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- Pharmacology For Etodolac + Thiocolchicoside
Etodolac + Thiocolchicoside Pharmacology
Etodolac + Thiocolchicoside
About Etodolac + ThiocolchicosideN/AMechanism of Action of Etodolac + ThiocolchicosideN/APharmacokinets of Etodolac + ThiocolchicosideN/AOnset of Action for Etodolac + ThiocolchicosideN/ADuration of Action for Etodolac + ThiocolchicosideN/AHalf Life of Etodolac + ThiocolchicosideN/ASide Effects of Etodolac + ThiocolchicosideN/AContra-indications of Etodolac + ThiocolchicosideN/ASpecial Precautions while taking Etodolac + ThiocolchicosideN/APregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Etodolac + Thiocolchicoside1.Treatment of inflammation and pain caused by osteoarthritis and rheumatoid arthritis.
2.For the treatment of patients with acute painful musculoskeletal conditions.
Interactions for Etodolac + ThiocolchicosideN/ATypical Dosage for Etodolac + ThiocolchicosideN/ASchedule of Etodolac + ThiocolchicosideN/AStorage Requirements for Etodolac + ThiocolchicosideN/AEffects of Missed Dosage of Etodolac + ThiocolchicosideN/AEffects of Overdose of Etodolac + ThiocolchicosideN/AEtodolac
About EtodolacA member of pyranocarboxylic acid group of NSAID, Analgesic, Anti-inflammatory.Mechanism of Action of EtodolacEtodolac is an acetic acid derivative. Etodolac produces its analgesics and anti-inflammatory actions by inhibiting Prostaglandin synthesis. It has also some COX2 selective action. So its anti-inflammatory action and the frequency of gastric irritation is less as compared to other NSAIDs.Pharmacokinets of EtodolacAbsorption: It is rapidly and well absorbed after oral administration. Distribution: It s distributed mainly in protein bound form. Metabolism: It undergoes metabolism in the liver. Excretion: It is excreted mainly in urine.Onset of Action for EtodolacN/ADuration of Action for EtodolacN/AHalf Life of Etodolac7 -10 hoursSide Effects of Etodolac1.Abdominal pain
2.Constipation
3.Diarrhoea
4.Dyspepsia
5.Flatulence
6.Heartburn
7.Nausea
8.Gastrointestinal ulcers
9.Vomiting.
10.Anemia
11.Dizziness
12.Oedema
13.Elevated liver enzymes
14.Headaches
15.Increased bleeding time
16.Pruritis
17.Rashes
18. Tinnitus
Contra-indications of EtodolacHypersensitivity to EtodolacSpecial Precautions while taking Etodolac1.Hepatic impairment
2.Anaemia
3.Asthma
Pregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationContraindicatedIndications for Etodolac1. Osteoarthritis
2. Rheumatoid arthritis
3..Pain
Interactions for EtodolacN/ATypical Dosage for EtodolacAdult: 600mg - 1000mg / day in 2 - 3 divided doses.
Pain: 200 - 400 mg 3 - 4 times daily. Maximum 1g
Schedule of EtodolacHStorage Requirements for EtodolacStore at room temperature.Protect from heat, light and moisture. Keep out of the reach of children.Effects of Missed Dosage of EtodolacTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of EtodolacGive supportive measures and symptomatic treatment.Thiocolchicoside
About ThiocolchicosideA GABA-A antagonist,semi-synthetic colchicoside(natural compound) derivative, A centrally acting muscle relaxant.Mechanism of Action of ThiocolchicosideThiocolchicide is a GABA-A receptor antagonist, which binds to GABA-A and strychnine sensitive glycine receptors. This results the reduction of spasticity. It also has myorelaxant effects at the supraspinal level, via complex regulatory mechanisms.Pharmacokinets of ThiocolchicosideN/AOnset of Action for ThiocolchicosideN/ADuration of Action for ThiocolchicosideN/AHalf Life of ThiocolchicosideN/ASide Effects of Thiocolchicoside1. Diarrhoea
2. Gastralgia
3. Nausea
4. Vomiting
5. Drowsiness
6. Anaphylactic reaction
Contra-indications of Thiocolchicoside1. Contraindicated in patients with hypersensitivity to the drugSpecial Precautions while taking Thiocolchicoside1. Use with caution in patients with diarrheaPregnancy Related InformationContraindicatedOld Age Related InformationUse with cautionBreast Feeding Related InformationContraindicatedChildren Related InformationUse with cautionIndications for ThiocolchicosidePainful muscle spasm associated with
1. Degenerative vertebral disorders
2. Torticollis
3. Dorsal pain
4. Low back pain
5. Traumatological disorders
6. Neurological disorders
Interactions for ThiocolchicosideNo known interactions with other drugs.Typical Dosage for ThiocolchicosideAdult-
Oral- 4mg twice a day for 5 to 7 days.
Intramuscular-
4mg twice a day for 3 to 5 days.
Schedule of ThiocolchicosideN/AStorage Requirements for ThiocolchicosideN/AEffects of Missed Dosage of ThiocolchicosideTake the missed dose as soon as noticed and if it is the time for next dose then skip the missed dose. Continue the regular schedule. Do not double the dose.Effects of Overdose of ThiocolchicosideGive symptomatic and supportive treatment.Home Delivery for Etodolac + Thiocolchicoside in Your City
Medicine India is just a publishing medium for medicine related information and does not provide services or sales of medicines including etodolac + thiocolchicoside.
However, we do publish a comprehensive directory of Pharmacies, Chemists and Druggists in cities all over India. You can use this directory to find the medicine stores in your city (or area) that provide home delivery services for etodolac + thiocolchicoside and other medicines and health products. Home delivery services for etodolac + thiocolchicoside may be free or they may cost you depending on the pharmacy and the minimum order requirements. It would be best to get this clarified while placing the order.
Please be aware that you should take etodolac + thiocolchicoside only if a doctor has recommended or prescribed it. Some or all pharmacies who provide a home delivery service for medicines might insist on a prescription for etodolac + thiocolchicoside before they complete the sale. You can get this information while placing the order for etodolac + thiocolchicoside with the pharmacy.
Etodolac + Thiocolchicoside is a generic medicine name and there are several brands available for it. Some of the brands for etodolac + thiocolchicoside might be better known than etodolac + thiocolchicoside itself. If the pharmacy that's willing to deliver medicines to your home doesn't have etodolac + thiocolchicoside in stock, you can ask for one of the branded alternatives for etodolac + thiocolchicoside.
