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- Pharmacology For Amoxycillin + Cloxacillin + Lactobacillus
Amoxycillin + Cloxacillin + Lactobacillus Pharmacology
Amoxycillin + Cloxacillin + Lactobacillus
About Amoxycillin + Cloxacillin + LactobacillusN/AMechanism of Action of Amoxycillin + Cloxacillin + LactobacillusN/APharmacokinets of Amoxycillin + Cloxacillin + LactobacillusN/AOnset of Action for Amoxycillin + Cloxacillin + LactobacillusN/ADuration of Action for Amoxycillin + Cloxacillin + LactobacillusN/AHalf Life of Amoxycillin + Cloxacillin + LactobacillusN/ASide Effects of Amoxycillin + Cloxacillin + LactobacillusN/AContra-indications of Amoxycillin + Cloxacillin + LactobacillusN/ASpecial Precautions while taking Amoxycillin + Cloxacillin + LactobacillusN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Amoxycillin + Cloxacillin + LactobacillusN/AInteractions for Amoxycillin + Cloxacillin + LactobacillusN/ATypical Dosage for Amoxycillin + Cloxacillin + LactobacillusN/ASchedule of Amoxycillin + Cloxacillin + LactobacillusN/AStorage Requirements for Amoxycillin + Cloxacillin + LactobacillusN/AEffects of Missed Dosage of Amoxycillin + Cloxacillin + LactobacillusN/AEffects of Overdose of Amoxycillin + Cloxacillin + LactobacillusN/AAmoxycillin
About AmoxycillinSemisynthetic Broad spectrum beta-lactam antibiotic, An aminopenicillin Derivative.Mechanism of Action of AmoxycillinAmoxycillin is a bactericidal drug. It is a Beta lactum antibiotic. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. Amoxycillin is active against gram positive and gram negative bacteria except penicillinase producing once.Pharmacokinets of AmoxycillinAbsorption .It is well absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: In significant metabolism. Excretion: It is excreted mainly through urine and small amount excreted
in breast milk
Onset of Action for Amoxycillin60 -120 minutesDuration of Action for Amoxycillin6-8 hoursHalf Life of Amoxycillin60 minutesSide Effects of Amoxycillin1.Aaphylaxis
2. Vomiting
3.Diarrhoea
4 Nausea
5.Rash
6.Urticaria
7.Thrombocytopenia
8.Nephritis
9.Seizure
10.Super infections.
Contra-indications of AmoxycillinHypersensitivity to Amoxicillin and other Penicillins.Special Precautions while taking Amoxycillin1.Mononucleosis
2.Lymphatic leukaemia
3.HIV infections
4.Hepatic impairment
5.Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Amoxycillin1Urinary tract infections
2.Gonorrhoea
3 Meningitis
4.SABE
5.Respiratory tract infections
6.Septicemia
7.Soft tissue infections
8.Otitis media
9.Sinusitis
10.Tetanus
11.Biliarytract infections
12.Bronchitis
13.Salmonellosis
14.Typhoid
15.Gastroenteritis
16.Chlamydia infection
17.Paratyphoid fever
18.Dental infections
Interactions for AmoxycillinOral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Erythromycin, Tetracycline: Reduce efficacy.Typical Dosage for AmoxycillinADULT: 250 - 500 mg three to four times daily.
In severe infections dose can be increased to 3 - 6 g daily depending on the severity of infection.
CHILDREN:125 - 250 mg three to four times a day depending on the severity of infection.
Schedule of AmoxycillinHStorage Requirements for AmoxycillinIt should store at temperature below 25 degree C. Keep away from moisture and heat. Keep out of the reach of children.Effects of Missed Dosage of AmoxycillinTake the dose as soon as noticed and if it is the time to the next dose then skip the missed doseEffects of Overdose of AmoxycillinGive supportive measures and symptomatic treatment. If the patient is conscious induce emesis or gastric lavage followed by charcoal administration. Haemodialysis can be done if needed.
Cloxacillin
About CloxacillinIt is a Penicillinase resistant Penicillin, Penicillin derived antibiotic.Mechanism of Action of CloxacillinCloxacillin is a bactericidal drug. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. In addition to this it is not degraded by penicillinase enzyme and therefore it can be useful against penicillinase producing bacteria also.Pharmacokinets of CloxacillinAbsorption .It is readily absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: It does not undergo metabolism. Excretion: It is excreted mainly through urine and small amount excreted through breast milk.Onset of Action for Cloxacillin30-60 minutesDuration of Action for CloxacillinAbout 6 hoursHalf Life of Cloxacillin30 minutesSide Effects of Cloxacillin1.Anaphylaxis
2.Rash
3.Urticaria
4.Thrombocytopenia
5.Seizure
Contra-indications of CloxacillinHypersensitive to Cloxacillin or other Penicillins.Special Precautions while taking Cloxacillin1.Heart failure
2.Uremia
3.Hypokalemia
4 Bleeding tendencies
5.Meningitis
6.Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationN/AIndications for Cloxacillin1.Urinary tract infections
2.Respiratory tract infections
3.Septicaemia
4.Osteomyelitis
5.Endocarditis
6.Pneumonia
7.Sinusitis
8.Bronchiectasis
Interactions for CloxacillinOral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Atenolol: Bio-availability of atenolol reduced.
Allopurinol: Increases risk of cloxacillin induced skin rash.
Probenecid: Increases blood levels.
Erythromycin & Tetracyclines: Reduce efficacy.
Clavulanic Acid: Synergy.
Food: Interferes with absorptionTypical Dosage for CloxacillinADULT
1 - 2 g daily in four divided dose depending on the severity of infection
CHILDREN
50 - 100 mg/kg/day in four divided dose depending on the severity of infection
Schedule of CloxacillinHStorage Requirements for CloxacillinThe vial should be stored in room temperature away from heat and moisture. Keep out of the reach of childrenEffects of Missed Dosage of CloxacillinTake the dose as soon as noticed and if it is the time to the next dose then skip the missed doseEffects of Overdose of CloxacillinGive supportive measures and symptomatic treatment. Absorption of drug can be reduced by gastric lavage or induction of emesisLactobacillus
About LactobacillusLactic acid bacteria, Probiotic,Antidiarrhoeal.Mechanism of Action of LactobacillusLactobacillus is a probiotic and it is called as friendly bacteria. It is used along with antibiotic in order to restore the body`s natural microbial flora with in the digestive tract. Lactobacillus helps in the breakdown of food and leads to the production of lactic acid, hydrogen peroxide and other byproducts. This will alter the intestinal pH and that make the environment hostile for pathogens.Pharmacokinets of LactobacillusAbsorption: It is orally well absorbed after oral administration.
Onset of Action for LactobacillusN/ADuration of Action for LactobacillusN/AHalf Life of LactobacillusN/ASide Effects of Lactobacillus1.Abdominal discomfort
2.Vaginal irritation (when used vaginally)
Contra-indications of Lactobacillus1.Recent bowel surgery
2.Intestinal damage
3.Weakened immune system
Special Precautions while taking LactobacillusPatient on Inulin treatmentPregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with caution
NEONATES: Use with cautionIndications for Lactobacillus1.Aphthous stomatitis
2.Hypochlorhydria
3.Hepatic encephalopathy
4.Adjuvant to antibiotic therapy
5.Diarrhoea.Interactions for LactobacillusN/ATypical Dosage for LactobacillusAdult: 60 - 150 million spores 3 times daily depending on the severity of infections.
Vaginal bacterial infections: 1- 2 billion bacteria 2 - 3 times daily
Suppositories:
Vaginal infections, cystitis: 1 - 2 suppositories are inserted in to vagina at night for 2 weeks. Each suppository contains 1 - 2 billion lactobacilli
Schedule of LactobacillusN/AStorage Requirements for LactobacillusRefrigerate below 5 degree C.Effects of Missed Dosage of LactobacillusN/AEffects of Overdose of LactobacillusGive supportive measures and symptomatic treatmentHome Delivery for Amoxycillin + Cloxacillin + Lactobacillus in Your City
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Amoxycillin + Cloxacillin + Lactobacillus is a generic medicine name and there are several brands available for it. Some of the brands for amoxycillin + cloxacillin + lactobacillus might be better known than amoxycillin + cloxacillin + lactobacillus itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amoxycillin + cloxacillin + lactobacillus in stock, you can ask for one of the branded alternatives for amoxycillin + cloxacillin + lactobacillus.
