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- Pharmacology For Amoxycillin + Serratiopeptidase
Amoxycillin + Serratiopeptidase Pharmacology
Amoxycillin + Serratiopeptidase
About Amoxycillin + SerratiopeptidaseN/AMechanism of Action of Amoxycillin + SerratiopeptidaseN/APharmacokinets of Amoxycillin + SerratiopeptidaseN/AOnset of Action for Amoxycillin + SerratiopeptidaseN/ADuration of Action for Amoxycillin + SerratiopeptidaseN/AHalf Life of Amoxycillin + SerratiopeptidaseN/ASide Effects of Amoxycillin + SerratiopeptidaseN/AContra-indications of Amoxycillin + SerratiopeptidaseN/ASpecial Precautions while taking Amoxycillin + SerratiopeptidaseN/APregnancy Related InformationN/AOld Age Related InformationN/ABreast Feeding Related InformationN/AChildren Related InformationN/AIndications for Amoxycillin + SerratiopeptidaseN/AInteractions for Amoxycillin + SerratiopeptidaseN/ATypical Dosage for Amoxycillin + SerratiopeptidaseN/ASchedule of Amoxycillin + SerratiopeptidaseN/AStorage Requirements for Amoxycillin + SerratiopeptidaseN/AEffects of Missed Dosage of Amoxycillin + SerratiopeptidaseN/AEffects of Overdose of Amoxycillin + SerratiopeptidaseN/AAmoxycillin
About AmoxycillinSemisynthetic Broad spectrum beta-lactam antibiotic, An aminopenicillin Derivative.Mechanism of Action of AmoxycillinAmoxycillin is a bactericidal drug. It is a Beta lactum antibiotic. It binds to the Penicillin binding protein in the cell wall of bacteria and inhibits the enzyme transpeptidase which is responsible for the transpeptidation reaction in peptidoglycan synthesis. It also activates the endogenous enzyme which degrades the peptidoglycan.These results in inhibition of protein synthesis and there by cell wall synthesis. Amoxycillin is active against gram positive and gram negative bacteria except penicillinase producing once.Pharmacokinets of AmoxycillinAbsorption .It is well absorbed after oral administration. Distribution: It is very widely distributed in the body .Metabolism: In significant metabolism. Excretion: It is excreted mainly through urine and small amount excreted
in breast milk
Onset of Action for Amoxycillin60 -120 minutesDuration of Action for Amoxycillin6-8 hoursHalf Life of Amoxycillin60 minutesSide Effects of Amoxycillin1.Aaphylaxis
2. Vomiting
3.Diarrhoea
4 Nausea
5.Rash
6.Urticaria
7.Thrombocytopenia
8.Nephritis
9.Seizure
10.Super infections.
Contra-indications of AmoxycillinHypersensitivity to Amoxicillin and other Penicillins.Special Precautions while taking Amoxycillin1.Mononucleosis
2.Lymphatic leukaemia
3.HIV infections
4.Hepatic impairment
5.Renal impairment
Pregnancy Related InformationUse with cautionOld Age Related InformationUse with cautionBreast Feeding Related InformationUse with cautionChildren Related InformationUse with cautionIndications for Amoxycillin1Urinary tract infections
2.Gonorrhoea
3 Meningitis
4.SABE
5.Respiratory tract infections
6.Septicemia
7.Soft tissue infections
8.Otitis media
9.Sinusitis
10.Tetanus
11.Biliarytract infections
12.Bronchitis
13.Salmonellosis
14.Typhoid
15.Gastroenteritis
16.Chlamydia infection
17.Paratyphoid fever
18.Dental infections
Interactions for AmoxycillinOral contraceptives: Efficacy reduced, may cause breakthrough bleeding or pregnancy.
Erythromycin, Tetracycline: Reduce efficacy.Typical Dosage for AmoxycillinADULT: 250 - 500 mg three to four times daily.
In severe infections dose can be increased to 3 - 6 g daily depending on the severity of infection.
CHILDREN:125 - 250 mg three to four times a day depending on the severity of infection.
Schedule of AmoxycillinHStorage Requirements for AmoxycillinIt should store at temperature below 25 degree C. Keep away from moisture and heat. Keep out of the reach of children.Effects of Missed Dosage of AmoxycillinTake the dose as soon as noticed and if it is the time to the next dose then skip the missed doseEffects of Overdose of AmoxycillinGive supportive measures and symptomatic treatment. If the patient is conscious induce emesis or gastric lavage followed by charcoal administration. Haemodialysis can be done if needed.
Serratiopeptidase
About SerratiopeptidaseA proteolytic enzyme, A powerful anti-inflammatory, anti-edemic.Mechanism of Action of SerratiopeptidaseThis anti-inflammatory proteolytic enzyme bind to the alpha-2-macroglobulin in the blood, which helps to mask its antigenicity.Then it is slowly transferred to the site of inflammation. Serratiopeptidase hydrolyze bradykinin, histamine, serotoxin responsible for oedema.It reduces swelling improves microcirculation and expectoration of sputum. Due to this action Serratiopeptidase has anti-inflammatory, antioedemic and fibrinolytic activity and act rapidly on localized inflammation.Pharmacokinets of SerratiopeptidaseOrally absorbed. In the case of enteric coated tablet absorption take place in the intestine. After absorption it is directly enter in to the bloodstream. It is excreted via urine and bile.Onset of Action for SerratiopeptidaseN/ADuration of Action for Serratiopeptidase8 to 10 hrsHalf Life of SerratiopeptidaseN/ASide Effects of Serratiopeptidase1. Hypersensitivity
2. Anorexia
3. Gastric discomfort
4. Nausea
5. Vomiting
6. Epistaxis
7. Diarrhoea
8. Skin rash
Contra-indications of Serratiopeptidase1. Hypersensitivity to this drug
2. Blood coagulation disorder
Special Precautions while taking Serratiopeptidase1. In patients with renal failure or hepatic failurePregnancy Related InformationContraindicatedOld Age Related InformationN/ABreast Feeding Related InformationContraindicatedChildren Related InformationN/AIndications for Serratiopeptidase1. Antiinflammatory
2. Antiswelling
3. Anti- rheumatoid
4. To promote transfer of antibiotics to the site of action
5. To promote lysis and discharge of sputum and pus
6. Bronchitis
7. Fibrocystic breast swelling
8. Sinusitis
9. Cough
10. Laryngitis
11. Fibromyalgia
12. Emphysema
13. Gout
Interactions for SerratiopeptidaseN/ATypical Dosage for SerratiopeptidaseOral-
Adults-5 to 10mg tab every 3 times daily.
10- 30 mg tab /day.
Schedule of SerratiopeptidaseN/AStorage Requirements for SerratiopeptidaseStore below 25 degree Celsius, protect from light and moisture.Effects of Missed Dosage of SerratiopeptidaseTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of SerratiopeptidaseGive supportive measures and symptomatic treatment.Home Delivery for Amoxycillin + Serratiopeptidase in Your City
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Amoxycillin + Serratiopeptidase is a generic medicine name and there are several brands available for it. Some of the brands for amoxycillin + serratiopeptidase might be better known than amoxycillin + serratiopeptidase itself. If the pharmacy that's willing to deliver medicines to your home doesn't have amoxycillin + serratiopeptidase in stock, you can ask for one of the branded alternatives for amoxycillin + serratiopeptidase.
