Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium Pharmacology

Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium

About Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Mechanism of Action of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
Methylcobalamin is an essential nutrient for neurons and Alpha Lipoic Acid is a powerful antioxidant that protects the neurons from oxidative stress.
Pharmacokinets of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Onset of Action for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Duration of Action for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Half Life of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Side Effects of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Contra-indications of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Special Precautions while taking Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
Useful in various Neuropathies like Diabetic Neuropathy, Alcoholic Neuropathy, Drug-induced Neuropathy, Bell's Palsy, Trigeminal Neuralgia, Sciatica, Post-herpetic Neuralgia and Optic Neuritis.
Interactions for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Typical Dosage for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Schedule of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Storage Requirements for Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Effects of Missed Dosage of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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Effects of Overdose of Mecobalamine + Alpha Lipoic Acid + Chromium + Selenium
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About
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Mechanism of Action of
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Special Precautions while taking
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Indications for
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Effects of Missed Dosage of
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Effects of Overdose of
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About
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Special Precautions while taking
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Chromium

About Chromium
Chromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.

Mechanism of Action of Chromium
Chromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.
Pharmacokinets of Chromium
Absorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.
Onset of Action for Chromium
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Duration of Action for Chromium
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Half Life of Chromium
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Side Effects of Chromium
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Contra-indications of Chromium
1. Hypersensitivity to the drug.
Special Precautions while taking Chromium
1. Prolonged therapy with the drug
2.Hypoglycaemia
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
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Indications for Chromium
1.Type I diabetes mellitus
2.Type II diabetes mellitus
3.Obesity.
Interactions for Chromium
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Typical Dosage for Chromium
Oral: 200 mcg daily; increases up to 1mg daily if required.
Schedule of Chromium
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Storage Requirements for Chromium
Store in a well closed container at a cool dry place.
Effects of Missed Dosage of Chromium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Chromium
Give supportive measures and symptomatic treatment.

Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
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Duration of Action for Selenium
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Half Life of Selenium
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Side Effects of Selenium
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Contra-indications of Selenium
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Special Precautions while taking Selenium
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Indications for Selenium
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Interactions for Selenium
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Typical Dosage for Selenium
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Schedule of Selenium
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Storage Requirements for Selenium
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Effects of Missed Dosage of Selenium
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Effects of Overdose of Selenium
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