agent, Silicones, Antiflatulent.

Mechanism of Action of Simethicone

This anti-gas (anti-flatulence) medication acts in the stomach and intestines to change the surface tension of gas bubbles, enabling smaller bubbles to join together into bigger bubbles. It results elimination of gas more easily by belching or passing flatus.

Pharmacokinets of Simethicone

Excretion- Excreted through feces.

Onset of Action for Simethicone

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Duration of Action for Simethicone

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Half Life of Simethicone

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Side Effects of Simethicone

1. Bloating
2. Constipation
3. Diarrhea
4. Gas
5. Heartburn

Contra-indications of Simethicone

1. Hypersensitivity to the drug
2. Liver disease
3. Kidney disease
4. Serious illness

Special Precautions while taking Simethicone

1.Swallow the tablets and capsules with a full glass of water.
2.Chew the chewable tablets thoroughly before swallowing.
3.Shake the drops well before using them.
4.To make administration easier, the drops can be mixed with 30 ml (2 tablespoons) of water or another liquid.

Pregnancy Related Information

Use with caution

Old Age Related Information

Use with caution

Breast Feeding Related Information

Use with caution

Children Related Information

Use with caution

Indications for Simethicone

1. Abdominal pain which is due to excessive gas in the digestive tract
2. Before gastroscopy or radiography of the bowel

Interactions for Simethicone

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Typical Dosage for Simethicone

Oral-
Adults and teenagers-
60 -125mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.
Chewable tablets:
Adults and teenagers-
40 -125 mg four times a day, after meals and at bedtime or 150 mg three times a day, after meals. Not more than 500 mg should be taken in twenty-four hours.
Suspension:
Adults and teenagers-
40 -95 mg four times a day, after meals and at bedtime. Not more than 500 mg should be taken in twenty-four hours.

Schedule of Simethicone

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Storage Requirements for Simethicone

Stored at room temperature (15-30?C) away from moisture and heat.

Effects of Missed Dosage of Simethicone

Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.

Effects of Overdose of Simethicone

Give symptomatic and supportive treatment.

Home Delivery for Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone in Your City

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Calcium + Magnesium Trisilicate + Magnesium Hydroxide + Simethicone is a generic medicine name and there are several brands available for it. Some of the brands for calcium + magnesium trisilicate + magnesium hydroxide + simethicone might be better known than calcium + magnesium trisilicate + magnesium hydroxide + simethicone itself. If the pharmacy that's willing to deliver medicines to your home doesn't have calcium + magnesium trisilicate + magnesium hydroxide + simethicone in stock, you can ask for one of the branded alternatives for calcium + magnesium trisilicate + magnesium hydroxide + simethicone.