Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate Pharmacology

Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate

About Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Mechanism of Action of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Pharmacokinets of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Onset of Action for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Duration of Action for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Half Life of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Side Effects of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Contra-indications of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Special Precautions while taking Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
N/A
Pregnancy Related Information
Use with caution
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
1.Nutritional supplement
2.Antioxidant
Interactions for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Typical Dosage for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Schedule of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Storage Requirements for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Effects of Missed Dosage of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Effects of Overdose of Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate
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Lycopene

About Lycopene
Carotenoid;Terpenes and terpenoids, Dietary antioxidant.
Mechanism of Action of Lycopene
N/A
Pharmacokinets of Lycopene
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Onset of Action for Lycopene
N/A
Duration of Action for Lycopene
N/A
Half Life of Lycopene
N/A
Side Effects of Lycopene
N/A
Contra-indications of Lycopene
N/A
Special Precautions while taking Lycopene
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Lycopene
N/A
Interactions for Lycopene
N/A
Typical Dosage for Lycopene
N/A
Schedule of Lycopene
N/A
Storage Requirements for Lycopene
N/A
Effects of Missed Dosage of Lycopene
N/A
Effects of Overdose of Lycopene
N/A

Beta Carotene

About Beta Carotene
A natural precursor to Vitamin A.
Mechanism of Action of Beta Carotene
Beta-carotene acts as the precursor of Vitamin A and in the body it is converted in to Vitamin A. Vitamin A is required for a variety of physiological functions in the body such as: - 1).Proper functioning of retina and formation of pigment Rhodopsin during dark adaptation. 2).promotes differentiation and maintains structural integrity of epithelia over the body and also retard the malignancies of epithelial structures.3).Promotes mucous secretion. 4).Inhibits keratinization, 5). Maintains proper bone growth, 6).Maintenance of spermatogenesis, 7).Supports foetal development, 8).Improves resistance to infection. It is required for proper antibody response, normal lymphocyte proliferation and killer cell function.
Pharmacokinets of Beta Carotene
Absorption: Completely absorbed normally. Steatorrhoea, bile deficiency, and protein poor diet adversely affects the absorption and absorption requires bile salts, pancreatic lipase, and dietary fat.
Distribution: Stored primarily as palmitate in kupffer`s cells in liver. Circulates in the form of specific alpha-1 protein; retinol binding protein and transported to cellular retinol binding protein of target cells.
Metabolism: Metabolized in the liver.
Excretion: Excreted mainly through bile and a small amount is excreted through urine.
Onset of Action for Beta Carotene
N/A
Duration of Action for Beta Carotene
N/A
Half Life of Beta Carotene
N/A
Side Effects of Beta Carotene
Adverse effects occurs only with higher doses and toxicity
1. Nausea
2. Vomiting
3. Itching
4. Dermatitis
5. Exfoliation
6. Alopecia
7. Bone and joint pain
8. Anorexia
9. Irritability
10. Increased intracranial pressure
11. Hepatic impairment
12. Anaphylactic shock
Contra-indications of Beta Carotene
1. Hypervitaminosis A
2. Hypersensitivity to Beta Carotene
Special Precautions while taking Beta Carotene
1. Oral form should not use in patients with malabsorption syndrome.
2. In inadequate bile secretion oral route may be used with concurrent administration of bile salts.
3. I. V. route is contraindicated except for special water miscible forms intended for infusion with large parenteral volumes and should not use I. V. push of vitamin A of any type.
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
Indications for Beta Carotene
1. Vitamin A deficiency
2. Xerophthalmia
3. Acne
4. Ichthyosis
5. Bitot`s spots
6. Night blindness
Interactions for Beta Carotene
Cholestyramine: Absorption of Vitamin A is reduced due to reduced availability of fat stabilizing bile salts.
Mineral oil: Interferes with intestinal absorption of Vitamin A.
Oral Contraceptives: Plasma Vitamin A levels are significantly increased.
Typical Dosage for Beta Carotene
Severe vitamin A deficiency with xerophthalmia: 500000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Severe vitamin A deficiency: 100000 IU daily for 3 days followed by 50000 IU daily for 14 days. Then maintenance dosage of 10000 to 20000 IU for 2months followed by adequate dietary nutrition and RDA vitamin A supplements.
Children: 5000 to 10000 IU daily for 14 days.
Schedule of Beta Carotene
C1 (Oral)
C (Parenteral)
Storage Requirements for Beta Carotene
Store in a well closed, airtight container in a cool dry place.
Effects of Missed Dosage of Beta Carotene
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Beta Carotene
Discontinue the vitamin A if hypercalcaemia persists and administer I.V. saline, prednisolone, and calcitonin if required. Monitor hepatic function tests to detect liver damage.

Mecobalamin

About Mecobalamin
Water soluble, Form of Vitamin B12
Mechanism of Action of Mecobalamin
Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Pharmacokinets of Mecobalamin
Absorption: Absorbed after oral, sublingual, injection
Excretion: Excretion via urine
Onset of Action for Mecobalamin
N/A
Duration of Action for Mecobalamin
N/A
Half Life of Mecobalamin
N/A
Side Effects of Mecobalamin
1.Oral: Anorexia, nausea, vomiting and diarrhea
2.Parenteral: Rash, headache, hot sensation, diaphoresis and pain/induration at IM inj site
Contra-indications of Mecobalamin
N/A
Special Precautions while taking Mecobalamin
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
N/A
Indications for Mecobalamin
1.Peripheral neuropathies
2.Megaloblastic anaemia
Interactions for Mecobalamin
1.Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicines
2.Reduced serum concentrations with oral contraceptives
3.Reduced effects in anaemia with parenteral chloramphenicol
Typical Dosage for Mecobalamin
Peripheral neuropathies
Oral: Adult: 1500 mcg/day in 3 divided doses
Parenteral: 500 mcg daily IM/IV 3 times/wk

Megaloblastic anaemia caused by vitamin B12 deficiency
Parenteral: Adult: 500 mcg daily IM/IV 3 times/wk. Maintenance dose: After about 2 mth of therapy, reduce dose to single admin of 500 mcg every 1-3 mth.
Schedule of Mecobalamin
N/A
Storage Requirements for Mecobalamin
Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.


Effects of Missed Dosage of Mecobalamin
N/A
Effects of Overdose of Mecobalamin
N/A

Vit B6

About Vit B6
Physiological functions: It is involved as a coenzyme (Pyridoxal phosphate) in metabolism of tryptophan, in several metabolic transformations of amino acids including transamination, decarboxylation & racemization.
Deficiency symptoms: Peripheral neuritis, seizures, stomatitis, glossitis, anaemia, seborrhea like lesions.
Mechanism of Action of Vit B6
Vitamin B6 is a collective term for Pyridoxine, Pyridoxal, Pyridoxamine and their phosphorylated derivatives such as Pyridoxine phosphate, Pyridoxal phosphate and Pyridoxamine derivatives respectively. Vitamin B6 is essential for the metabolism of amino acid, glycogen and fatty acids, for nerve functions, for the formation of red blood cells and also helps the skin healthy. Vitamin B6 is also used for the synthesis of nucleic acid, Haemoglobin, Sphingomyelin, other Sphingolipids, Serotonin, Dopamine, Noradrenaline and GABA.
Pharmacokinets of Vit B6
Absorption: Vitamin B6 is readily absorbed after oral administration.
Distribution: It is mainly distributed in the body in protein bound form. It is stored primarily in the liver and to a lesser extent muscle and brain.
Metabolism: It is metabolised in the liver
Onset of Action for Vit B6
N/A
Duration of Action for Vit B6
N/A
Half Life of Vit B6
15-20 days
Side Effects of Vit B6
1. Neuropathy
2. Unstable gait
3. Drowsiness
4. Perioral numbness
5. Paresthesia
6. Numbness of feet
7. Somnolence
8. Sensory neuropathy
9. Ataxia
Contra-indications of Vit B6
1. Hypersensitivity to Vitamin B6
Special Precautions while taking Vit B6
N/A
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
Use with caution
Children Related Information
Use with caution
NEONATES: Contraindicated
Indications for Vit B6
1. Vitamin B6 deficiency including inadequate diet and drug induced causes
2. Neuropathy
3. Premenstrual syndrome
4. Hyperoxaluria type 1
5. Metabolic disorder
6. Isoniazid poisoning
Interactions for Vit B6
Cycloserine, Hydralazine, Isoniazide, Oral contraceptive, Penicillamine: Increase Pyridoxine requirement.
Levodopa: Pyridoxine reverses the therapeutic effect of Levodopa.
Phenobarbital, Phenytoin: Pyridoxine decreases serum level of these anticonvulsants.
Typical Dosage for Vit B6
Adult: 10 - 20 mg / day
Dietary deficiency: 2.5 -10 mg / day for effective therapeutic response is obtained.
Maintenance dose: 2 - 5 mg / day for several weeks.
Drug induced deficiency: 100 - 200 mg / day for 3 weeks.
Maintenance dose: 25 - 100 mg / day
Neuropathy: 50 - 200 mg /day
Premenstrual syndrome: 40 - 500 mg / day
Hyperoxaluria type 1: 25 - 300 mg / day
Metabolic disorder: 100-500 mg /day.
Isoniazid poisoning: Initial dose: 1 - 4 g as IV administration, then 1 g IM every 30 minute until Pyridoxine dose is equal to the Isoniazid dose has been given.
Schedule of Vit B6
N/A
Storage Requirements for Vit B6
Store it at 15 - 30 degree C. Protect from moisture and heat.
Effects of Missed Dosage of Vit B6
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Vit B6
Give supportive measures and symptomatic treatment. The signs of Pyridoxine overdose can be resolved by discontinuation (withdrawal) of Pyridoxine.

Folic Acid

About Folic Acid
Dietary supplement, Folate derivative( B9 ), Water Soluble Vitamin.
Mechanism of Action of Folic Acid
Folic acid reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively. Tetrahydrofolic acid acts as a coenzyme which mediates a number of one carbon transfer reactions by carrying a methyl group as an adduct. It involves a number of reactions such as 1).conversion of homocysteine to methionine. 2).synthesis of thymidylate which is an essential constituent of DNA from methylene-tetrahydrofolic acid. 3). Conversion of serine to glycine by tetrahydrofolic acid and forms methylene-tetrahydrofolic acid. 4).to introduce carbon units at position 2 and 8 during de novo purine synthesis requires formyl-tetrahydrofolic acid and methenyl-tetrahydrofolic acid.5).generation and utilization of "formate pool". 6).For mediating formino group transfer in histidine metabolism. Folic acid is required to maintain normal erythropoiesis and nucleoprotein synthesis.
Pharmacokinets of Folic Acid
Absorption: Well absorbed orally
Distribution: Widely distributed in the body and highest concentration is seen in liver. It appears in the CSF and breast milk
Metabolism: Metabolized in to N-methyl tetrahydrofolic acid in liver
Excretion: Extra drug is excreted unchanged in urine. A small portion of folate is lost by a combination of urinary and fecal excretion and oxidative cleavage of molecule.
Onset of Action for Folic Acid
Oral: 20 to 30minutes
I.V.: 5 minutes
I.M.:10 to 20minutes
Duration of Action for Folic Acid
Oral: 3 to 6 hours
I.V.:3 to 6minutes
I.M.:3 to 6hours
Half Life of Folic Acid
N/A
Side Effects of Folic Acid
N/A
Contra-indications of Folic Acid
N/A
Special Precautions while taking Folic Acid
1. In patients with undiagnosed anaemia; because it may mask pernicious anaemia
2. In pernicious anaemia and other megaloblastic where vitamin B12 is deficient
Pregnancy Related Information
May be used
Old Age Related Information
May be used
Breast Feeding Related Information
May be used
Children Related Information
May be used
Indications for Folic Acid
1. Megaloblastic anaemia
2. Folic acid deficiency
3. Anaemias of pregnancy
4. Nutritional anaemia
5. Alcoholism
6. Tropical sprue
7. Non tropical sprue
Interactions for Folic Acid
1. Hypersensitivity reactions with injection form
2. Bronchospasm
Typical Dosage for Folic Acid
Oral: 5mg 1 to 4 times daily; depending up on the severity of deficiency.
Maintenance dosage: Half of the therapeutic dosage.
Children: 2.5 to 5mg 1 to 2 times daily.
Schedule of Folic Acid
C1 (Oral)
C (Parenteral)
Storage Requirements for Folic Acid
Store at controlled room temperature at a range of 15 to 25 degree C in a well closed container. Protect from excess heat, light and moisture.
Effects of Missed Dosage of Folic Acid
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Folic Acid
Relatively non toxic. Provide symptomatic treatment and supportive measures.

Chromium

About Chromium
Chromium is by far the most pivotal nutrient involved in sugar metabolism. Trivalent chromium is a part of glucose tolerance factor, an essential activator of insulin mediated reactions. Chromium improves insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increases in insulin sensitivity. Thus it helps to maintain normal glucose metabolism and peripheral nerve function. A number of clinical studies have been conducted which show that chromium is an effective therapy for both Type I and Type II diabetes. Except for supplementation, there is no good way to rebuild the body?s stockpile of chromium.
Deficiency symptoms: Impaired glucose tolerance, peripheral neuropathy, ataxia, confusion.
Over dosage symptoms: In normal therapeutic doses side effects have not been reported except occasional insomnia. In the event of over dosage - nausea, vomiting, GI ulcers, renal/hepatic damage, convulsion, coma may occur.

Mechanism of Action of Chromium
Chromium picolinate acts by influencing carbohydrate metabolism. It stimulates Insulin mediated reactions and improves glucose tolerance. Chromium picolinate helps to improve; insulin binding, insulin receptor number, insulin internalization, beta cell sensitivity and insulin receptor enzymes with overall increase in insulin sensitivity. Thus it maintains normal glucose metabolism and peripheral nerve functions. It improves carbohydrate metabolism, increases energy and helps to control diabetes. It also helps to control weight.
Pharmacokinets of Chromium
Absorption: Well absorbed orally, Distribution: Widely distributed in the body in especially in to liver, kidney, bone, and spleen; normal plasma level is 1 to 5mcg/l. Excretion: Excreted mainly through urine.
Onset of Action for Chromium
N/A
Duration of Action for Chromium
N/A
Half Life of Chromium
N/A
Side Effects of Chromium
N/A
Contra-indications of Chromium
1. Hypersensitivity to the drug.
Special Precautions while taking Chromium
1. Prolonged therapy with the drug
2.Hypoglycaemia
3.In patients with Type II diabetes mellitus use of chromium picolinate is only under the direct medical supervision
4.Renal impairment
5.Hepatic impairment
Pregnancy Related Information
Use with caution
Old Age Related Information
Use with caution
Breast Feeding Related Information
Use with caution
Children Related Information
N/A
Indications for Chromium
1.Type I diabetes mellitus
2.Type II diabetes mellitus
3.Obesity.
Interactions for Chromium
N/A
Typical Dosage for Chromium
Oral: 200 mcg daily; increases up to 1mg daily if required.
Schedule of Chromium
N/A
Storage Requirements for Chromium
Store in a well closed container at a cool dry place.
Effects of Missed Dosage of Chromium
Take the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.
Effects of Overdose of Chromium
Give supportive measures and symptomatic treatment.

Selenium

About Selenium
A vital antioxidant, selenium acts with vitamin E to protect the immune system and maintain healthy heart function. It is needed for pancreatic function and tissue elasticity and has been shown to protect against radiation and toxic minerals. High levels of heart disease are associated with selenium-deficient soil in Finland and a tendency to fibrotic heart lesions is associated with selenium deficiency in parts of China. Best sources are butter, Brazil nuts, seafood and grains grown in selenium-rich soil.
Mechanism of Action of Selenium
N/A
Pharmacokinets of Selenium
N/A
Onset of Action for Selenium
N/A
Duration of Action for Selenium
N/A
Half Life of Selenium
N/A
Side Effects of Selenium
N/A
Contra-indications of Selenium
N/A
Special Precautions while taking Selenium
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Selenium
N/A
Interactions for Selenium
N/A
Typical Dosage for Selenium
N/A
Schedule of Selenium
N/A
Storage Requirements for Selenium
N/A
Effects of Missed Dosage of Selenium
N/A
Effects of Overdose of Selenium
N/A

Zinc Sulphate

About Zinc Sulphate
Zinc compound, An astringent , Adjunctive treatment of Wilson?s disease.
Mechanism of Action of Zinc Sulphate
N/A
Pharmacokinets of Zinc Sulphate
N/A
Onset of Action for Zinc Sulphate
N/A
Duration of Action for Zinc Sulphate
N/A
Half Life of Zinc Sulphate
N/A
Side Effects of Zinc Sulphate
N/A
Contra-indications of Zinc Sulphate
N/A
Special Precautions while taking Zinc Sulphate
N/A
Pregnancy Related Information
N/A
Old Age Related Information
N/A
Breast Feeding Related Information
N/A
Children Related Information
N/A
Indications for Zinc Sulphate
N/A
Interactions for Zinc Sulphate
N/A
Typical Dosage for Zinc Sulphate
N/A
Schedule of Zinc Sulphate
N/A
Storage Requirements for Zinc Sulphate
N/A
Effects of Missed Dosage of Zinc Sulphate
N/A
Effects of Overdose of Zinc Sulphate
N/A

Home Delivery for Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate in Your City

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However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate and other medicines and health products. Home delivery services for lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.

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Lycopene + Beta Carotene + Mecobalamin + Vit B6 + Folic Acid + Chromium +Selenium + Zinc Sulphate is a generic medicine name and there are several brands available for it. Some of the brands for lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate might be better known than lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate itself. If the pharmacy that's willing to deliver medicines to your home doesn't have lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate in stock, you can ask for one of the branded alternatives for lycopene + beta carotene + mecobalamin + vit b6 + folic acid + chromium +selenium + zinc sulphate.