Oxaprozin Pharmacology
Oxaprozin
Distribution: Protein-binding: >99%.
Metabolism: Hepatic via oxidation and glucuronidation.
Excretion: Via urine (5% unchanged, 65% as metabolites); via faeces (35% as metabolites).
2.Sedation
3.Somnolence
4.Confusion
5.Disturbance of sleep
6.Weakness
7.Malaise
8.Rash
9.Prutitus
10.Urticaria
11.Photosensitivity
12.Abdominal pain/distress
13.Anorexia
14.Flatulence
15.Vomiting
16.Constipation
17.Diarrhea
18.Dyspepsia
19.Nausea
20.Peptic ulcer and/or GI bleeding
21.Abnormalities in lfts
22.Stomatitis
23.Haemorrhoidal or rectal bleeding
24.Tinnitus
25.Dysuria
26.Oedema
27.BP changes
28.Haematuria
29.Renal insufficiency
30.Decreased menstrual flow
31.Anaemia
32.Thrombocytopenia
33.Leucopenia
34.Ecchymoses
35.Weight gain/loss
36.Blurred vision
37.Conjunctivitis
38.Dangerous:Anaphylactoid reactions, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe hepatic reactions
2.Known hypersensitivity to nsaids
3.Perioperative pain in CABG setting.
2.History of serious GI events, alcoholism, smoking, other factors known to be associated with peptic ulcer.
3.Uncompensated cardiac failure, history of hypertension, cardiac decompensation, chronic diuretic therapy, conditions predisposing to fluid retention.
4.Renal and hepatic impairment
5.Underlying coagulation defects or patients who are undergoing surgical procedures where a high degree of homeostasis is required.
2.For relief of the signs and symptoms of rheumatoid arthritis.
3.For relief of the signs and symptoms of juvenile rheumatoid arthritis.
2.May increase effects of oral anticoagulants
3.May reduce effects of ?-blockers, diuretics and other antihypertensive agents
4.May increase risk of methotrexate and lithium toxicity
Renal impairment: Severe or on dialysis: 600 mg once daily. Increase to 1.2 g daily if needed Oral.
Juvenile rheumatoid arthritis
Child: ?6 yr: Wt 22-31 kg: 600 mg; 32-54 kg: 900 mg; ?55 kg: 1200 mg. All doses to be given once daily.
In patients with severe renal impairment, or in those undergoing hemodialysis, low body wt or mild disease: Dosage should be initiated at 600 mg daily; dosage may be increased to 1.2 g daily with caution.
Management: Supportive and symptomatic. Multiple admin of charcoal may be required to reduce potential for delayed toxicities.
Home Delivery for Oxaprozin in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including oxaprozin.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for oxaprozin and other medicines and health products. Home delivery services for oxaprozin may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take oxaprozin only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for oxaprozin before they complete the sale. You can get this information while placing the order for oxaprozin with the pharmacy.
Oxaprozin is a generic medicine name and there are several brands available for it. Some of the brands for oxaprozin might be better known than oxaprozin itself. If the pharmacy that's willing to deliver medicines to your home doesn't have oxaprozin in stock, you can ask for one of the branded alternatives for oxaprozin.
